8SRM
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2PIQ
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![BU of 2piq by Molmil](/molmil-images/mine/2piq) | androgen receptor LBD with small molecule | Descriptor: | 3-[(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)METHYL]PHENOL, 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, ... | Authors: | Estebanez-Perpina, E, Arnold, A.A, Baxter, J.D, Webb, P, Guy, R.K, Fletterick, K.R. | Deposit date: | 2007-04-13 | Release date: | 2007-09-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A surface on the androgen receptor that allosterically regulates coactivator binding. Proc.Natl.Acad.Sci.Usa, 104, 2007
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7D0E
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![BU of 7d0e by Molmil](/molmil-images/mine/7d0e) | Crystal structure of FIP200 Claw/p-CCPG1 FIR2 | Descriptor: | 3-(2-hydroxyethyloxy)-2-[2-(2-hydroxyethyloxy)ethoxymethyl]-2-(2-hydroxyethyloxymethyl)propan-1-ol, Cell cycle progression protein 1 FIR2, DI(HYDROXYETHYL)ETHER, ... | Authors: | Zhou, Z.X, Pan, L.F. | Deposit date: | 2020-09-09 | Release date: | 2021-03-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Phosphorylation regulates the binding of autophagy receptors to FIP200 Claw domain for selective autophagy initiation. Nat Commun, 12, 2021
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7CZG
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![BU of 7czg by Molmil](/molmil-images/mine/7czg) | Crystal structure of FIP200 Claw domain apo form | Descriptor: | DI(HYDROXYETHYL)ETHER, RB1-inducible coiled-coil protein 1 | Authors: | Zhou, Z.X, Pan, L.F. | Deposit date: | 2020-09-08 | Release date: | 2021-03-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Phosphorylation regulates the binding of autophagy receptors to FIP200 Claw domain for selective autophagy initiation. Nat Commun, 12, 2021
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7CZM
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![BU of 7czm by Molmil](/molmil-images/mine/7czm) | Crystal structure of FIP200 Claw/p-OPtineurin LIR complex | Descriptor: | CHLORIDE ION, GLYCEROL, Optineurin LIR, ... | Authors: | Zhou, Z.X, Pan, L.F. | Deposit date: | 2020-09-09 | Release date: | 2021-03-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Phosphorylation regulates the binding of autophagy receptors to FIP200 Claw domain for selective autophagy initiation. Nat Commun, 12, 2021
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1H15
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![BU of 1h15 by Molmil](/molmil-images/mine/1h15) | X-ray crystal structure of HLA-DRA1*0101/DRB5*0101 complexed with a peptide from Epstein Barr Virus DNA polymerase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA POLYMERASE, ... | Authors: | Lang, H, Jacobsen, H, Ikemizu, S, Andersson, C, Harlos, K, Madsen, L, Hjorth, P, Sondergaard, L, Svejgaard, A, Wucherpfennig, K, Stuart, D.I, Bell, J.I, Jones, E.Y, Fugger, L. | Deposit date: | 2002-07-02 | Release date: | 2002-10-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | A Functional and Structural Basis for Tcr Cross-Reactivity in Multiple Sclerosis Nat.Immunol., 3, 2002
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3JQO
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![BU of 3jqo by Molmil](/molmil-images/mine/3jqo) | Crystal structure of the outer membrane complex of a type IV secretion system | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, LAURYL DIMETHYLAMINE-N-OXIDE, TraF protein, ... | Authors: | Chandran, V, Fronzes, R, Duquerroy, S, Cronin, N, Navaza, J, Waksman, G. | Deposit date: | 2009-09-07 | Release date: | 2009-12-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the outer membrane complex of a type IV secretion system Nature, 462, 2009
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3D2U
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![BU of 3d2u by Molmil](/molmil-images/mine/3d2u) | Structure of UL18, a Peptide-Binding Viral MHC Mimic, Bound to a Host Inhibitory Receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Actin, Beta-2-microglobulin, ... | Authors: | Yang, Z, Bjorkman, P.J. | Deposit date: | 2008-05-08 | Release date: | 2008-07-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Structure of UL18, a peptide-binding viral MHC mimic, bound to a host inhibitory receptor Proc.Natl.Acad.Sci.Usa, 105, 2008
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6F1Z
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![BU of 6f1z by Molmil](/molmil-images/mine/6f1z) | Roadblock-1 region of the dynein tail/dynactin/BICDR1 complex | Descriptor: | Cytoplasmic dynein 1 intermediate chain 2, Dynein light chain roadblock-type 1 | Authors: | Urnavicius, L, Lau, C.K, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. | Deposit date: | 2017-11-23 | Release date: | 2018-01-17 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM shows how dynactin recruits two dyneins for faster movement. Nature, 554, 2018
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9B7B
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![BU of 9b7b by Molmil](/molmil-images/mine/9b7b) | |
3S4S
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![BU of 3s4s by Molmil](/molmil-images/mine/3s4s) | Crystal structure of CD4 mutant bound to HLA-DR1 | Descriptor: | GLYCEROL, HLA class II histocompatibility antigen, DR alpha chain, ... | Authors: | Li, Y. | Deposit date: | 2011-05-20 | Release date: | 2011-09-21 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex. Proc.Natl.Acad.Sci.USA, 108, 2011
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3T0E
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![BU of 3t0e by Molmil](/molmil-images/mine/3t0e) | Crystal structure of a complete ternary complex of T cell receptor, peptide-MHC and CD4 | Descriptor: | HLA class II histocompatibility antigen, DR alpha chain, DRB1-4 beta chain, ... | Authors: | Yin, Y, Mariuzza, R.A. | Deposit date: | 2011-07-20 | Release date: | 2012-03-07 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4. Proc.Natl.Acad.Sci.USA, 109, 2012
