1HNW
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![BU of 1hnw by Molmil](/molmil-images/mine/1hnw) | STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH TETRACYCLINE | Descriptor: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Brodersen, D.E, Clemons Jr, W.M, Carter, A.P, Morgan-Warren, R, Wimberly, B.T, Ramakrishnan, V. | Deposit date: | 2000-12-08 | Release date: | 2001-02-21 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit. Cell(Cambridge,Mass.), 103, 2000
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6CAQ
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5WNU
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![BU of 5wnu by Molmil](/molmil-images/mine/5wnu) | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | Descriptor: | (1R,2S,3S,4R,6R)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-alpha-L-altropyranosyl)-beta-L-arabinofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-allopyranoside, 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, ... | Authors: | DeMirci, H. | Deposit date: | 2017-08-01 | Release date: | 2018-02-21 | Last modified: | 2020-10-21 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation. Nat. Struct. Mol. Biol., 25, 2018
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5BR8
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![BU of 5br8 by Molmil](/molmil-images/mine/5br8) | Ambient-temperature crystal structure of 30S ribosomal subunit from Thermus thermophilus in complex with paromomycin | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Sierra, R.G, Gati, C, Laksmono, H, Dao, E.H, Gul, S, Fuller, F, Kern, J, Chatterjee, R, Ibrahim, M, Brewster, A, Young, I.D, Michels-Clark, T, Aquila, A, Mengning, L, Hunter, M.S, Koglin, J.E, Boutet, S, Junco, E.A, Hayes, B, Bogan, M.J, Hampton, C.Y, Puglisi, E.V, Sauter, N.K, Stan, C.A, Zouni, A, Yano, J, Yachandra, V.K, Soltis, S.M, Puglisi, J.D, DeMirci, H. | Deposit date: | 2015-05-29 | Release date: | 2015-11-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Ambient-temperature crystal structure of 30S ribosomal subunit from Thermus thermophilus in complex with paromomycin To Be Published
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1HNX
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![BU of 1hnx by Molmil](/molmil-images/mine/1hnx) | STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH PACTAMYCIN | Descriptor: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Brodersen, D.E, Clemons Jr, W.M, Carter, A.P, Morgan-Warren, R, Wimberly, B.T, Ramakrishnan, V. | Deposit date: | 2000-12-08 | Release date: | 2001-02-21 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit. Cell(Cambridge,Mass.), 103, 2000
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4K0K
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![BU of 4k0k by Molmil](/molmil-images/mine/4k0k) | Crystal structure of the Thermus thermophilus 30S ribosomal subunit complexed with a serine-ASL and mRNA containing a stop codon | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Fernandez, I.S, Ng, C.L, Kelley, A.C, Guowei, W, Yu, Y.T, Ramakrishnan, V. | Deposit date: | 2013-04-04 | Release date: | 2013-06-26 | Last modified: | 2013-08-21 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Unusual base pairing during the decoding of a stop codon by the ribosome. Nature, 500, 2013
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4YHH
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![BU of 4yhh by Molmil](/molmil-images/mine/4yhh) | Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with tigecycline | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Schedlbauer, A, Kaminishi, T, Ochoa-Lizarralde, B, Dhimole, N, Zhou, S, Lopez-Alonso, J.P, Connell, S.R, Fucini, P. | Deposit date: | 2015-02-27 | Release date: | 2015-04-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.417 Å) | Cite: | Structural characterization of an alternative mode of tigecycline binding to the bacterial ribosome. Antimicrob.Agents Chemother., 59, 2015
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4X66
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![BU of 4x66 by Molmil](/molmil-images/mine/4x66) | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Demirci, H, Chen, J, Choi, J, Soltis, M, Puglisi, J.D. | Deposit date: | 2014-12-06 | Release date: | 2015-11-18 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (3.446 Å) | Cite: | N(6)-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics. Nat.Struct.Mol.Biol., 23, 2016
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4X62
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![BU of 4x62 by Molmil](/molmil-images/mine/4x62) | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Demirci, H, Chen, J, Choi, J, Soltis, M, Puglisi, J.D. | Deposit date: | 2014-12-06 | Release date: | 2015-11-18 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (3.4492 Å) | Cite: | N(6)-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics. Nat.Struct.Mol.Biol., 23, 2016
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4V5E
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![BU of 4v5e by Molmil](/molmil-images/mine/4v5e) | Insights into translational termination from the structure of RF2 bound to the ribosome | Descriptor: | 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | Authors: | Weixlbaumer, A, Jin, H, Neubauer, C, Voorhees, R.M, Petry, S, Kelley, A.C, Ramakrishnan, V. | Deposit date: | 2009-04-30 | Release date: | 2014-07-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | Insights Into Translational Termination from the Structure of Rf2 Bound to the Ribosome. Science, 322, 2008
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6CAO
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![BU of 6cao by Molmil](/molmil-images/mine/6cao) | |
4DR5
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![BU of 4dr5 by Molmil](/molmil-images/mine/4dr5) | Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with codon, crystallographically disordered cognate transfer RNA anticodon stem-loop and streptomycin bound | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. | Deposit date: | 2012-02-16 | Release date: | 2012-11-14 | Last modified: | 2013-01-30 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | A structural basis for streptomycin-induced misreading of the genetic code. Nat Commun, 4, 2013
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6MKN
