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PDB: 1477 results

4V6Z
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E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in classic pre-translocation state (pre1b)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V7D
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Structure of the Ribosome with Elongation Factor G Trapped in the Pre-Translocation State (pre-translocation 70S*tRNA*EF-G structure)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Brilot, A.F, Korostelev, A.A, Ermolenko, D.N, Grigorieff, N.
Deposit date:2013-11-21
Release date:2014-07-09
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Structure of the ribosome with elongation factor G trapped in the pretranslocation state.
Proc.Natl.Acad.Sci.USA, 110, 2013
4V6F
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Elongation complex of the 70S ribosome with three tRNAs and mRNA.
Descriptor: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 23S RRNA, ...
Authors:Jenner, L.B, Yusupova, G, Yusupov, M.
Deposit date:2009-07-09
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural aspects of messenger RNA reading frame maintenance by the ribosome.
Nat.Struct.Mol.Biol., 17, 2010
4V7U
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Crystal structure of the E. coli ribosome bound to erythromycin.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D.
Deposit date:2010-08-15
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.
Proc.Natl.Acad.Sci.USA, 107, 2010
4V8B
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Crystal structure analysis of ribosomal decoding (near-cognate tRNA-leu complex).
Descriptor: 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2011-12-06
Release date:2014-07-09
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:A new understanding of the decoding principle on the ribosome.
Nature, 484, 2012
4V77
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E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in intermediate post-translocation state (post2b)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (17 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V9N
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Crystal structure of the 70S ribosome bound with the Q253P mutant of release factor RF2.
Descriptor: 16S rRNA (1504-MER), 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Santos, N, Zhu, J, Donohue, J.P, Korostelev, A.A, Noller, H.F.
Deposit date:2013-04-26
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal Structure of the 70S Ribosome Bound with the Q253P Mutant Form of Release Factor RF2.
Structure, 21, 2013
4V7K
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Structure of RelE nuclease bound to the 70S ribosome (postcleavage state)
Descriptor: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:Neubauer, C, Gao, Y.-G, Andersen, K.R, Dunham, C.M, Kelley, A.C, Hentschel, J, Gerdes, K, Ramakrishnan, V, Brodersen, D.E.
Deposit date:2009-11-02
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE.
Cell(Cambridge,Mass.), 139, 2009
4V8Q
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Complex of SmpB, a tmRNA fragment and EF-Tu-GDP-Kirromycin with the 70S ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Neubauer, C, Gillet, R, Kelley, A.C, Ramakrishnan, V.
Deposit date:2011-12-10
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Decoding in the absence of a codon by tmRNA and SmpB in the ribosome.
Science, 335, 2012
4V4X
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Crystal structure of the 70S Thermus thermophilus ribosome showing how the 16S 3'-end mimicks mRNA E and P codons.
Descriptor: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Jenner, L, Yusupova, G, Rees, B, Moras, D, Yusupov, M.
Deposit date:2006-06-27
Release date:2014-07-09
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (5 Å)
Cite:Structural basis for messenger RNA movement on the ribosome.
Nature, 444, 2006
4V5B
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Structure of PDF binding helix in complex with the ribosome.
Descriptor: 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Bingel-Erlenmeyer, R, Kohler, R, Kramer, G, Sandikci, A, Antolic, S, Maier, T, Schaffitzel, C, Wiedmann, B, Bukau, B, Ban, N.
Deposit date:2007-11-22
Release date:2014-07-09
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.74 Å)
Cite:A Peptide Deformylase-Ribosome Complex Reveals Mechanism of Nascent Chain Processing.
Nature, 452, 2008
4V5P
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The crystal structure of EF-Tu and A9C-tRNA-Trp bound to a near- cognate codon on the 70S ribosome
Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V.
Deposit date:2010-12-07
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Nat.Struct.Mol.Biol., 18, 2011
4V9I
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Crystal structure of thermus thermophilus 70S in complex with tRNAs and mRNA containing a pseudouridine in a stop codon
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S Ribosomal protein S10, ...
