7BFI

A double-histidine mutant of HSP47 slows down client release at low pH

Summary for 7BFI

• Entry DOI: 10.2210/pdb7bfi/pdb
• Related: 3ZHA 4AU2 4AU3 4AU4
• Descriptor: Collagen-binding protein, 15R8 collagen model peptide (3 entities in total)
• Functional Keywords: hsp47, collagen-binding, ph-mediated client release, chaperone
• Biological source: Canis lupus familiaris (Dog); More
• Total number of polymer chains: 10
• Total formula weight: 185610.37

Authors

Oecal, S.,Baumann, U. (deposition date: 2021-01-03, release date: 2021-11-10, Last modification date: 2024-01-31)

• Primary citation: Abraham, E.T.,Oecal, S.,Morgelin, M.,Schmid, P.W.N.,Buchner, J.,Baumann, U.,Gebauer, J.M.; Collagen's primary structure determines collagen:HSP47 complex stoichiometry.; J.Biol.Chem., 297:101169-101169, 2021; PubMed: 34487762; DOI: 10.1016/j.jbc.2021.101169

Experimental method

X-RAY DIFFRACTION (2.44 Å)