8SOJ
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7Y5Q
| Structure of 1:1 PAPP-A.STC2 complex(half map) | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,Pappalysin-1, Stanniocalcin-2, ZINC ION | Authors: | Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J. | Deposit date: | 2022-06-17 | Release date: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2. Cell Discov, 8, 2022
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7Z7H
| Structure of P. luminescens TccC3-F-actin complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5-DIPHOSPHORIBOSE, Actin, ... | Authors: | Belyy, A, Raunser, S. | Deposit date: | 2022-03-15 | Release date: | 2022-06-29 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin. Nat Commun, 13, 2022
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6DBU
| Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | Descriptor: | CALCIUM ION, Forward strand RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... | Authors: | Wu, H, Liao, M, Ru, H, Mi, W. | Deposit date: | 2018-05-03 | Release date: | 2018-08-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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8FNE
| phiPA3 PhuN Tetramer, p2 | Descriptor: | Maltose/maltodextrin-binding periplasmic protein, PhuN | Authors: | Nieweglowska, E.S, Brilot, A.F, Mendez-Moran, M, Kokontis, C, Baek, M, Li, J, Cheng, Y, Baker, D, Bondy-Denomy, J, Agard, D.A. | Deposit date: | 2022-12-27 | Release date: | 2023-03-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | The phi PA3 phage nucleus is enclosed by a self-assembling 2D crystalline lattice. Nat Commun, 14, 2023
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7P1H
| Structure of the V. vulnificus ExoY-G-actin-profilin complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Belyy, A, Merino, F, Raunser, S. | Deposit date: | 2021-07-01 | Release date: | 2021-11-17 | Last modified: | 2021-12-01 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Mechanism of actin-dependent activation of nucleotidyl cyclase toxins from bacterial human pathogens. Nat Commun, 12, 2021
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7JHH
| Cryo-EM structure of ATP-bound fully inactive AMPK in complex with Fab and nanobody | Descriptor: | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ... | Authors: | Yan, Y, Murkherjee, S, Zhou, X.E, Xu, T.H, Xu, H.E, Kossiakoff, A.A, Melcher, K. | Deposit date: | 2020-07-20 | Release date: | 2021-07-21 | Last modified: | 2021-12-15 | Method: | ELECTRON MICROSCOPY (3.92 Å) | Cite: | Structure of an AMPK complex in an inactive, ATP-bound state. Science, 373, 2021
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6BUZ
| Cryo-EM structure of CENP-A nucleosome in complex with kinetochore protein CENP-N | Descriptor: | DNA (147-MER), Histone H2A, Histone H2B, ... | Authors: | Chittori, S, Hong, J, Kelly, A.E, Bai, Y, Subramaniam, S. | Deposit date: | 2017-12-11 | Release date: | 2017-12-20 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.92 Å) | Cite: | Structural mechanisms of centromeric nucleosome recognition by the kinetochore protein CENP-N. Science, 359, 2018
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7M74
| ATP-bound AMP-activated protein kinase | Descriptor: | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ... | Authors: | Yan, Y, Mukherjee, S, Harikumar, K.G, Strutzenberg, T, Zhou, X.E, Powell, S.K, Xu, T, Sheldon, R, Lamp, J, Brunzelle, J.S, Radziwon, K, Ellis, A, Novick, S.J, Vega, I.E, Jones, R, Miller, L.J, Xu, H.E, Griffin, P.R, Kossiakoff, A.A, Melcher, K. | Deposit date: | 2021-03-26 | Release date: | 2021-12-15 | Last modified: | 2021-12-22 | Method: | ELECTRON MICROSCOPY (3.93 Å) | Cite: | Structure of an AMPK complex in an inactive, ATP-bound state. Science, 373, 2021
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7NZM
| Cryo-EM structure of pre-dephosphorylation complex of phosphorylated eIF2alpha with trapped holophosphatase (PP1A_D64A/PPP1R15A/G-actin/DNase I) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Yan, Y, Hardwick, S, Ron, D. | Deposit date: | 2021-03-24 | Release date: | 2021-09-29 | Last modified: | 2021-10-20 | Method: | ELECTRON MICROSCOPY (3.96 Å) | Cite: | Higher-order phosphatase-substrate contacts terminate the integrated stress response. Nat.Struct.Mol.Biol., 28, 2021
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6DBR
| Cryo-EM structure of RAG in complex with one melted RSS and one unmelted RSS | Descriptor: | CALCIUM ION, Forward strand of melted RSS substrate DNA, Forward strand of unmelted RSS substrate DNA, ... | Authors: | Wu, H, Liao, M, Ru, H, Mi, W. | Deposit date: | 2018-05-03 | Release date: | 2018-08-01 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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6P6W
| Cryo-EM structure of voltage-gated sodium channel NavAb N49K/L109A/M116V/G94C/Q150C disulfide crosslinked mutant in the resting state | Descriptor: | Fusion of Maltose-binding protein and voltage-gated sodium channel NavAb | Authors: | Wisedchaisri, G, Tonggu, L, McCord, E, Gamal El-Din, T.M, Wang, L, Zheng, N, Catterall, W.A. | Deposit date: | 2019-06-04 | Release date: | 2019-08-14 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel. Cell, 178, 2019
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7VGQ
| Cryo-EM structure of Machupo virus polymerase L in complex with matrix protein Z | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,RING finger protein Z, RNA-directed RNA polymerase L, ZINC ION | Authors: | Zhang, X, Ma, J, Zhang, S. | Deposit date: | 2021-09-18 | Release date: | 2021-09-29 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure of Machupo virus polymerase in complex with matrix protein Z. Nat Commun, 12, 2021
