3QT5
| Crystal structure of Staphylococcus epidermidis mevalonate diphosphate decarboxylase | Descriptor: | Mevalonate diphosphate decarboxylase | Authors: | Barta, M.L, Skaff, A.D, McWhorter, W.J, Miziorko, H.M, Geisbrecht, B.V. | Deposit date: | 2011-02-22 | Release date: | 2011-05-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.848 Å) | Cite: | Crystal structures of Staphylococcus epidermidis mevalonate diphosphate decarboxylase bound to inhibitory analogs reveal new insight into substrate binding and catalysis. J.Biol.Chem., 286, 2011
|
|
6N10
| Crystal structure of Arabidopsis thaliana mevalonate 5-diphosphate decarboxylase 1 complexed with (R)-MVAPP | Descriptor: | (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, Diphosphomevalonate decarboxylase MVD1, peroxisomal, ... | Authors: | Noel, J.P, Thomas, S.T, Louie, G.V. | Deposit date: | 2018-11-07 | Release date: | 2019-07-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Substrate Specificity and Engineering of Mevalonate 5-Phosphate Decarboxylase. Acs Chem.Biol., 14, 2019
|
|
6N0Z
| |
3QT6
| Crystal structure of Staphylococcus epidermidis mevalonate diphosphate decarboxylase complexed with inhibitor DPGP | Descriptor: | 1-({[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}acetyl)-L-proline, Mevalonate diphosphate decarboxylase | Authors: | Barta, M.L, Skaff, A.D, McWhorter, W.J, Miziorko, H.M, Geisbrecht, B.V. | Deposit date: | 2011-02-22 | Release date: | 2011-05-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.047 Å) | Cite: | Crystal structures of Staphylococcus epidermidis mevalonate diphosphate decarboxylase bound to inhibitory analogs reveal new insight into substrate binding and catalysis. J.Biol.Chem., 286, 2011
|
|
3QT8
| Crystal structure of mutant S192A Staphylococcus epidermidis mevalonate diphosphate decarboxylase complexed with inhibitor 6-FMVAPP | Descriptor: | (3R)-3-(fluoromethyl)-3-hydroxy-5-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}pentanoic acid, GLYCEROL, Mevalonate diphosphate decarboxylase | Authors: | Barta, M.L, Skaff, A.D, McWhorter, W.J, Miziorko, H.M, Geisbrecht, B.V. | Deposit date: | 2011-02-22 | Release date: | 2011-05-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of Staphylococcus epidermidis mevalonate diphosphate decarboxylase bound to inhibitory analogs reveal new insight into substrate binding and catalysis. J.Biol.Chem., 286, 2011
|
|
6N0X
| |
3QT7
| Crystal structure of Staphylococcus epidermidis mevalonate diphosphate decarboxylase complexed with inhibitor 6-FMVAPP | Descriptor: | (3R)-3-(fluoromethyl)-3-hydroxy-5-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}pentanoic acid, Mevalonate diphosphate decarboxylase | Authors: | Barta, M.L, Skaff, A.D, McWhorter, W.J, Miziorko, H.M, Geisbrecht, B.V. | Deposit date: | 2011-02-22 | Release date: | 2011-05-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.199 Å) | Cite: | Crystal structures of Staphylococcus epidermidis mevalonate diphosphate decarboxylase bound to inhibitory analogs reveal new insight into substrate binding and catalysis. J.Biol.Chem., 286, 2011
|
|
6N0Y
| |
2OI2
| Streptococcus pneumoniae Mevalonate Kinase in Complex with Diphosphomevalonate | Descriptor: | (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, MAGNESIUM ION, Mevalonate kinase | Authors: | Andreassi, J.L, Bilder, P.W, Vetting, M.W, Roderick, S.L, Leyh, T.S. | Deposit date: | 2007-01-10 | Release date: | 2007-05-01 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the Streptococcus pneumoniae mevalonate kinase in complex with diphosphomevalonate. Protein Sci., 16, 2007
|
|
2R42
| The Biochemical and Structural Basis for feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism | Descriptor: | MAGNESIUM ION, Mevalonate kinase, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE | Authors: | Fu, Z, Voynova, N.E, Miziorko, H.M, Kim, J.P. | Deposit date: | 2007-08-30 | Release date: | 2008-06-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism. Biochemistry, 47, 2008
|
|
2R3V
| |
4DPU
| |
4DPX
| |
4DPT
| Crystal structure of Staphylococcus epidermidis mevalonate diphosphate decarboxylase complexed with inhibitor 6-FMVAPP and ATPgS | Descriptor: | (3R)-3-(fluoromethyl)-3-hydroxy-5-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}pentanoic acid, GLYCEROL, Mevalonate diphosphate decarboxylase, ... | Authors: | Barta, M.L, McWhorter, W.J, Geisbrecht, B.V. | Deposit date: | 2012-02-14 | Release date: | 2012-07-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.191 Å) | Cite: | Structural basis for nucleotide binding and reaction catalysis in mevalonate diphosphate decarboxylase. Biochemistry, 51, 2012
|
|
4DU8
| |
4DXL
| |
4DPW
| Crystal structure of Staphylococcus epidermidis D283A mevalonate diphosphate decarboxylase complexed with mevalonate diphosphate and ATPgS | Descriptor: | (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, FORMIC ACID, GLYCEROL, ... | Authors: | Barta, M.L, McWhorter, W.J, Geisbrecht, B.V. | Deposit date: | 2012-02-14 | Release date: | 2012-07-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.605 Å) | Cite: | Structural basis for nucleotide binding and reaction catalysis in mevalonate diphosphate decarboxylase. Biochemistry, 51, 2012
|
|
4DPY
| |
4DU7
| |
4ED4
| |
4EMD
| |