2U2A
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2SDF
| SOLUTION NMR STRUCTURE OF STROMAL CELL-DERIVED FACTOR-1 (SDF-1), 30 STRUCTURES | Descriptor: | STROMAL CELL-DERIVED FACTOR-1 | Authors: | Crump, M.P, Rajarathnam, K, Clark-Lewis, I, Sykes, B.D. | Deposit date: | 1998-03-07 | Release date: | 1998-06-17 | Last modified: | 2024-10-16 | Method: | SOLUTION NMR | Cite: | Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1. EMBO J., 16, 1997
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6A3C
| MVM NES mutant Nm12 in complex with CRM1-Ran-RanBP1 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... | Authors: | Sun, Q, Li, Y. | Deposit date: | 2018-06-15 | Release date: | 2019-06-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
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8A60
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8A4F
| Human Interleukin-4 mutant - C3T-IL4 | Descriptor: | Interleukin-4 | Authors: | Vaz, D.C, Rodrigues, J.R, Mueller, T.D, Sebald, W, Redfield, C, Brito, R.M.M. | Deposit date: | 2022-06-11 | Release date: | 2023-10-18 | Last modified: | 2024-10-16 | Method: | SOLUTION NMR | Cite: | Lessons on protein structure from interleukin-4: All disulfides are not created equal. Proteins, 92, 2024
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5XT2
| Crystal structures of full-length FixJ from B. japonicum crystallized in space group P212121 | Descriptor: | FORMIC ACID, GLYCEROL, MAGNESIUM ION, ... | Authors: | Nishizono, Y, Hisano, T, Shiro, Y, Sawai, H, Wright, G.S.A, Saeki, A, Hikima, T, Nakamura, H, Yamamoto, M, Antonyuk, S.V, Hasnain, S.S. | Deposit date: | 2017-06-16 | Release date: | 2018-05-23 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.652 Å) | Cite: | Architecture of the complete oxygen-sensing FixL-FixJ two-component signal transduction system. Sci Signal, 11, 2018
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6AE2
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6A9A
| Ternary complex crystal structure of dCH with dCMP and THF | Descriptor: | (6S)-5,6,7,8-TETRAHYDROFOLATE, 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, Deoxycytidylate 5-hydroxymethyltransferase, ... | Authors: | Park, S.H, Song, H.K. | Deposit date: | 2018-07-12 | Release date: | 2019-01-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A cytosine modification mechanism revealed by the structure of a ternary complex of deoxycytidylate hydroxymethylase from bacteriophage T4 with its cofactor and substrate. Iucrj, 6, 2019
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2UWJ
| Structure of the heterotrimeric complex which regulates type III secretion needle formation | Descriptor: | NICKEL (II) ION, TYPE III EXPORT PROTEIN PSCE, TYPE III EXPORT PROTEIN PSCF, ... | Authors: | Quinaud, M, Ple, S, Job, V, Contreras-Martel, C, Simorre, J.P, Attree, I, Dessen, A. | Deposit date: | 2007-03-22 | Release date: | 2007-05-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the heterotrimeric complex that regulates type III secretion needle formation. Proc. Natl. Acad. Sci. U.S.A., 104, 2007
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2UW2
| Crystal structure of human ribonucleotide reductase subunit R2 | Descriptor: | FE (III) ION, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE M2 SUBUNIT | Authors: | Welin, M, Ogg, D, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Kotenyova, T, Magnusdottir, A, Moche, M, Nilsson-Ehle, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Stenmark, P, Uppenberg, J, Thorsell, A.G, Van Den Berg, S, Wallden, K, Weigelt, J, Nordlund, P. | Deposit date: | 2007-03-16 | Release date: | 2007-04-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of Human Ribonucleotide Reductase Subunit R2 To be Published
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8A7I
| Crystal structure of BRD9 bromodomain in complex with compound EA-89 | Descriptor: | Bromodomain-containing protein 9, ~{N}-[1,1-bis(oxidanylidene)thian-4-yl]-7-[3-methyl-1-(piperidin-4-ylmethyl)indol-5-yl]-4-oxidanylidene-5-propyl-thieno[3,2-c]pyridine-2-carboxamide | Authors: | Faller, M, Zink, F. | Deposit date: | 2022-06-21 | Release date: | 2022-08-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | BRD9 degraders as chemosensitizers in acute leukemia and multiple myeloma. Blood Cancer J, 12, 2022
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6AE8
| Structure insight into histone chaperone Chz1-mediated H2A.Z recognition and replacement | Descriptor: | BICINE, Histone H2A.Z-specific chaperone CHZ1, Histone H2B.1,Histone H2A.Z | Authors: | Wang, Y.Y, Shan, S, Zhou, Z. | Deposit date: | 2018-08-03 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural insights into histone chaperone Chz1-mediated H2A.Z recognition and histone replacement. Plos Biol., 17, 2019
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7ZPK
| Mammalian Dicer in the "pre-dicing state" with pre-miR-15a substrate and TARBP2 subunit | Descriptor: | 59-nt precursor of miR-15a, Endoribonuclease Dicer, RISC-loading complex subunit TARBP2 | Authors: | Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J. | Deposit date: | 2022-04-27 | Release date: | 2022-11-16 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.81 Å) | Cite: | Structural and functional basis of mammalian microRNA biogenesis by Dicer. Mol.Cell, 82, 2022
