2DES
INTERACTIONS BETWEEN MORPHOLINYL ANTHRACYCLINES AND DNA: THE CRYSTAL STRUCTURE OF A MORPHOLINO DOXORUBICIN BOUND TO D(CGTACG)
Summary for 2DES
Entry DOI | 10.2210/pdb2des/pdb |
Descriptor | DNA (5'-D(*CP*GP*TP*AP*CP*G)-3'), 3'-DESAMINO-3'-(2-METHOXY-4-MORPHOLINYL)-DOXORUBICIN, SODIUM ION, ... (5 entities in total) |
Functional Keywords | right handed dna, double helix, complexed with drug, dna |
Total number of polymer chains | 2 |
Total formula weight | 4975.99 |
Authors | Cirilli, M.,Bachechi, F.,Ughetto, G.,Colonna, F.P.,Capobianco, M.L. (deposition date: 1993-03-16, release date: 1993-07-15, Last modification date: 2024-02-14) |
Primary citation | Cirilli, M.,Bachechi, F.,Ughetto, G.,Colonna, F.P.,Capobianco, M.L. Interactions between morpholinyl anthracyclines and DNA. The crystal structure of a morpholino doxorubicin bound to d(CGTACG). J.Mol.Biol., 230:878-889, 1993 Cited by PubMed: 8478940DOI: 10.1006/jmbi.1993.1208 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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