7W75
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w75 by Molmil](/molmil-images/mine/7w75) | |
7W76
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w76 by Molmil](/molmil-images/mine/7w76) | Crystal structure of the K. lactis Bre1 RBD in complex with Rad6, crystal form II | Descriptor: | E3 ubiquitin-protein ligase BRE1, GLYCEROL, SULFATE ION, ... | Authors: | Shi, M, Zhao, J, Xiang, S. | Deposit date: | 2021-12-03 | Release date: | 2023-03-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural basis for the Rad6 activation by the Bre1 N-terminal domain. Elife, 12, 2023
|
|
7WLH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wlh by Molmil](/molmil-images/mine/7wlh) | |
7V8F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v8f by Molmil](/molmil-images/mine/7v8f) | Crystal structure of UBE2L3 bound to HOIP RING1 domain. | Descriptor: | E3 ubiquitin-protein ligase RNF31, Ubiquitin-conjugating enzyme E2 L3, ZINC ION | Authors: | Liu, J, Wang, Y, Pan, L. | Deposit date: | 2021-08-22 | Release date: | 2022-03-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7UVC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uvc by Molmil](/molmil-images/mine/7uvc) | Rad6(P43L)-Bre1 Complex | Descriptor: | E3 ubiquitin-protein ligase BRE1, Ubiquitin-conjugating enzyme E2 2 | Authors: | Shukla, P.K, Chandrasekharan, M.B. | Deposit date: | 2022-04-29 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structure and functional determinants of Rad6-Bre1 subunits in the histone H2B ubiquitin-conjugating complex. Nucleic Acids Res., 51, 2023
|
|
7UV8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uv8 by Molmil](/molmil-images/mine/7uv8) | Rad6-Bre1 Complex | Descriptor: | E3 ubiquitin-protein ligase BRE1, Ubiquitin-conjugating enzyme E2 2 | Authors: | Shukla, P.K, Chandrasekharan, M.B. | Deposit date: | 2022-04-29 | Release date: | 2023-01-11 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure and functional determinants of Rad6-Bre1 subunits in the histone H2B ubiquitin-conjugating complex. Nucleic Acids Res., 51, 2023
|
|
2YB6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2yb6 by Molmil](/molmil-images/mine/2yb6) | Native human Rad6 | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, UBIQUITIN-CONJUGATING ENZYME E2 B | Authors: | Hibbert, R.G, Sixma, T.K. | Deposit date: | 2011-03-02 | Release date: | 2011-04-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | E3 Ligase Rad18 Promotes Monoubiquitination Rather Than Ubiquitin Chain Formation by E2 Enzyme Rad6. Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
2YBF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ybf by Molmil](/molmil-images/mine/2ybf) | Complex of Rad18 (Rad6 binding domain) with Rad6b | Descriptor: | BETA-MERCAPTOETHANOL, E3 UBIQUITIN-PROTEIN LIGASE RAD18, SODIUM ION, ... | Authors: | Hibbert, R.G, Sixma, T.K. | Deposit date: | 2011-03-08 | Release date: | 2011-04-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | E3 Ligase Rad18 Promotes Monoubiquitination Rather Than Ubiquitin Chain Formation by E2 Enzyme Rad6. Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
4M1N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4m1n by Molmil](/molmil-images/mine/4m1n) | Crystal structure of Plasmodium falciparum ubiquitin conjugating enzyme UBC9 | Descriptor: | SODIUM ION, Ubiquitin conjugating enzyme UBC9 | Authors: | Boucher, L.E, Reiter, K.H, Bosch, J, Matunis, J.M. | Deposit date: | 2013-08-03 | Release date: | 2013-08-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Identification of Biochemically Distinct Properties of the Small Ubiquitin-related Modifier (SUMO) Conjugation Pathway in Plasmodium falciparum. J.Biol.Chem., 288, 2013
|
|
6S98
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s98 by Molmil](/molmil-images/mine/6s98) | |
6S96
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s96 by Molmil](/molmil-images/mine/6s96) | |
2Z5D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2z5d by Molmil](/molmil-images/mine/2z5d) | Human ubiquitin-conjugating enzyme E2 H | Descriptor: | SODIUM ION, Ubiquitin-conjugating enzyme E2 H | Authors: | Bochkarev, A, Cui, H, Walker, J.R, Newman, E.M, Mackenzie, F, Battaile, K.P, Sundstrom, M, Arrowsmith, C, Edwards, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2007-07-06 | Release date: | 2007-10-09 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. MOL.CELL PROTEOMICS, 11, 2012
