4HLY

The complex crystal structure of the DNA binding domain of vIRF-1 from the oncogenic KSHV with DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	K9	polymer	132	15309.5	2	UniProt (Q77Q82) Pfam (PF00605) UniProt (by SIFTS) (F5HF68)	Human herpesvirus 8 (HHV-8)	Latent viral interferon regulatory factor, Lytic viral interferon regulatory factor, ORF K9, VIRF-1 protein
2	C, D (C, D)	5'-D(*GP*CP*GP*TP*CP*GP*AP*GP*AP*CP*GP*C)-3'	polymer	12	3688.4	2		synthetic construct
3	E, F, G, H (A, B, C, D)	water	water		18.0	232	Chemie (HOH)

Sequence modifications

A, B: 2 - 110 (UniProt: Q77Q82)

PDB	External Database	Details
Met -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
Ser -14	-	expression tag
Ser -13	-	expression tag
Gly -12	-	expression tag
Val -11	-	expression tag
Asp -10	-	expression tag
Leu -9	-	expression tag
Gly -8	-	expression tag
Thr -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Ser 0	-	expression tag
Met 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	37995.8
All*	Total formula weight	37995.8

*Water molecules are not included.