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2OYQ
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BU of 2oyq by Molmil
Crystal structure of RB69 gp43 in complex with DNA with 5-NIMP opposite an abasic site analog
Descriptor: 1-{2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-ERYTHRO-PENTOFURANOSYL}-5-NITRO -1H-INDOLE, DNA polymerase, MAGNESIUM ION, ...
Authors:Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S.
Deposit date:2007-02-22
Release date:2007-10-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Caught bending the a-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide.
Biochemistry, 46, 2007
4LZB
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BU of 4lzb by Molmil
Uracil binding pocket in Vaccinia virus uracil DNA glycosylase
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
Authors:Schormann, N, Chattopadhyay, D.
Deposit date:2013-07-31
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structure of the uracil complex of Vaccinia virus uracil DNA glycosylase.
Acta Crystallogr.,Sect.F, 69, 2013
1UA0
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BU of 1ua0 by Molmil
Aminofluorene DNA adduct at the pre-insertion site of a DNA polymerase
Descriptor: 2-AMINOFLUORENE, DNA polymerase I, DNA primer strand, ...
Authors:Hsu, G.W, Kiefer, J.R, Becherel, O.J, Fuchs, R.P.P, Beese, L.S.
Deposit date:2004-08-11
Release date:2004-09-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase
J.Biol.Chem., 279, 2004
3ABE
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BU of 3abe by Molmil
Structure of human REV7 in complex with a human REV3 fragment in a tetragonal crystal
Descriptor: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B
Authors:Hara, K, Hashimoto, H, Murakumo, Y, Kobayashi, S, Kogame, T, Unzai, S, Akashi, S, Takeda, S, Shimizu, T, Sato, M.
Deposit date:2009-12-07
Release date:2010-02-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase {zeta} and REV1
J.Biol.Chem., 285, 2010
2DTU
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BU of 2dtu by Molmil
Crystal structure of the beta hairpin loop deletion variant of RB69 gp43 in complex with DNA containing an abasic site analog
Descriptor: 5'-D(*CP*GP*(3DR)P*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*GP*A)-3', DNA polymerase
Authors:Aller, P, Hogg, M, Konigsberg, W, Wallace, S.S, Doublie, S.
Deposit date:2006-07-15
Release date:2006-12-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family.
J.Biol.Chem., 282, 2007
7NPF
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BU of 7npf by Molmil
Vibrio cholerae ParA2-ATPyS-DNA filament
Descriptor: AAA family ATPase, DNA (49-MER), MAGNESIUM ION, ...
Authors:Parker, A.V, Bergeron, J.R.C.
Deposit date:2021-02-26
Release date:2021-10-06
Last modified:2021-10-20
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:The structure of the bacterial DNA segregation ATPase filament reveals the conformational plasticity of ParA upon DNA binding.
Nat Commun, 12, 2021
5CBX
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BU of 5cbx by Molmil
AncGR DNA Binding Domain - (+)GRE Complex
Descriptor: AncGR DNA Binding Domain, DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*AP*GP*TP*GP*TP*TP*CP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*CP*TP*CP*TP*GP*TP*TP*CP*TP*G)-3'), ...
Authors:Hudson, W.H, Ortlund, E.A.
Deposit date:2015-07-01
Release date:2015-12-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space.
Proc.Natl.Acad.Sci.USA, 113, 2016
2OR1
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BU of 2or1 by Molmil
RECOGNITION OF A DNA OPERATOR BY THE REPRESSOR OF PHAGE 434. A VIEW AT HIGH RESOLUTION
Descriptor: 434 REPRESSOR, DNA (5'-D(*AP*AP*GP*TP*AP*CP*AP*AP*AP*CP*TP*TP*TP*CP*TP*TP*G P*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*CP*AP*AP*GP*AP*AP*AP*GP*TP*TP*TP*GP*T P*AP*CP*T)-3')
Authors:Aggarwal, A.K, Rodgers, D.W, Drottar, M, Ptashne, M, Harrison, S.C.
Deposit date:1989-09-05
Release date:1989-09-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Recognition of a DNA operator by the repressor of phage 434: a view at high resolution.
Science, 242, 1988
6Z1A
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BU of 6z1a by Molmil
Ternary complex of Staphylococcus aureus DNA gyrase with AMK12 and DNA
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
Authors:Kolaric, A, Germe, T, Hrast, M, Stevenson, C.E.M, Lawson, D.M, Burton, N, Voros, J, Maxwell, A, Minovski, N, Anderluh, M.
