4IGN

2.32 Angstrom X-ray Crystal structure of R47A mutant of human ACMSD

Summary for 4IGN

• Entry DOI: 10.2210/pdb4ign/pdb
• Descriptor: 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, ZINC ION (3 entities in total)
• Functional Keywords: tim barrel, neurological disorder, zinc-dependent decarboxylase, kynurenine pathway, lyase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 6
• Total formula weight: 225179.55

Authors

Liu, F.,Liu, A. (deposition date: 2012-12-17, release date: 2014-05-07, Last modification date: 2024-02-28)

• Primary citation: Huo, L.,Liu, F.,Iwaki, H.,Li, T.,Hasegawa, Y.,Liu, A.; Human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD): A structural and mechanistic unveiling.; Proteins, 83:178-187, 2015; PubMed: 25392945; DOI: 10.1002/prot.24722

Experimental method

X-RAY DIFFRACTION (2.329 Å)