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![BU of 6mkn by Molmil](/molmil-images/mine/6mkn) | Structure of the Thermus thermophilus 30S ribosomal subunit complexed with an inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 2 (TRNAARG2) bound to an mRNA with an CGU-codon in the A-site and paromomycin | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Cantara, W.A, DeMirci, H, Agris, P.F. | Deposit date: | 2018-09-25 | Release date: | 2019-04-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.46 Å) | Cite: | A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. J.Mol.Biol., 432, 2020
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4JI0
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![BU of 4ji0 by Molmil](/molmil-images/mine/4ji0) | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | Descriptor: | 16S rRNA, MAGNESIUM ION, ZINC ION, ... | Authors: | Demirci, H, Wang, L, Murphy IV, F, Murphy, E, Carr, J, Blanchard, S, Jogl, G, Dahlberg, A.E, Gregory, S.T. | Deposit date: | 2013-03-05 | Release date: | 2013-11-06 | Last modified: | 2013-12-04 | Method: | X-RAY DIFFRACTION (3.492 Å) | Cite: | The central role of protein S12 in organizing the structure of the decoding site of the ribosome. Rna, 19, 2013
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6OXI
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![BU of 6oxi by Molmil](/molmil-images/mine/6oxi) | Dimeric E.coli YoeB bound to Thermus thermophilus 70S post-cleavage (UAA) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Pavelich, I.J, Hoffer, E.D, Maehigashi, T, Dunham, C.M. | Deposit date: | 2019-05-13 | Release date: | 2019-08-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.495 Å) | Cite: | Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability. Nucleic Acids Res., 47, 2019
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5WNS
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![BU of 5wns by Molmil](/molmil-images/mine/5wns) | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | Descriptor: | 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | DeMirci, H. | Deposit date: | 2017-08-01 | Release date: | 2018-02-21 | Last modified: | 2020-10-21 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation. Nat. Struct. Mol. Biol., 25, 2018
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5WNQ
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![BU of 5wnq by Molmil](/molmil-images/mine/5wnq) | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | Descriptor: | 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | DeMirci, H. | Deposit date: | 2017-08-01 | Release date: | 2018-02-21 | Last modified: | 2020-10-21 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation. Nat. Struct. Mol. Biol., 25, 2018
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4TUE
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![BU of 4tue by Molmil](/molmil-images/mine/4tue) | |
6QNQ
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![BU of 6qnq by Molmil](/molmil-images/mine/6qnq) | 70S ribosome initiation complex (IC) with experimentally assigned potassium ions | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rozov, A, Khusainov, I, Yusupov, M, Yusupova, G. | Deposit date: | 2019-02-11 | Release date: | 2019-06-19 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Importance of potassium ions for ribosome structure and function revealed by long-wavelength X-ray diffraction. Nat Commun, 10, 2019
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5WNR
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![BU of 5wnr by Molmil](/molmil-images/mine/5wnr) | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | Descriptor: | 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | DeMirci, H. | Deposit date: | 2017-08-01 | Release date: | 2018-02-21 | Last modified: | 2020-10-21 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation. Nat. Struct. Mol. Biol., 25, 2018
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4V6G
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![BU of 4v6g by Molmil](/molmil-images/mine/4v6g) | Initiation complex of 70S ribosome with two tRNAs and mRNA. | Descriptor: | 16S RRNA (E.COLI NUMBERING), 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | Authors: | Jenner, L.B, Yusupova, G, Yusupov, M. | Deposit date: | 2009-07-10 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural aspects of messenger RNA reading frame maintenance by the ribosome. Nat.Struct.Mol.Biol., 17, 2010
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5IWA
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![BU of 5iwa by Molmil](/molmil-images/mine/5iwa) | Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with the GE81112 peptide antibiotic | Descriptor: | (2S,3S)-2-{[(2S)-3-(2-amino-1H-imidazol-5-yl)-2-{[(2S,4S)-5-(carbamoyloxy)-4-hydroxy-2-({[(2S,3S)-3-hydroxypiperidin-2-yl]carbonyl}amino)pentanoyl]amino}propanoyl]amino}-3-(2-chloro-1H-imidazol-5-yl)-3-hydroxypropanoic acid, 16S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Schedlbauer, A, Kaminishi, T, Ochoa-Lizarralde, B, Chieko, N, Masahito, K, Takemoto, C, Yokoyama, S, Connell, S.R, Fucini, P. | Deposit date: | 2016-03-22 | Release date: | 2016-04-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding. Proc.Natl.Acad.Sci.USA, 113, 2016
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6BUW
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![BU of 6buw by Molmil](/molmil-images/mine/6buw) | Thermus thermophilus 70S complex containing 16S G299A ram mutation and empty A site. | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M. | Deposit date: | 2017-12-11 | Release date: | 2018-11-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding. Nucleic Acids Res., 47, 2019
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6UCQ
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![BU of 6ucq by Molmil](/molmil-images/mine/6ucq) | Crystal structure of the Thermus thermophilus 70S ribosome recycling complex | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Zhou, D, Tanzawa, T, Gagnon, M.G, Lin, J. | Deposit date: | 2019-09-17 | Release date: | 2019-12-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural basis for ribosome recycling by RRF and tRNA. Nat.Struct.Mol.Biol., 27, 2020
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6CAS
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![BU of 6cas by Molmil](/molmil-images/mine/6cas) | |