Authors:Fernandez, I.S, Ng, C.L, Kelley, A.C, Guowei, W, Yu, Y.T, Ramakrishnan, V.
Deposit date:2013-04-04
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
4V6A
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Structure of EF-P bound to the 70S ribosome.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Stanley, R.E, Blaha, G.
Deposit date:2009-06-15
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Formation of the first peptide bond: the structure of EF-P bound to the 70S ribosome.
Science, 325, 2009
4V6S
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Structural characterization of mRNA-tRNA translocation intermediates (class 3 of the six classes)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J.
Deposit date:2011-12-09
Release date:2014-07-09
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (13.1 Å)
Cite:Structural characterization of mRNA-tRNA translocation intermediates.
Proc.Natl.Acad.Sci.USA, 109, 2012
4V79
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E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in intermediate post-translocation state (post3b)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V83
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Crystal structure of a complex containing domain 3 from the PSIV IGR IRES RNA bound to the 70S ribosome.
Descriptor: 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Zhu, J, Korostelev, A, Costantino, D, Noller, H.F, Kieft, J.S.
Deposit date:2010-12-13
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome.
Proc.Natl.Acad.Sci.USA, 108, 2011
4W2G
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Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (soaked), mRNA and three deacylated tRNAs in the A, P and E sites
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
Authors:Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V.
Deposit date:2014-09-12
Release date:2014-10-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol.Cell, 56, 2014
4V8N
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The crystal structure of agmatidine tRNA-Ile2 bound to the 70S ribosome in the A and P site.
Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Voorhees, R.M, Mandal, D, Neubauer, C, Koehrer, C, RajBhandary, U.L, Ramakrishnan, V.
Deposit date:2013-02-13
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Structural Basis for Specific Decoding of Aua by Isoleucine tRNA on the Ribosome
Nat.Struct.Mol.Biol., 20, 2013
4V9A
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Crystal Structure of the 70S ribosome with tetracycline.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Jenner, L, Yusupov, M, Yusupova, G.
Deposit date:2012-07-18
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.2999 Å)
Cite:Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4W2E
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Crystal structure of Elongation Factor 4 (EF4/LepA) bound to the Thermus thermophilus 70S ribosome
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Gagnon, M.G, Lin, J, Steitz, T.A.
Deposit date:2014-06-04
Release date:2014-10-01
Last modified:2023-07-26
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome.
Science, 345, 2014
4V4T
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Crystal structure of the whole ribosomal complex with a stop codon in the A-site.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Petry, S, Brodersen, D.E, Murphy IV, F.V, Dunham, C.M, Selmer, M, Tarry, M.J, Kelley, A.C, Ramakrishnan, V.
Deposit date:2005-10-12
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (6.46 Å)
Cite:Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon.
Cell(Cambridge,Mass.), 123, 2005
4V55
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Crystal structure of the bacterial ribosome from Escherichia coli in complex with gentamicin and ribosome recycling factor (RRF).
Descriptor: (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 16S rRNA, 23S rRNA, ...
Authors:Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D.
Deposit date:2007-06-17
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
Nat.Struct.Mol.Biol., 14, 2007
4V5K
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Structure of cytotoxic domain of colicin E3 bound to the 70S ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Ng, C.L, Lang, K, Meenan, N.A.G, Sharma, A, Kelley, A.C, Kleanthous, C, Ramakrishnan, V.
Deposit date:2010-05-29
Release date:2014-07-09
Last modified:2019-07-31
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis for 16S Ribosomal RNA Cleavage by the Cytotoxic Domain of Colicin E3.
Nat.Struct.Mol.Biol., 17, 2010
4V69
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Ternary complex-bound E.coli 70S ribosome.
Descriptor: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Villa, E, Sengupta, J, Trabuco, L.G, LeBarron, J, Baxter, W.T, Shaikh, T.R, Grassucci, R.A, Nissen, P, Ehrenberg, M, Schulten, K, Frank, J.
Deposit date:2008-12-11
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis
Proc.Natl.Acad.Sci.USA, 106, 2009

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