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5ZQV
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6A38
| MVM NS2 NES in complex with CRM1-Ran-RanBP1 | Descriptor: | 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... | Authors: | Sun, Q, Li, Y. | Deposit date: | 2018-06-15 | Release date: | 2019-06-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
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2UZ8
| The crystal structure of p18, human translation elongation factor 1 epsilon 1 | Descriptor: | EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1, GLYCEROL | Authors: | Kang, B.S, Kim, K.J, Kim, M.H, Oh, Y.S, Kim, S. | Deposit date: | 2007-04-26 | Release date: | 2008-03-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Determination of Three-Dimensional Structure and Residues of the Novel Tumor Suppressor Aimp3/P18 Required for the Interaction with Atm. J.Biol.Chem., 283, 2008
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7ZPI
| Mammalian Dicer in the "dicing state" with pre-miR-15a substrate | Descriptor: | 59-nt precursor of miR-15a, Endoribonuclease Dicer | Authors: | Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J. | Deposit date: | 2022-04-27 | Release date: | 2022-11-16 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (5.91 Å) | Cite: | Structural and functional basis of mammalian microRNA biogenesis by Dicer. Mol.Cell, 82, 2022
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6A6X
| The crystal structure of the Mtb MazE-MazF-mt9 complex | Descriptor: | Antitoxin MazE7, Probable endoribonuclease MazF7, SULFATE ION | Authors: | Xie, W, Chen, R, Tu, J. | Deposit date: | 2018-06-29 | Release date: | 2019-07-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and Biochemical Characterization of the Cognate and Heterologous Interactions of the MazEF-mt9 TA System. Acs Infect Dis., 5, 2019
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1AIH
| CATALYTIC DOMAIN OF BACTERIOPHAGE HP1 INTEGRASE | Descriptor: | HP1 INTEGRASE, MAGNESIUM ION, SULFATE ION | Authors: | Hickman, A.B, Waninger, S, Scocca, J.J, Dyda, F. | Deposit date: | 1997-04-17 | Release date: | 1997-08-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular organization in site-specific recombination: the catalytic domain of bacteriophage HP1 integrase at 2.7 A resolution. Cell(Cambridge,Mass.), 89, 1997
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6AAX
| Crystal structure of TFB1M and h45 with SAM in homo sapiens | Descriptor: | DI(HYDROXYETHYL)ETHER, Dimethyladenosine transferase 1, mitochondrial, ... | Authors: | Liu, X, Shen, S, Wu, P, Li, F, Gong, Q, Wu, J, Zhang, H, Shi, Y. | Deposit date: | 2018-07-19 | Release date: | 2019-06-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.994 Å) | Cite: | Structural insights into dimethylation of 12S rRNA by TFB1M: indispensable role in translation of mitochondrial genes and mitochondrial function. Nucleic Acids Res., 47, 2019
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6A4E
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2V93
| EQUILLIBRIUM MIXTURE OF OPEN AND PARTIALLY-CLOSED SPECIES IN THE APO STATE OF MALTODEXTRIN-BINDING PROTEIN BY PARAMAGNETIC RELAXATION ENHANCEMENT NMR | Descriptor: | 1-(1-HYDROXY-2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL)PYRROLIDINE-2,5-DIONE, MALTOSE-BINDING PERIPLASMIC PROTEIN | Authors: | Clore, G.M, Tang, C. | Deposit date: | 2007-08-21 | Release date: | 2007-11-06 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Open-to-Closed Transition in Apo Maltose-Binding Protein Observed by Paramagnetic NMR. Nature, 449, 2007
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2V6X
| Stractural insight into the interaction between ESCRT-III and Vps4 | Descriptor: | DOA4-INDEPENDENT DEGRADATION PROTEIN 4, SULFATE ION, VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4 | Authors: | Obita, T, Perisic, O, Ghazi-Tabatabai, S, Saksena, S, Emr, S.D, Williams, R.L. | Deposit date: | 2007-07-23 | Release date: | 2007-10-16 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structural Basis for Selective Recognition of Escrt-III by the Aaa ATPase Vps4 Nature, 449, 2007
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6AF4
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1FM6
| THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN RXRALPHA AND PPARGAMMA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH 9-CIS RETINOIC ACID AND ROSIGLITAZONE AND CO-ACTIVATOR PEPTIDES. | Descriptor: | (9cis)-retinoic acid, 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), ... | Authors: | Gampe Jr, R.T, Montana, V.G, Lambert, M.H, Miller, A.B, Bledsoe, R.K, Milburn, M.V, Kliewer, S.A, Willson, T.M, Xu, H.E. | Deposit date: | 2000-08-16 | Release date: | 2001-02-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors. Mol.Cell, 5, 2000
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