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8SOK
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8HGH
| Structure of 2:2 PAPP-A.STC2 complex | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,Pappalysin-1, Stanniocalcin-2, ZINC ION | Authors: | Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J. | Deposit date: | 2022-11-14 | Release date: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (4.16 Å) | Cite: | Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2. Cell Discov, 8, 2022
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7TT4
| BamABCDE bound to substrate EspP class 6 | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,Serine protease EspP chimera, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | Authors: | Doyle, M.T, Jimah, J.R, Dowdy, T, Ohlemacher, S.I, Larion, M, Hinshaw, J.E, Bernstein, H.D. | Deposit date: | 2022-01-31 | Release date: | 2022-03-30 | Last modified: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding. Cell, 185, 2022
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7TT2
| BamABCDE bound to substrate EspP class 3 | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,Serine protease EspP chimera, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | Authors: | Doyle, M.T, Jimah, J.R, Dowdy, T, Ohlemacher, S.I, Larion, M, Hinshaw, J.E, Bernstein, H.D. | Deposit date: | 2022-01-31 | Release date: | 2022-03-30 | Last modified: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding. Cell, 185, 2022
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6DBX
| Cryo-EM structure of RAG in complex with 12-RSS substrate DNA | Descriptor: | CALCIUM ION, Forward strand of 12-RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... | Authors: | Wu, H, Liao, M, Ru, H, Mi, W. | Deposit date: | 2018-05-03 | Release date: | 2018-08-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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7VH1
| Cryo-EM structure of Machupo virus dimeric L-Z complex | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,RING finger protein Z, RNA-directed RNA polymerase L, ZINC ION | Authors: | Zhang, X, Ma, J, Zhang, S. | Deposit date: | 2021-09-20 | Release date: | 2021-09-29 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structure of Machupo virus polymerase in complex with matrix protein Z. Nat Commun, 12, 2021
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8CR9
| Cryo-EM structure of PcrV/Fab(30-B8) | Descriptor: | Heavy chain, Maltose/maltodextrin-binding periplasmic protein,Type III secretion protein PcrV, light chain | Authors: | Yuan, B, Simonis, A, Marlovits, T.C. | Deposit date: | 2023-03-08 | Release date: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa. Cell, 186, 2023
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8SQA
| The cryo-EM structure of the EcBAM/EspP(beta8-12) complex | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,Autotransporter protein EspP translocator, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | Authors: | Wu, R, Noinaj, N. | Deposit date: | 2023-05-04 | Release date: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | BAM orchestrates OMP biogenesis using a beta-templating mechanism To Be Published
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7BXT
| The cryo-EM structure of CENP-A nucleosome in complex with CENP-C peptide and CENP-N N-terminal domain | Descriptor: | CENP-C, DNA (145-mer), Histone H2A type 1-B/E, ... | Authors: | Ariyoshi, M, Makino, F, Fukagawa, T. | Deposit date: | 2020-04-20 | Release date: | 2021-02-10 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-EM structure of the CENP-A nucleosome in complex with phosphorylated CENP-C. Embo J., 40, 2021
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8FV5
| Representation of 16-mer phiPA3 PhuN Lattice, p2 | Descriptor: | Maltose/maltodextrin-binding periplasmic protein, phiPA3 PhuN | Authors: | Nieweglowska, E.S, Brilot, A.F, Mendez-Moran, M, Kokontis, C, Baek, M, Li, J, Cheng, Y, Baker, D, Bondy-Denomy, J, Agard, D.A. | Deposit date: | 2023-01-18 | Release date: | 2023-03-01 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4.21 Å) | Cite: | The phi PA3 phage nucleus is enclosed by a self-assembling 2D crystalline lattice. Nat Commun, 14, 2023
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6DBQ
| Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | Descriptor: | CALCIUM ION, Molecule name: Forward strand of 12-RSS substrate DNA, Molecule name: Forward strand of 23-RSS substrate DNA, ... | Authors: | Wu, H, Liao, M, Ru, H, Mi, W. | Deposit date: | 2018-05-03 | Release date: | 2018-08-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.22 Å) | Cite: | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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3J9P
| Structure of the TRPA1 ion channel determined by electron cryo-microscopy | Descriptor: | Maltose-binding periplasmic protein, Transient receptor potential cation channel subfamily A member 1 chimera | Authors: | Paulsen, C.E, Armache, J.-P, Gao, Y, Cheng, Y, Julius, D. | Deposit date: | 2015-02-14 | Release date: | 2015-04-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.24 Å) | Cite: | Structure of the TRPA1 ion channel suggests regulatory mechanisms. Nature, 520, 2015
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