PDB: 26577 resultsInfo pagesStatus searchChemie searchBIRD

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2RFA	Crystal structure of the mouse TRPV6 ankyrin repeat domain Descriptor: Transient receptor potential cation channel subfamily V member 6 Authors: Phelps, C.B, Huang, R.J, Wang, R.R, Gaudet, R. Deposit date: 2007-09-28 Release date: 2008-02-19 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural analyses of the ankyrin repeat domain of TRPV6 and related TRPV ion channels. Biochemistry, 47, 2008
6F7G	Tryptophan Repressor TrpR from E.coli with 5-Methyltryptamine Descriptor: 2-(5-methyl-1~{H}-indol-3-yl)ethanamine, Trp operon repressor Authors: Stiel, A.C, Shanmugaratnam, S, Hocker, B. Deposit date: 2017-12-08 Release date: 2018-12-19 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.656 Å) Cite: Tryptophan Repressor TrpR: A ligand specificity study To Be Published
6F9K	Tryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan as ligand Descriptor: 5-methyl-L-tryptophan, SULFATE ION, Trp operon repressor Authors: Stiel, A.C, Shanmugaratnam, S, Hocker, B. Deposit date: 2017-12-14 Release date: 2019-01-30 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.399 Å) Cite: Tryptophan Repressor TrpR from E.coli: A ligand binding study To Be Published
6AYF	TRPML3/ML-SA1 complex at pH 7.4 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-3 Authors: Zhou, X, Li, M, Su, D, Jia, Q, Li, H, Li, X, Yang, J. Deposit date: 2017-09-08 Release date: 2017-11-08 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.62 Å) Cite: Cryo-EM structures of the human endolysosomal TRPML3 channel in three distinct states. Nat. Struct. Mol. Biol., 24, 2017
7T6M	Cryo-EM structure of TRPV5 in nanodiscs with PI(4,5)P2 at pH6 state 1 Descriptor: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate Authors: Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. Deposit date: 2021-12-14 Release date: 2022-05-04 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
7T6J	Cryo-EM structure of TRPV5 at pH8 in nanodiscs Descriptor: Transient receptor potential cation channel subfamily V member 5 Authors: Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. Deposit date: 2021-12-14 Release date: 2022-05-04 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
7T6K	Cryo-EM structure of TRPV5 at pH6 in nanodiscs Descriptor: Transient receptor potential cation channel subfamily V member 5 Authors: Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. Deposit date: 2021-12-14 Release date: 2022-05-04 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
7T6Q	Cryo-EM structure of TRPV5 T709D with PI(4,5)P2 in nanodiscs Descriptor: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate Authors: Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. Deposit date: 2021-12-14 Release date: 2022-05-04 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
7T6R	Cryo-EM structure of TRPV5 T709D in nanodiscs in the presence of Calmodulin Descriptor: Transient receptor potential cation channel subfamily V member 5 Authors: Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. Deposit date: 2021-12-14 Release date: 2022-05-04 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
7T6P	Cryo-EM structure of TRPV5 T709D in nanodiscs Descriptor: Transient receptor potential cation channel subfamily V member 5 Authors: Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. Deposit date: 2021-12-14 Release date: 2022-05-04 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
7T6L	Cryo-EM structure of TRPV5 at pH5 in nanodiscs Descriptor: Transient receptor potential cation channel subfamily V member 5 Authors: Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. Deposit date: 2021-12-14 Release date: 2022-05-04 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
7T6O	Cryo-EM structure of TRPV5 in nanodiscs at pH6 state 3 Descriptor: Transient receptor potential cation channel subfamily V member 5 Authors: Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. Deposit date: 2021-12-14 Release date: 2022-05-04 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
7T6N	Cryo-EM structure of TRPV5 in nanodiscs at pH6 state 2 Descriptor: Transient receptor potential cation channel subfamily V member 5 Authors: Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. Deposit date: 2021-12-14 Release date: 2022-05-04 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
6MHS	Structure of the human TRPV3 channel in a putative sensitized conformation Descriptor: Transient receptor potential cation channel subfamily V member 3 Authors: Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y. Deposit date: 2018-09-18 Release date: 2018-10-03 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Conformational ensemble of the human TRPV3 ion channel. Nat Commun, 9, 2018
