5DUQ
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![BU of 5duq by Molmil](/molmil-images/mine/5duq) | Active human c1-inhibitor in complex with dextran sulfate | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Plasma protease C1 inhibitor, SULFITE ION, ... | Authors: | Dijk, M, Holkers, J, Voskamp, P, Giannetti, B.M, Waterreus, W.J, van Veen, H.A, Pannu, N.S. | Deposit date: | 2015-09-20 | Release date: | 2016-08-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | How Dextran Sulfate Affects C1-inhibitor Activity: A Model for Polysaccharide Potentiation. Structure, 24, 2016
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3T1P
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8GXV
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4P0O
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![BU of 4p0o by Molmil](/molmil-images/mine/4p0o) | Cleaved Serpin 42Da | Descriptor: | Serine protease inhibitor 4, isoform B | Authors: | Ellisdon, A.M, Whisstock, J.C. | Deposit date: | 2014-02-21 | Release date: | 2014-05-07 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | High resolution structure of cleaved Serpin 42 Da from Drosophila melanogaster. Bmc Struct.Biol., 14, 2014
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4P0F
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![BU of 4p0f by Molmil](/molmil-images/mine/4p0f) | Cleaved Serpin 42Da (C 2 2 21) | Descriptor: | Serine protease inhibitor 4, isoform B | Authors: | Ellisdon, A.M, Whisstock, J.C. | Deposit date: | 2014-02-21 | Release date: | 2014-05-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | High resolution structure of cleaved Serpin 42 Da from Drosophila melanogaster. Bmc Struct.Biol., 14, 2014
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5INW
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![BU of 5inw by Molmil](/molmil-images/mine/5inw) | Structure of reaction loop cleaved lamprey angiotensinogen | Descriptor: | C-terminal peptide of Putative angiotensinogen, Putative angiotensinogen, SULFATE ION | Authors: | Wei, H, Zhou, A. | Deposit date: | 2016-03-08 | Release date: | 2016-10-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Heparin Binds Lamprey Angiotensinogen and Promotes Thrombin Inhibition through a Template Mechanism J.Biol.Chem., 291, 2016
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5M3X
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3STO
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![BU of 3sto by Molmil](/molmil-images/mine/3sto) | Serpin from the trematode Schistosoma Haematobium | Descriptor: | Serine protease inhibitor | Authors: | Granzin, J, Weiergraeber, O.H, Lee, X, Blanton, R.E. | Deposit date: | 2011-07-11 | Release date: | 2012-05-30 | Last modified: | 2013-01-23 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Three-dimensional structure of a schistosome serpin revealing an unusual configuration of the helical subdomain. Acta Crystallogr.,Sect.D, 68, 2012
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5IO1
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8H4X
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![BU of 8h4x by Molmil](/molmil-images/mine/8h4x) | Structure of cleaved Serpin B9 | Descriptor: | 1,2-ETHANEDIOL, Serpin B9, ZINC ION | Authors: | Zhou, A, Yan, T. | Deposit date: | 2022-10-11 | Release date: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Expression, purification and crystallization of cleaved Serpin B9 To Be Published
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5EI0
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![BU of 5ei0 by Molmil](/molmil-images/mine/5ei0) | Structure of RCL-cleaved vaspin (serpinA12) | Descriptor: | Serpin A12 | Authors: | Pippel, J, Kuettner, B.E, Ulbricht, D, Daberger, J, Schultz, S, Heiker, J.T, Strater, N. | Deposit date: | 2015-10-29 | Release date: | 2015-11-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of cleaved vaspin (serpinA12). Biol.Chem., 397, 2016
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8PI2
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5M3Y
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![BU of 5m3y by Molmil](/molmil-images/mine/5m3y) | Crystal structure of human glycosylated angiotensinogen | Descriptor: | Angiotensinogen, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Yan, Y, Read, R.J. | Deposit date: | 2016-10-17 | Release date: | 2017-12-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for the specificity of renin-mediated angiotensinogen cleavage. J. Biol. Chem., 294, 2019
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3UT3
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![BU of 3ut3 by Molmil](/molmil-images/mine/3ut3) | A novel PAI-I inhibitor and its structural mechanism | Descriptor: | 2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione, Plasminogen activator inhibitor 1 | Authors: | Lin, Z.H, Hong, Z.B, Shi, X.L, Hu, L.H, Andreasen, P.A, Huang, M.D. | Deposit date: | 2011-11-25 | Release date: | 2013-02-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | A novel PAI-I inhibitor and its structural mechanism To be Published
