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4PMI
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BU of 4pmi by Molmil
Crystal structure of Rev and Rev-response-element RNA complex
Descriptor: PHOSPHATE ION, Protein Rev, Rev-Response-Element RNA
Authors:Jayaraman, B, Crosby, D.C, Homer, C, Ribeiro, I, Mavor, D, Frankel, A.D.
Deposit date:2014-05-21
Release date:2014-12-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:RNA-directed remodeling of the HIV-1 protein Rev orchestrates assembly of the Rev-Rev response element complex.
Elife, 4, 2014
2HKU
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BU of 2hku by Molmil
Structural Genomics, the crystal structure of a putative transcriptional regulator from Rhodococcus sp. RHA1
Descriptor: 1,2-ETHANEDIOL, A putative transcriptional regulator, TETRAETHYLENE GLYCOL
Authors:Tan, K, Evdokimova, E, Kagan, O, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2006-07-05
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of a transcriptional regulator from Rhodococcus sp. RHA1
To be Published
6SNJ
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BU of 6snj by Molmil
Solution structure of the FUS/TLS RNA recognition motif in complex with U1 snRNA stem loop III
Descriptor: RNA-binding protein FUS, U1 snRNA stem loop III, RNA (28-MER)
Authors:Campagne, S, Allain, F.H.
Deposit date:2019-08-26
Release date:2020-10-28
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis.
Nat Commun, 11, 2020
3U85
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BU of 3u85 by Molmil
Crystal structure of human menin in complex with MLL1
Descriptor: Histone-lysine N-methyltransferase 2A, Menin
Authors:Huang, J, Wan, B, Lei, M.
Deposit date:2011-10-15
Release date:2012-02-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature, 482, 2012
4RGR
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BU of 4rgr by Molmil
Crystal Structure of Putative MarR Family Transcriptional Regulator HcaR from Acinetobacter sp. ADP
Descriptor: 4'-HYDROXYCINNAMIC ACID, GLYCEROL, Repressor protein, ...
Authors:Kim, Y, Joachimiak, G, Bigelow, L, Cobb, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2014-09-30
Release date:2015-03-04
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:Crystal Structure of Putative MarR Family Transcriptional Regulator HcaR from Acinetobacter sp. ADP
To be Published, 2014
4RGS
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BU of 4rgs by Molmil
Crystal Structure of Putative MarR Family Transcriptional Regulator HcaR from Acinetobacter sp. ADP complexed with Vanilin
Descriptor: 4-hydroxy-3-methoxybenzaldehyde, GLYCEROL, Repressor protein, ...
Authors:Kim, Y, Joachimiak, G, Bigelow, L, Cobb, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2014-09-30
Release date:2015-03-04
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Crystal Structure of Putative MarR Family Transcriptional Regulator HcaR from Acinetobacter sp. ADP complexed with Vanilin
To be Published, 2014
4RGU
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BU of 4rgu by Molmil
Crystal Structure of Putative MarR Family Transcriptional Regulator HcaR from Acinetobacter sp. ADP complexed with ferulic acid
Descriptor: 3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACID, CHLORIDE ION, GLYCEROL, ...
Authors:Kim, Y, Joachimiak, G, Bigelow, L, Cobb, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2014-09-30
Release date:2015-03-04
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.891 Å)
Cite:Crystal Structure of Putative MarR Family Transcriptional Regulator HcaR from Acinetobacter sp. ADP complexed with ferulic acid
To be Published, 2014
4RGX
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BU of 4rgx by Molmil
Crystal Structure of Putative MarR Family Transcriptional Regulator HcaR from Acinetobacter sp. ADP complexed with 3,4-dihydroxy bezoic acid
Descriptor: 1,2-ETHANEDIOL, 3,4-DIHYDROXYBENZOIC ACID, CHLORIDE ION, ...
Authors:Kim, Y, Joachimiak, G, Bigelow, L, Cobb, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2014-09-30
Release date:2015-03-04
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:Crystal Structure of Putative MarR Family Transcriptional Regulator HcaR from Acinetobacter sp. ADP complexed with 3,4-dihydroxy bezoic acid
To be Published, 2014
2EWN
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BU of 2ewn by Molmil
Ecoli Biotin Repressor with co-repressor analog
Descriptor: ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHYL 5-((3AS,4S,6AR)-2-OXO-HEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL)PENTYL HYDROGEN PHOSPHATE, BirA bifunctional protein
Authors:Wood, Z.A, Weaver, L.H, Matthews, B.W.
