PDB: 325 resultsInfo pagesStatus searchChemie searchBIRD

---

4G3G	Crystal structure of murine NF-kappaB inducing kinase (NIK) V408L bound to a 2-(aminothiazolyl)phenol (cmp3) Descriptor: 4-fluoro-2-{[4-(pyridin-4-yl)-1,3-thiazol-2-yl]amino}phenol, NF-kappa-beta-inducing kinase Authors: Hymowitz, S. Deposit date: 2012-07-13 Release date: 2012-08-08 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site. Structure, 20, 2012
4G3E	Crystal structure of murine NF-kappaB inducing kinase (NIK) bound to a 6-alkynylindoline (cmp1) Descriptor: (2R)-4-[1-(2-amino-5-chloropyrimidin-4-yl)-2,3-dihydro-1H-indol-6-yl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol, NF-kappa-beta-inducing kinase, SULFATE ION Authors: Hymowitz, S.G, de Leon-Boenig, G. Deposit date: 2012-07-13 Release date: 2012-08-15 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site. Structure, 20, 2012
4GAW	Crystal structure of active human granzyme H Descriptor: CHLORIDE ION, Granzyme H, SULFATE ION Authors: Wang, L, Li, Q, Wu, L, Zhang, K, Tong, L, Sun, F, Fan, Z. Deposit date: 2012-07-25 Release date: 2013-01-16 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3 Å) Cite: Identification of SERPINB1 as a physiological inhibitor of human granzyme H J.Immunol., 190, 2013
4GA7	Crystal structure of human serpinB1 mutant Descriptor: Leukocyte elastase inhibitor Authors: Wang, L, Li, Q, Wu, L, Zhang, K, Tong, L, Sun, F, Fan, Z. Deposit date: 2012-07-25 Release date: 2013-01-16 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Identification of SERPINB1 as a physiological inhibitor of human granzyme H J.Immunol., 190, 2013
4FWE	Native structure of LSD2 /AOF1/KDM1b in spacegroup of C2221 at 2.13A Descriptor: CITRATE ANION, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1B, ... Authors: Zhang, Q, Chen, Z. Deposit date: 2012-07-01 Release date: 2013-01-16 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.13 Å) Cite: Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b Cell Res., 23, 2013
4G3D	Crystal structure of human NF-kappaB inducing kinase (NIK) Descriptor: MAGNESIUM ION, NF-kappa-beta-inducing kinase Authors: Hymowitz, S.G, de Leon-Boenig, G. Deposit date: 2012-07-13 Release date: 2012-08-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.9 Å) Cite: The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site. Structure, 20, 2012
4IGN	2.32 Angstrom X-ray Crystal structure of R47A mutant of human ACMSD Descriptor: 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, ZINC ION Authors: Liu, F, Liu, A. Deposit date: 2012-12-17 Release date: 2014-05-07 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.329 Å) Cite: Human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD): A structural and mechanistic unveiling. Proteins, 83, 2015
4F99	Human CDC7 kinase in complex with DBF4 and nucleotide Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division cycle 7-related protein kinase, MAGNESIUM ION, ... Authors: Hughes, S, Cherepanov, P. Deposit date: 2012-05-18 Release date: 2012-10-31 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.33 Å) Cite: Crystal structure of human CDC7 kinase in complex with its activator DBF4. Nat.Struct.Mol.Biol., 19, 2012
4JJ0	Crystal structure of MamP Descriptor: GLYCEROL, HEME C, MamP Authors: Siponen, M, Pignol, D, Arnoux, P. Deposit date: 2013-03-07 Release date: 2013-10-09 Last modified: 2013-11-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural insight into magnetochrome-mediated magnetite biomineralization. Nature, 502, 2013
4LCQ	The crystal structure of di-Zn dihydropyrimidinase in complex with NCBI Descriptor: (2S)-3-(carbamoylamino)-2-methylpropanoic acid, ZINC ION, dihydropyrimidinase Authors: Hsieh, Y.C, Chen, M.C, Hsu, C.C, Chan, S.I, Yang, Y.S, Chen, C.J. Deposit date: 2013-06-22 Release date: 2013-09-18 Last modified: 2014-02-12 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Crystal structures of vertebrate dihydropyrimidinase and complexes from Tetraodon nigroviridis with lysine carbamylation: metal and structural requirements for post-translational modification and function. J.Biol.Chem., 288, 2013
4F9B	Human CDC7 kinase in complex with DBF4 and PHA767491 Descriptor: 2-(pyridin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one, Cell division cycle 7-related protein kinase, Protein DBF4 homolog A, ... Authors: Hughes, S, Cherepanov, P. Deposit date: 2012-05-18 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of human CDC7 kinase in complex with its activator DBF4. Nat.Struct.Mol.Biol., 19, 2012
4H5E	Crystal structure of human FPPS in ternary complex with YS0470 and isopentenyl pyrophosphate Descriptor: Farnesyl pyrophosphate synthase, ISOPENTYL PYROPHOSPHATE, MAGNESIUM ION, ... Authors: Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M. Deposit date: 2012-09-18 Release date: 2012-12-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. Bmc Struct.Biol., 12, 2012
4LCS	The crystal structure of di-Zn dihydropyrimidinase in complex with hydantoin Descriptor: Chromosome 8 SCAF14545, whole genome shotgun sequence, ZINC ION, ... Authors: Hsieh, Y.C, Chen, M.C, Hsu, C.C, Chan, S.I, Yang, Y.S. Deposit date: 2013-06-23 Release date: 2013-09-18 Last modified: 2014-02-12 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structures of vertebrate dihydropyrimidinase and complexes from Tetraodon nigroviridis with lysine carbamylation: metal and structural requirements for post-translational modification and function. J.Biol.Chem., 288, 2013