Deposit date:2020-05-13
Release date:2020-11-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Potent DNA gyrase inhibitors bind asymmetrically to their target using symmetrical bifurcated halogen bonds.
Nat Commun, 12, 2021
1D37
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BU of 1d37 by Molmil
INFLUENCE OF AGLYCONE MODIFICATIONS ON THE BINDING OF ANTHRACYCLINE DRUGS TO DNA: THE MOLECULAR STRUCTURE OF IDARUBICIN AND 4-O-DEMETHYL-11-DEOXYDOXORUBICIN COMPLEXED TO D(CGATCG)
Descriptor: 1-O-DEMETHYL-6-DEOXYDOXORUBICIN, DNA (5'-D(*CP*GP*AP*TP*CP*G)-3')
Authors:Gao, Y.-G, Wang, A.H.-J.
Deposit date:1991-04-23
Release date:1992-04-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Influence of aglycone modifications on the binding of anthracycline drugs to DNA: the molecular structure of idarubicin and 4-O-demethyl-11-deoxydoxorubicin complexed to d(CGATCG).
Anti-Cancer Drug Des., 6, 1991
7NX5
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BU of 7nx5 by Molmil
Crystal structure of the Epstein-Barr Virus protein ZEBRA (BZLF1, Zta) bound to a methylated DNA duplex
Descriptor: Trans-activator protein BZLF1, meZRE2 DNA (bottom strand), meZRE2 DNA (top strand)
Authors:Bernaudat, F, Petosa, C.
Deposit date:2021-03-17
Release date:2021-12-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of DNA methylation-dependent site selectivity of the Epstein-Barr virus lytic switch protein ZEBRA/Zta/BZLF1.
Nucleic Acids Res., 50, 2022
8QAM
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BU of 8qam by Molmil
vaccinia virus Uracil DNA glycosidase mutant I197K-V200E-L204K
Descriptor: GLYCEROL, SULFATE ION, Uracil-DNA glycosylase
Authors:Tarbouriech, N, Burmeister, W.P.
Deposit date:2023-08-23
Release date:2024-05-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Structure and flexibility of the DNA polymerase holoenzyme of vaccinia virus.
Plos Pathog., 20, 2024
2D5V
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BU of 2d5v by Molmil
Crystal structure of HNF-6alpha DNA-binding domain in complex with the TTR promoter
Descriptor: 5'-D(*AP*TP*TP*AP*TP*TP*GP*AP*CP*TP*TP*AP*GP*A)-3', 5'-D(*TP*CP*TP*AP*AP*GP*TP*CP*AP*AP*TP*AP*AP*T)-3', ACETATE ION, ...
Authors:Iyaguchi, D, Yao, M, Watanabe, N, Nishihira, J, Tanaka, I.
Deposit date:2005-11-07
Release date:2006-12-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:DNA recognition mechanism of the ONECUT homeodomain of transcription factor HNF-6
Structure, 15, 2007
5OS9
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BU of 5os9 by Molmil
Structure of the B3 DNA-Binding Domain of NGA1
Descriptor: B3 domain-containing transcription factor NGA1
Authors:Sasnauskas, G, Manakova, E.
Deposit date:2017-08-17
Release date:2018-09-05
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:DNA recognition by Arabidopsis transcription factors ABI3 and NGA1.
FEBS J., 285, 2018
362D
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BU of 362d by Molmil
THE STRUCTURE OF D(TGCGCA)2 AND A COMPARISON TO OTHER Z-DNA HEXAMERS
Descriptor: COBALT HEXAMMINE(III), DNA (5'-D(*TP*GP*CP*GP*CP*A)-3')
Authors:Harper, N.A, Brannigan, J.A, Buck, M, Lewis, R.J, Moore, M.H, Schneider, B.
Deposit date:1997-08-20
Release date:1997-11-20
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure of d(TGCGCA)2 and a comparison to other DNA hexamers.
Acta Crystallogr.,Sect.D, 54, 1998
2DES
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BU of 2des by Molmil
INTERACTIONS BETWEEN MORPHOLINYL ANTHRACYCLINES AND DNA: THE CRYSTAL STRUCTURE OF A MORPHOLINO DOXORUBICIN BOUND TO D(CGTACG)
Descriptor: 3'-DESAMINO-3'-(2-METHOXY-4-MORPHOLINYL)-DOXORUBICIN, DNA (5'-D(*CP*GP*TP*AP*CP*G)-3'), MAGNESIUM ION, ...