Deposit date:2005-11-04
Release date:2006-02-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Co-repressor Induced Order and Biotin Repressor Dimerization: A Case for Divergent Followed by Convergent Evolution.
J.Mol.Biol., 357, 2006
4TL1
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BU of 4tl1 by Molmil
GCN4-p1 with mutation to 1-Aminocyclohexanecarboxylic acid at residue 10
Descriptor: General control protein GCN4, ISOPROPYL ALCOHOL
Authors:Tavenor, N.A, Silva, K.I, Saxena, S, Horne, W.S.
Deposit date:2014-05-28
Release date:2014-08-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Origins of Structural Flexibility in Protein-Based Supramolecular Polymers Revealed by DEER Spectroscopy.
J.Phys.Chem.B, 118, 2014
5UR2
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BU of 5ur2 by Molmil
Crystal structure of proline utilization A (PutA) from Bdellovibrio bacteriovorus inactivated by N-propargylglycine
Descriptor: Bifunctional protein PutA, N-propargylglycine-modified flavin adenine dinucleotide
Authors:Tanner, J.J.
Deposit date:2017-02-09
Release date:2017-08-02
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Biophysical investigation of type A PutAs reveals a conserved core oligomeric structure.
FEBS J., 284, 2017
5YVG
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BU of 5yvg by Molmil
Crystal structure of Karyopherin beta2 in complex with FUS(full length)
Descriptor: RNA-binding protein FUS, Transportin-1
Authors:Yoshizawa, T, Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-11-25
Release date:2018-05-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (4.05 Å)
Cite:Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Cell, 173, 2018
4NQF
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BU of 4nqf by Molmil
Crystal structure of HEPN domain protein
Descriptor: Nucleotidyltransferase
Authors:Padavannil, A, Jobichen, C, Sivaraman, J.
Deposit date:2013-11-25
Release date:2014-03-26
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Dimerization of VirD2 Binding Protein Is Essential for Agrobacterium Induced Tumor Formation in Plants
Plos Pathog., 10, 2014
7W2Q
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BU of 7w2q by Molmil
Crystal structure of Pseudomonas aeruginosa transcriptional regulator PvrA in the narrow conformation
Descriptor: Probable transcriptional regulator
Authors:Bao, R, Zhu, Y.B.
Deposit date:2021-11-24
Release date:2022-11-30
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Pseudomonas aeruginosa PvrA cooperatively binds to multiple pseudo-palindromic sites to hyper stimulate target gene expression
To be published
7W2O
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BU of 7w2o by Molmil
Crystal structure of Pseudomonas aeruginosa transcriptional regulator PvrA in the wide conformation
Descriptor: Probable transcriptional regulator
Authors:Bao, R, Zhu, Y.B.
Deposit date:2021-11-24
Release date:2022-11-30
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Pseudomonas aeruginosa PvrA cooperatively binds to multiple pseudo-palindromic sites to hyper stimulate target gene expression
To be published
3U86
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BU of 3u86 by Molmil
Crystal structure of human menin in complex with JunD
Descriptor: Menin, Transcription factor jun-D
Authors:Huang, J, Wan, B, Lei, M.
Deposit date:2011-10-15
Release date:2012-02-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.843 Å)
Cite:The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature, 482, 2012
2JJ3
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BU of 2jj3 by Molmil
Estrogen receptor beta ligand binding domain in complex with a Benzopyran agonist
Descriptor: (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL, ESTROGEN RECEPTOR BETA
Authors:Norman, B.H, Richardson, T.I, Dodge, J.A, Pfeifer, L.A, Durst, G.L, Wang, Y, Durbin, J.D, Krishnan, V, Dinn, S.R, Liu, S, Reilly, J.E, Ryter, K.T.
Deposit date:2007-07-03
Release date:2007-08-07
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Benzopyrans as Selective Estrogen Receptor Beta Agonists (Serbas). Part 4: Functionalization of the Benzopyran A-Ring.