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8H55
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![BU of 8h55 by Molmil](/molmil-images/mine/8h55) | The structure of zebrafish angiotensinogen | Descriptor: | Angiotensinogen, SULFATE ION | Authors: | Zhou, A, Wei, H. | Deposit date: | 2022-10-12 | Release date: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | BIOLOGICAL IMPLICATIONS OF A 2 ANGSTROMS STRUCTURE OF DIMERIC ANGIOTENSINOGEN To Be Published
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5NBV
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8P4U
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![BU of 8p4u by Molmil](/molmil-images/mine/8p4u) | Alpha-1-antitrypsin - Sydney variant (G192C) | Descriptor: | Alpha-1-antitrypsin | Authors: | Kamuda, K, Lomas, D.A, Irving, J.A. | Deposit date: | 2023-05-23 | Release date: | 2024-04-03 | Last modified: | 2024-07-17 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A novel pathological mutant reveals the role of torsional flexibility in the serpin breach in adoption of an aggregation-prone intermediate. Febs J., 291, 2024
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8P4J
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![BU of 8p4j by Molmil](/molmil-images/mine/8p4j) | Alpha-1-antitrypsin - Sydney variant (G192C) | Descriptor: | Alpha-1-antitrypsin | Authors: | Kamuda, K, Lomas, D.A, Irving, J.A. | Deposit date: | 2023-05-22 | Release date: | 2024-04-03 | Last modified: | 2024-07-17 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | A novel pathological mutant reveals the role of torsional flexibility in the serpin breach in adoption of an aggregation-prone intermediate. Febs J., 291, 2024
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4PYW
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![BU of 4pyw by Molmil](/molmil-images/mine/4pyw) | 1.92 angstrom crystal structure of A1AT:TTAI ternary complex | Descriptor: | ACE-THR-THR-ALA-ILE-NH2, Alpha-1-antitrypsin, GLYCEROL | Authors: | Nyon, M.P, Day, J, Gooptu, B. | Deposit date: | 2014-03-28 | Release date: | 2015-06-10 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | An integrative approach combining ion mobility mass spectrometry, X-ray crystallography, and nuclear magnetic resonance spectroscopy to study the conformational dynamics of alpha 1 -antitrypsin upon ligand binding. Protein Sci., 24, 2015
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7BFI
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6CJ7
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![BU of 6cj7 by Molmil](/molmil-images/mine/6cj7) | Crystal structure of Manduca sexta Serine protease inhibitor (Serpin)-12 | Descriptor: | Serpin-12 | Authors: | Gulati, M, Hu, Y, Peng, S, Pathak, P.K, Wang, Y, Deng, J, Jiang, H. | Deposit date: | 2018-02-26 | Release date: | 2018-07-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Manduca sexta serpin-12 controls the prophenoloxidase activation system in larval hemolymph. Insect Biochem. Mol. Biol., 99, 2018
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4ZK0
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![BU of 4zk0 by Molmil](/molmil-images/mine/4zk0) | Psoriasis pathogenesis - Pso p27 constitute a compact structure forming large aggregates. High pH structure | Descriptor: | Serpin B4, ZINC ION | Authors: | Helland, R, Lysvand, H, Slupphaug, G, Iversen, O.J. | Deposit date: | 2015-04-29 | Release date: | 2015-07-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Psoriasis pathogenesis - Pso p27 constitutes a compact structure forming large aggregates. Biochem Biophys Rep, 2, 2015
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4RSQ
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![BU of 4rsq by Molmil](/molmil-images/mine/4rsq) | 2.9A resolution structure of SRPN2 (K198C/E359C) from Anopheles gambiae | Descriptor: | Serpin 2 | Authors: | Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. | Deposit date: | 2014-11-10 | Release date: | 2014-12-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae. J.Biol.Chem., 290, 2015
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4ROA
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![BU of 4roa by Molmil](/molmil-images/mine/4roa) | 1.90A resolution structure of SRPN2 (S358W) from Anopheles gambiae | Descriptor: | Serpin 2 | Authors: | Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. | Deposit date: | 2014-10-28 | Release date: | 2014-12-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae. J.Biol.Chem., 290, 2015
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4ZK3
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