Authors:Cirilli, M, Bachechi, F, Ughetto, G, Colonna, F.P, Capobianco, M.L.
Deposit date:1993-03-16
Release date:1993-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Interactions between morpholinyl anthracyclines and DNA. The crystal structure of a morpholino doxorubicin bound to d(CGTACG).
J.Mol.Biol., 230, 1993
5BOX
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BU of 5box by Molmil
Structure of TrmBL2, an archaeal chromatin protein, shows a novel mode of DNA binding.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (25-MER), DNA TGM (25-MER), ...
Authors:Ahmad, M.U, Diederichs, K, Welte, W.
Deposit date:2015-05-27
Release date:2015-09-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Insights into Nonspecific Binding of DNA by TrmBL2, an Archaeal Chromatin Protein.
J.Mol.Biol., 427, 2015
6QX1
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BU of 6qx1 by Molmil
2.7A structure of benzoisoxazole 3 with S.aureus DNA gyrase and DNA.
Descriptor: (2~{R})-2-[[5-(2-chlorophenyl)-1,2-benzoxazol-3-yl]oxy]-2-phenyl-ethanamine, CHLORIDE ION, DNA (5'-D(*AP*GP*CP*CP*GP*TP*AP*GP*GP*TP*AP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3'), ...
Authors:Bax, B.D.
Deposit date:2019-03-06
Release date:2019-04-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure-guided design of antibacterials that allosterically inhibit DNA gyrase.
Bioorg.Med.Chem.Lett., 29, 2019
6L84
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BU of 6l84 by Molmil
Complex of DNA polymerase IV and D-DNA duplex
Descriptor: CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*C)-3'), DNA (5'-D(P*CP*GP*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ...
Authors:Chung, H.S, An, J, Hwang, D.
Deposit date:2019-11-04
Release date:2020-07-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.602 Å)
Cite:The crystal structure of a natural DNA polymerase complexed with mirror DNA.
Chem.Commun.(Camb.), 56, 2020
5B43
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BU of 5b43 by Molmil
Crystal structure of Acidaminococcus sp. Cpf1 in complex with crRNA and target DNA
Descriptor: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cpf1, DNA (34-MER), ...
Authors:Yamano, T, Nishimasu, H, Hirano, H, Nakane, T, Ishitani, R, Nureki, O.
Deposit date:2016-03-30
Release date:2016-05-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA
Cell, 165, 2016
5CA7
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BU of 5ca7 by Molmil
Human DNA polymerase lambda- MgdGTP binary and complex with 6 paired DNA
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-06-29
Release date:2016-02-24
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.522 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
4DQY
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BU of 4dqy by Molmil
Structure of Human PARP-1 bound to a DNA double strand break
Descriptor: 1,2-ETHANEDIOL, DNA (26-MER), Poly [ADP-ribose] polymerase 1, ...
Authors:Langelier, M.F, Pascal, J.M.
Deposit date:2012-02-16
Release date:2012-05-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structural basis for DNA damage-dependent poly(ADP-ribosyl)ation by human PARP-1.
Science, 336, 2012
3NGD
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BU of 3ngd by Molmil
Structural Basis for Proficient Incorporation of dTTP Opposite O6-methylguanine by Human DNA Polymerase Iota
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*TP*CP*TP*(6OG)P*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*(DOC))-3', DNA polymerase iota
Authors:Pence, M.G.
Deposit date:2010-06-11
Release date:2010-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Proficient Incorporation of dTTP Opposite O6-Methylguanine by Human DNA Polymerase {iota}.
J.Biol.Chem., 285, 2010
4WS6
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BU of 4ws6 by Molmil
Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with 5-aminouracil, Form I
Descriptor: 1,2-ETHANEDIOL, 5-AMINO-1H-PYRIMIDINE-2,4-DIONE, CHLORIDE ION, ...
Authors:Arif, S.M, Geethanandan, K, Mishra, P, Surolia, A, Varshney, U, Vijayan, M.
Deposit date:2014-10-25
Release date:2015-07-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications.
Acta Crystallogr.,Sect.D, 71, 2015
4WPL
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BU of 4wpl by Molmil
Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with uracil, Form I
Descriptor: ACETATE ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
Authors:Arif, S.M, Geethanandan, K, Mishra, P, Surolia, A, Varshney, U, Vijayan, M.
Deposit date:2014-10-20
Release date:2015-07-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications.
Acta Crystallogr.,Sect.D, 71, 2015

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