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PDB: 219 results

8CZE
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BU of 8cze by Molmil
Structure of a Xenopus Nucleosome with Widom 601 DNA
Descriptor: Histone H2A, Histone H2B, Histone H3, ...
Authors:Gu, Y, Ur, S.N, Milano, C.R, Tromer, E.C, Vale-Silva, L.A, Hochwagen, A, Corbett, K.D.
Deposit date:2022-05-24
Release date:2023-06-07
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Chromatin binding by HORMAD proteins regulates meiotic recombination initiation.
Embo J., 43, 2024
4J8V
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BU of 4j8v by Molmil
X-ray structure of NCP145 with bound chlorido(eta-6-p-cymene)(N-phenyl-2-pyridinecarbothioamide)ruthenium(II)
Descriptor: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Adhireksan, Z, Davey, C.A.
Deposit date:2013-02-15
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Novel metal(II) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents
CHEM SCI, 4, 2013
4WU9
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BU of 4wu9 by Molmil
Structure of cisPtNAP-NCP145
Descriptor: DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Chua, E.Y.D, Davey, G.E, Chin, C.F, Droge, P, Ang, W.H, Davey, C.A.
Deposit date:2014-10-31
Release date:2015-09-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Stereochemical control of nucleosome targeting by platinum-intercalator antitumor agents.
Nucleic Acids Res., 43, 2015
1KX4
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BU of 1kx4 by Molmil
X-Ray Structure of the Nucleosome Core Particle, NCP146b, at 2.6 A Resolution
Descriptor: CHLORIDE ION, DNA (5'(ATCTCCAAATATCCCTTGCGGATCGTAGAAAAAGTGTGTCAAACTGCGCTATCAAAGGGAAACTTCAACTGAATTCAGTTGAAGTTTCCCTTTGATAGCGCAGTTTGACACACTTTTTCTACGATCCGCAAGGGATATTTGGAGAT)3'), MANGANESE (II) ION, ...
Authors:Davey, C.A, Sargent, D.F, Luger, K, Maeder, A.W, Richmond, T.J.
Deposit date:2002-01-31
Release date:2002-12-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Solvent Mediated Interactions in the Structure of the Nucleosome Core Particle at 1.9 A Resolution
J.Mol.Biol., 319, 2002
7SWY
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BU of 7swy by Molmil
2.6 A structure of a 40-601[TA-rich+1]-40 nucleosome
Descriptor: DNA Guide Strand, DNA Tracking Strand, Histone H2A, ...
Authors:Nodelman, I.M, Bowman, G.D, Armache, J.-P.
Deposit date:2021-11-21
Release date:2022-03-02
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Nucleosome recognition and DNA distortion by the Chd1 remodeler in a nucleotide-free state.
Nat.Struct.Mol.Biol., 29, 2022
3REK
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BU of 3rek by Molmil
2.6 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp Alpha-Satellite DNA (NCP146b) Derivatized with Oxaliplatin
Descriptor: DNA (146-MER), Histone H2A type1, Histone H2B 1.1, ...
Authors:Wu, B, Davey, C.A.
Deposit date:2011-04-04
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation.
Nucleic Acids Res., 39, 2011
5CP6
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BU of 5cp6 by Molmil
Nucleosome Core Particle with Adducts from the Anticancer Compound, [(eta6-5,8,9,10-tetrahydroanthracene)Ru(ethylenediamine)Cl][PF6]
Descriptor: (ethane6-5,8,9,10-tetrahydroanthracene)Ru(II)(ethylene-diamine)Cl, DNA (145-MER), Histone H2A, ...
Authors:Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
Deposit date:2015-07-21
Release date:2016-06-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:An Organometallic Compound which Exhibits a DNA Topology-Dependent One-Stranded Intercalation Mode.
Angew.Chem.Int.Ed.Engl., 55, 2016
5F99
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BU of 5f99 by Molmil
X-ray Structure of the MMTV-A Nucleosome Core Particle
Descriptor: CHLORIDE ION, DNA (147-MER), Histone H2A type 1, ...
