4HLY

The complex crystal structure of the DNA binding domain of vIRF-1 from the oncogenic KSHV with DNA

Summary for 4HLY

• Entry DOI: 10.2210/pdb4hly/pdb
• Descriptor: K9, 5'-D(*GP*CP*GP*TP*CP*GP*AP*GP*AP*CP*GP*C)-3' (3 entities in total)
• Functional Keywords: helix-turn-helix, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Human herpesvirus 8 (HHV-8); More
• Total number of polymer chains: 4
• Total formula weight: 37995.77

Authors

Hew, K.,Venkatachalam, R. (deposition date: 2012-10-17, release date: 2013-03-13, Last modification date: 2024-03-20)

• Primary citation: Hew, K.,Dahlroth, S.L.,Venkatachalam, R.,Nasertorabi, F.,Lim, B.T.,Cornvik, T.,Nordlund, P.; The crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factor.; Nucleic Acids Res., 41:4295-4306, 2013; PubMed: 23435230; DOI: 10.1093/nar/gkt082

Experimental method

X-RAY DIFFRACTION (1.48 Å)