6MHX	Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (2) Descriptor: Transient receptor potential cation channel subfamily V member 3 Authors: Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y. Deposit date: 2018-09-18 Release date: 2018-10-03 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4 Å) Cite: Conformational ensemble of the human TRPV3 ion channel. Nat Commun, 9, 2018
6MHW	Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (1) Descriptor: Transient receptor potential cation channel subfamily V member 3 Authors: Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y. Deposit date: 2018-09-18 Release date: 2018-10-03 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4 Å) Cite: Conformational ensemble of the human TRPV3 ion channel. Nat Commun, 9, 2018
6MHV	Structure of human TRPV3 in the presence of 2-APB in C4 symmetry Descriptor: Transient receptor potential cation channel subfamily V member 3 Authors: Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y. Deposit date: 2018-09-18 Release date: 2018-10-03 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Conformational ensemble of the human TRPV3 ion channel. Nat Commun, 9, 2018
6MHO	Structure of the human TRPV3 channel in the apo conformation Descriptor: Transient receptor potential cation channel subfamily V member 3 Authors: Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y. Deposit date: 2018-09-18 Release date: 2018-10-03 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Conformational ensemble of the human TRPV3 ion channel. Nat Commun, 9, 2018
7UGG	Cryo-EM structure of TRPV3 in complex with the anesthetic dyclonine Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Dyclonine, SODIUM ION, ... Authors: Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. Deposit date: 2022-03-24 Release date: 2022-06-08 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Structural mechanism of TRPV3 channel inhibition by the anesthetic dyclonine. Nat Commun, 13, 2022
8SLX	Rat TRPV2 bound with 1 CBD ligand in nanodiscs Descriptor: SODIUM ION, Transient receptor potential cation channel subfamily V member 2, cannabidiol Authors: Tan, X, Swartz, K.J. Deposit date: 2023-04-24 Release date: 2023-05-31 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.23 Å) Cite: Cannabidiol sensitizes TRPV2 channels to activation by 2-APB. Elife, 12, 2023
8SLY	Rat TRPV2 bound with 2 CBD ligands in nanodiscs Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 2, ... Authors: Tan, X, Swartz, K.J. Deposit date: 2023-04-24 Release date: 2023-05-31 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.32 Å) Cite: Cannabidiol sensitizes TRPV2 channels to activation by 2-APB. Elife, 12, 2023
8FFO	Cryo-EM structure of wildtype rabbit TRPV5 with PI(4,5)P2 in nanodiscs Descriptor: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ERGOSTEROL, Transient receptor potential cation channel subfamily V member 5, ... Authors: De Jesus-Perez, J.J, Moiseenkova-Bell, V.Y. Deposit date: 2022-12-09 Release date: 2023-11-01 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A. Nat Commun, 14, 2023
8FHH	Wildtype rabbit TRPV5 in nanodiscs in the presence of oleoyl coenzyme A, Closed stated Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ERGOSTEROL, Transient receptor potential cation channel subfamily V member 5 Authors: De Jesus-Perez, J.J, Moiseenkova-Bell, V.Y. Deposit date: 2022-12-14 Release date: 2023-11-01 Method: ELECTRON MICROSCOPY (3.09 Å) Cite: Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A. Nat Commun, 14, 2023
8FHI	Wildtype rabbit TRPV5 in nanodiscs in complex with oleoyl coenzyme A, Open stated Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ERGOSTEROL, S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name), ... Authors: De Jesus-Perez, J.J, Moiseenkova-Bell, V.Y. Deposit date: 2022-12-14 Release date: 2023-11-01 Method: ELECTRON MICROSCOPY (3.25 Å) Cite: Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A. Nat Commun, 14, 2023
8FFQ	Wildtype rabbit TRPV5 into nanodiscs in the presence of PI(4,5)P2 and ruthenium red Descriptor: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ERGOSTEROL, Transient receptor potential cation channel subfamily V member 5, ... Authors: De Jesus-Perez, J.J, Fluck, E.C, Pumroy, R.A, Protopopova, A.D, Rocereta, J.A, Moiseenkova-Bell, V.Y. Deposit date: 2022-12-09 Release date: 2024-02-07 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (2.65 Å) Cite: Molecular details of ruthenium red pore block in TRPV channels. Embo Rep., 25, 2024

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