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7O3T
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![BU of 7o3t by Molmil](/molmil-images/mine/7o3t) | I-layer structure (TrwF/VirB9NTD, TrwE/VirB10NTD) of the outer membrane core complex from the fully-assembled R388 type IV secretion system determined by cryo-EM. | Descriptor: | TrwE protein, TrwF protein | Authors: | Mace, K, Vadakkepat, A.K, Lukoyanova, N, Waksman, G. | Deposit date: | 2021-04-03 | Release date: | 2022-06-22 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structure of a type IV secretion system. Nature, 607, 2022
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4LWZ
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![BU of 4lwz by Molmil](/molmil-images/mine/4lwz) | Crystal structure of Myo5b globular tail domain in complex with inactive Rab11a | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-11A, ... | Authors: | Pylypenko, O, Attanda, W, Gauquelin, C, Houdusse, A. | Deposit date: | 2013-07-29 | Release date: | 2013-11-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural basis of myosin V Rab GTPase-dependent cargo recognition. Proc.Natl.Acad.Sci.USA, 110, 2013
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8EUQ
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![BU of 8euq by Molmil](/molmil-images/mine/8euq) | Crystal structure of HLA-DRA*01:01/HLA-DRB1*04:01 in complex with c44H10 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, ... | Authors: | Kassardjian, A, Julien, J.-P. | Deposit date: | 2022-10-19 | Release date: | 2023-04-19 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses. Cell Rep, 42, 2023
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3PGC
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![BU of 3pgc by Molmil](/molmil-images/mine/3pgc) | Crystal Structure of HLA-DR1 with CLIP106-120, flipped peptide orientation | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, HLA class II histocompatibility antigen gamma chain, ... | Authors: | Gunther, S, Schlundt, A, Sticht, J, Roske, Y, Heinemann, U, Wiesmuller, K.-H, Jung, G, Falk, K, Rotzschke, O, Freund, C. | Deposit date: | 2010-11-01 | Release date: | 2010-12-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | Bidirectional binding of invariant chain peptides to an MHC class II molecule. Proc.Natl.Acad.Sci.USA, 107, 2010
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3PGD
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![BU of 3pgd by Molmil](/molmil-images/mine/3pgd) | Crystal Structure of HLA-DR1 with CLIP106-120, canonical peptide orientation | Descriptor: | HLA class II histocompatibility antigen gamma chain, HLA class II histocompatibility antigen, DR alpha chain, ... | Authors: | Gunther, S, Schlundt, A, Sticht, J, Roske, Y, Heinemann, U, Wiesmuller, K.-H, Jung, G, Falk, K, Rotzschke, O, Freund, C. | Deposit date: | 2010-11-01 | Release date: | 2010-12-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Bidirectional binding of invariant chain peptides to an MHC class II molecule. Proc.Natl.Acad.Sci.USA, 107, 2010
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3PDO
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![BU of 3pdo by Molmil](/molmil-images/mine/3pdo) | Crystal Structure of HLA-DR1 with CLIP102-120 | Descriptor: | FORMIC ACID, GLYCEROL, HLA class II histocompatibility antigen gamma chain, ... | Authors: | Gunther, S, Schlundt, A, Sticht, J, Roske, Y, Heinemann, U, Wiesmuller, K.-H, Jung, G, Falk, K, Rotzschke, O, Freund, C. | Deposit date: | 2010-10-23 | Release date: | 2010-12-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Bidirectional binding of invariant chain peptides to an MHC class II molecule. Proc.Natl.Acad.Sci.USA, 107, 2010
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3L6F
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1AQD
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![BU of 1aqd by Molmil](/molmil-images/mine/1aqd) | |
5KTF
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![BU of 5ktf by Molmil](/molmil-images/mine/5ktf) | Structure of the C-terminal transmembrane domain of scavenger receptor BI (SR-BI) | Descriptor: | Scavenger receptor class B member 1 | Authors: | Chadwick, A.C, Peterson, F.C, Volkman, B.F, Sahoo, D. | Deposit date: | 2016-07-11 | Release date: | 2017-03-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR Structure of the C-Terminal Transmembrane Domain of the HDL Receptor, SR-BI, and a Functionally Relevant Leucine Zipper Motif. Structure, 25, 2017
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7Z8F
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![BU of 7z8f by Molmil](/molmil-images/mine/7z8f) | |
4X5X
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![BU of 4x5x by Molmil](/molmil-images/mine/4x5x) | |
8HSV
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![BU of 8hsv by Molmil](/molmil-images/mine/8hsv) | The structure of rat beta-arrestin1 in complex with a rat Mdm2 peptide | Descriptor: | Beta-arrestin-1, SULFATE ION, peptide from E3 ubiquitin-protein ligase Mdm2 | Authors: | Yun, Y, Yoon, H.J, Choi, Y, Lee, H.H. | Deposit date: | 2022-12-20 | Release date: | 2023-07-19 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | GPCR targeting of E3 ubiquitin ligase MDM2 by inactive beta-arrestin. Proc.Natl.Acad.Sci.USA, 120, 2023
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4OV5
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![BU of 4ov5 by Molmil](/molmil-images/mine/4ov5) | Structure of HLA-DR1 with a bound peptide with non-optimal alanine in the P1 pocket | Descriptor: | HLA class I histocompatibility antigen, A-2 alpha chain, HLA class II histocompatibility antigen, ... | Authors: | Trenh, P, Yin, L, Stern, L.J. | Deposit date: | 2014-02-20 | Release date: | 2014-07-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.199 Å) | Cite: | Susceptibility to HLA-DM Protein Is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with Peptide. J.Biol.Chem., 289, 2014
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