4F9A	Human CDC7 kinase in complex with DBF4 and nucleotide Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division cycle 7-related protein kinase, MAGNESIUM ION, ... Authors: Hughes, S, Cherepanov, P. Deposit date: 2012-05-18 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.17 Å) Cite: Crystal structure of human CDC7 kinase in complex with its activator DBF4. Nat.Struct.Mol.Biol., 19, 2012
4GOB	Low pH Crystal Structure of a reconstructed Kaede-type Red Fluorescent Protein, Least Evolved Ancestor (LEA) Descriptor: Kaede-type Fluorescent Protein Authors: Kim, H, Grunkemeyer, T.J, Chen, L, Fromme, R, Wachter, R.M. Deposit date: 2012-08-19 Release date: 2013-07-31 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Acid-base catalysis and crystal structures of a least evolved ancestral GFP-like protein undergoing green-to-red photoconversion. Biochemistry, 52, 2013
4GPZ	Crystal structure of human B type phosphoglycerate mutase H11 phosphorylated form Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Phosphoglycerate mutase 1 Authors: He, C, Zhou, L, Zhang, L. Deposit date: 2012-08-22 Release date: 2013-05-22 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation. Nat Commun, 4, 2013
4JDD	14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface Descriptor: 14-3-3 protein sigma, Estrogen receptor Peptide, FUSICOCCIN Authors: Bier, D, Ottmann, C. Deposit date: 2013-02-25 Release date: 2013-05-15 Last modified: 2017-06-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface. Proc. Natl. Acad. Sci. U.S.A., 110, 2013
4LCR	The crystal structure of di-Zn dihydropyrimidinase in complex with NCBA Descriptor: Chromosome 8 SCAF14545, whole genome shotgun sequence, N-(AMINOCARBONYL)-BETA-ALANINE, ... Authors: Hsieh, Y.C, Chen, M.C, Hsu, C.C, Chan, S.I, Yang, Y.S, Chen, C.J. Deposit date: 2013-06-22 Release date: 2013-09-18 Last modified: 2014-02-12 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structures of vertebrate dihydropyrimidinase and complexes from Tetraodon nigroviridis with lysine carbamylation: metal and structural requirements for post-translational modification and function. J.Biol.Chem., 288, 2013
4LDU	Crystal structure of the DNA binding domain of Arabidopsis thaliana auxin response factor 5 Descriptor: Auxin response factor 5, CHLORIDE ION Authors: Boer, D.R, Freire-Rios, A, van den Berg, W.M.A, Weijers, D, Coll, M. Deposit date: 2013-06-25 Release date: 2014-02-12 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structural Basis for DNA Binding Specificity by the Auxin-Dependent ARF Transcription Factors. Cell(Cambridge,Mass.), 156, 2014
4H5D	Crystal structure of human FPPS in ternary complex with YS0470 and inorganic pyrophosphate Descriptor: Farnesyl pyrophosphate synthase, MAGNESIUM ION, PYROPHOSPHATE 2-, ... Authors: Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M. Deposit date: 2012-09-18 Release date: 2012-12-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. Bmc Struct.Biol., 12, 2012
4KWI	The crystal structure of angucycline C-6 ketoreductase LanV with bound NADP and 11-deoxy-6-oxylandomycinone Descriptor: 1,8-dihydroxy-3-methyltetraphene-6,7,12(5H)-trione, DI(HYDROXYETHYL)ETHER, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Paananen, P, Patrikainen, P, Mantsala, P, Niemi, J, Niiranen, L, Metsa-Ketela, M. Deposit date: 2013-05-24 Release date: 2013-07-31 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural and functional analysis of angucycline C-6 ketoreductase LanV involved in landomycin biosynthesis. Biochemistry, 52, 2013
4JJ3	Crystal structure of MamP soaked with iron(II) Descriptor: HEME C, MamP Authors: Siponen, M, Pignol, D, Arnoux, P. Deposit date: 2013-03-07 Release date: 2013-10-09 Last modified: 2018-10-31 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural insight into magnetochrome-mediated magnetite biomineralization. Nature, 502, 2013
4JC3	14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface Descriptor: 14-3-3 protein sigma, Estrogen receptor Peptide, MAGNESIUM ION Authors: Bier, D, Ottmann, C. Deposit date: 2013-02-21 Release date: 2013-05-15 Last modified: 2017-06-07 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface. Proc. Natl. Acad. Sci. U.S.A., 110, 2013
4H5C	Crystal structure of human FPPS in ternary complex with YS0470 and inorganic phosphate Descriptor: Farnesyl pyrophosphate synthase, MAGNESIUM ION, PHOSPHATE ION, ... Authors: Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M. Deposit date: 2012-09-18 Release date: 2012-12-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. Bmc Struct.Biol., 12, 2012
4F9C	Human CDC7 kinase in complex with DBF4 and XL413 Descriptor: 8-chloro-2-[(2S)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one, Cell division cycle 7-related protein kinase, Protein DBF4 homolog A, ... Authors: Hughes, S, Cherepanov, P. Deposit date: 2012-05-18 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Crystal structure of human CDC7 kinase in complex with its activator DBF4. Nat.Struct.Mol.Biol., 19, 2012

<345678910111213>