|
|
6SYF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6syf by Molmil](/molmil-images/mine/6syf) | Human Ubc9 with covalent isopeptide ligand | Descriptor: | ACE-ILE-LYS-GLN-GLU, ACE-LEU-ARG-LEU-ARG-GLY-CYS, SUMO-conjugating enzyme UBC9 | Authors: | Hofmann, R, Akimoto, G, Wucherpfennig, T.G, Zeymer, C, Bode, J.W. | Deposit date: | 2019-09-27 | Release date: | 2020-08-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Lysine acylation using conjugating enzymes for site-specific modification and ubiquitination of recombinant proteins. Nat.Chem., 12, 2020
|
|
4JUE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4jue by Molmil](/molmil-images/mine/4jue) | |
6R75
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6r75 by Molmil](/molmil-images/mine/6r75) | Crystal structure of human Ube2T E54R mutant | Descriptor: | Ubiquitin-conjugating enzyme E2 T | Authors: | Chaugule, V.K, Rennie, M.L, Walden, H, Arkinson, C, Kamarainen, O, Toth, R. | Deposit date: | 2019-03-28 | Release date: | 2019-10-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Allosteric mechanism for site-specific ubiquitination of FANCD2. Nat.Chem.Biol., 16, 2020
|
|
3BZH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bzh by Molmil](/molmil-images/mine/3bzh) | Crystal structure of human ubiquitin-conjugating enzyme E2 E1 | Descriptor: | GLYCEROL, Ubiquitin-conjugating enzyme E2 E1 | Authors: | Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2008-01-18 | Release date: | 2008-02-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics, 11, 2012
|
|
4NR3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nr3 by Molmil](/molmil-images/mine/4nr3) | |
4NRI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nri by Molmil](/molmil-images/mine/4nri) | |
4NRG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nrg by Molmil](/molmil-images/mine/4nrg) | |
5A4P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5a4p by Molmil](/molmil-images/mine/5a4p) | Structure of UBE2Z provides functional insight into specificity in the FAT10 conjugation machinery | Descriptor: | DI(HYDROXYETHYL)ETHER, MALONATE ION, UBIQUITIN-CONJUGATING ENZYME E2 Z | Authors: | Schelpe, J, Monte, D, Dewitte, F, Sixma, T.K, Rucktooa, P. | Deposit date: | 2015-06-11 | Release date: | 2015-11-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of Ube2Z Provides Functional Insight Into Specificity in the Fat10 Conjugation Machinery J.Biol.Chem., 291, 2016
|
|
4DS2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ds2 by Molmil](/molmil-images/mine/4ds2) | |
4ONL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4onl by Molmil](/molmil-images/mine/4onl) | Crystal structure of human Mms2/Ubc13_D81N, R85S, A122V, N123P | Descriptor: | Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 | Authors: | Hodge, C.D, Edwards, R.A, Glover, J.N.M. | Deposit date: | 2014-01-28 | Release date: | 2015-05-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting. Acs Chem.Biol., 10, 2015
|
|
7YW1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7yw1 by Molmil](/molmil-images/mine/7yw1) | crystal structure of UBE2O | Descriptor: | (E3-independent) E2 ubiquitin-conjugating enzyme UBE2O | Authors: | Fu, Z, Zhu, W, Huang, H. | Deposit date: | 2022-08-20 | Release date: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.27 Å) | Cite: | crystal structure of UBE2O To Be Published
|
|
2GJD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gjd by Molmil](/molmil-images/mine/2gjd) | Distinct functional domains of Ubc9 dictate cell survival and resistance to genotoxic stress | Descriptor: | Ubiquitin-conjugating enzyme E2-18 kDa | Authors: | van Waardenburg, R.C, Duda, D.M, Lancaster, C.S, Schulman, B.A, Bjornsti, M.A. | Deposit date: | 2006-03-30 | Release date: | 2006-07-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Distinct functional domains of ubc9 dictate cell survival and resistance to genotoxic stress. Mol.Cell.Biol., 26, 2006
|
|
2KLY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kly by Molmil](/molmil-images/mine/2kly) | |