Bioorg.Med.Chem.Lett., 17, 2007
2JLE
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BU of 2jle by Molmil
Novel indazole nnrtis created using molecular template hybridization based on crystallographic overlays
Descriptor: 5-[(5-fluoro-3-methyl-1H-indazol-4-yl)oxy]benzene-1,3-dicarbonitrile, REVERSE TRANSCRIPTASE/RNASEH
Authors:Jones, L.H, Allan, G, Barba, O, Burt, C, Corbau, R, Dupont, T, Irving, S, Mowbray, C.E, Phillips, C, Swain, N.A, Webster, R, Westby, M.
Deposit date:2008-09-08
Release date:2009-08-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Novel Indazole Non-Nucleoside Reverse Transcriptase Inhibitors Using Molecular Hybridization Based on Crystallographic Overlays.
J.Med.Chem., 52, 2009
2QWT
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BU of 2qwt by Molmil
Crystal structure of the TetR transcription regulatory protein from Mycobacterium vanbaalenii
Descriptor: Transcriptional regulator, TetR family
Authors:Bonanno, J.B, Freeman, J, Bain, K.T, Adams, J, Romero, R, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-08-10
Release date:2007-08-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the TetR transcription regulatory protein from Mycobacterium vanbaalenii.
To be Published
1WJV
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BU of 1wjv by Molmil
Solution structure of the N-terminal zinc finger domain of mouse cell growth regulating nucleolar protein LYAR
Descriptor: Cell growth regulating nucleolar protein LYAR, ZINC ION
Authors:Yoneyama, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-05-29
Release date:2004-11-29
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the N-terminal zinc finger domain of mouse cell growth regulating nucleolar protein LYAR
To be Published
3U88
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BU of 3u88 by Molmil
Crystal structure of human menin in complex with MLL1 and LEDGF
Descriptor: (4beta,8alpha,9R)-6'-methoxy-10,11-dihydrocinchonan-9-ol, CHOLIC ACID, GLYOXYLIC ACID, ...
Authors:Huang, J, Wan, B, Lei, M.
Deposit date:2011-10-16
Release date:2012-02-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature, 482, 2012
5UX5
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BU of 5ux5 by Molmil
Structure of Proline Utilization A (PutA) from Corynebacterium freiburgense
Descriptor: BIFUNCTIONAL PROTEIN Proline utilization A (PutA), FLAVIN-ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Tanner, J.J.
Deposit date:2017-02-22
Release date:2017-04-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and characterization of a class 3B proline utilization A: Ligand-induced dimerization and importance of the C-terminal domain for catalysis.
J. Biol. Chem., 292, 2017
3U84
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BU of 3u84 by Molmil
Crystal Structure of Human Menin
Descriptor: Menin
Authors:Huang, J, Wan, B, Lei, M.
Deposit date:2011-10-15
Release date:2012-02-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature, 482, 2012
1NJQ
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BU of 1njq by Molmil
NMR structure of the single QALGGH zinc finger domain from Arabidopsis thaliana SUPERMAN protein
Descriptor: ZINC ION, superman protein
Authors:Isernia, C, Bucci, E, Leone, M, Zaccaro, L, Di Lello, P, Digilio, G, Esposito, S, Saviano, M, Di Blasio, B, Pedone, C, Pedone, P.V, Fattorusso, R.
Deposit date:2003-01-02
Release date:2003-03-04
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:NMR Structure of the Single QALGGH Zinc Finger Domain from the Arabidopsis thaliana SUPERMAN Protein.
Chembiochem, 4, 2003
2K6X
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BU of 2k6x by Molmil
Autoregulation of a Group 1 Bacterial Sigma Factor Involves the Formation of a Region 1.1- Induced Compacted Structure
Descriptor: RNA polymerase sigma factor rpoD
Authors:Schwartz, E.C, Shekhtman, A, Dutta, K, Pratt, M.R, Cowburn, D, Darst, S, Muir, T.W.
Deposit date:2008-07-28
Release date:2008-10-28
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Autoregulation of a Group 1 Bacterial Sigma Factor Involves the Formation of a Region 1.1 - Induced Compacted Structure
Chem.Biol., 15, 2008

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