Authors:Frouws, T.D, Richmond, T.J.
Deposit date:2015-12-09
Release date:2016-02-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:X-ray structure of the MMTV-A nucleosome core.
Proc.Natl.Acad.Sci.USA, 113, 2016
5XF6
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BU of 5xf6 by Molmil
Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having an ethylenediamine linker
Descriptor: DNA (145-MER), ETHANE-1,2-DIAMINE, Histone H2A, ...
Authors:Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
Deposit date:2017-04-07
Release date:2017-10-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
3REI
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BU of 3rei by Molmil
2.65 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 145 bp Alpha-Satellite DNA (NCP145) Derivatized with Triamminechloroplatinum(II) Chloride
Descriptor: DNA (145-MER), Histone H2A type1, Histone H2B 1.1, ...
Authors:Wu, B, Davey, C.A.
Deposit date:2011-04-04
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation.
Nucleic Acids Res., 39, 2011
1M1A
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BU of 1m1a by Molmil
LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA
Descriptor: 3-AMINO-(DIMETHYLPROPYLAMINE), 4-AMINO-(1-METHYLIMIDAZOLE)-2-CARBOXYLIC ACID, 4-AMINO-(1-METHYLPYRROLE)-2-CARBOXYLIC ACID, ...
Authors:Suto, R.K, Edayathumangalam, R.S, White, C.L, Melander, C, Gottesfeld, J.M, Dervan, P.B, Luger, K.
Deposit date:2002-06-18
Release date:2003-02-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands
J.MOL.BIOL., 326, 2003
2NZD
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BU of 2nzd by Molmil
Nucleosome core particle containing 145 bp of DNA
Descriptor: DNA (145-MER), Histone H2B, Histone H3, ...
Authors:Ong, M.S, Richmond, T.J, Davey, C.A.
Deposit date:2006-11-23
Release date:2007-04-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:DNA stretching and extreme kinking in the nucleosome core
J.Mol.Biol., 368, 2007
8PEO
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BU of 8peo by Molmil
H3K36me2 nucleosome-LEDGF/p75 PWWP domain complex
Descriptor: (2R)-2-amino-3-(2-dimethylaminoethylsulfanyl)propanoic acid, Histone H2A, Histone H2B 1.1, ...
Authors:Koutna, E, Kouba, T, Veverka, V.
Deposit date:2023-06-14
Release date:2023-08-16
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Res., 51, 2023
1P3P
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BU of 1p3p by Molmil
Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants
Descriptor: Histone H2A, Histone H2B, Histone H3, ...
Authors:Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K.
Deposit date:2003-04-17
Release date:2004-02-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
1P34
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BU of 1p34 by Molmil
Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants
Descriptor: Histone H2A, Histone H2B, Histone H3, ...
Authors:Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K.
Deposit date:2003-04-17
Release date:2004-02-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
6N1Z
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BU of 6n1z by Molmil
Importin-9 bound to H2A-H2B
Descriptor: Histone H2A, Histone H2B 1.1, Importin-9
Authors:Tomchick, D.R, Chook, Y.M, Padavannil, A.
Deposit date:2018-11-12
Release date:2019-03-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Importin-9 wraps around the H2A-H2B core to act as nuclear importer and histone chaperone.
Elife, 8, 2019
1P3G
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BU of 1p3g by Molmil
Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants
Descriptor: Histone H2A, Histone H2B, Histone H3, ...
Authors:Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K.
Deposit date:2003-04-17
Release date:2004-02-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
3REL
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BU of 3rel by Molmil
2.7 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp Alpha-Satellite DNA (NCP146b) Derivatized with Triamminechloroplatinum(II) Chloride
Descriptor: DNA (146-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Wu, B, Davey, C.A.
Deposit date:2011-04-04
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation.
Nucleic Acids Res., 39, 2011
8CWW
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BU of 8cww by Molmil
Structure of S. cerevisiae Hop1 CBR bound to a nucleosome
Descriptor: Histone H2A, Histone H2B, Histone H3, ...
Authors:Gu, Y, Ur, S.N, Milano, C.R, Tromer, E.C, Vale-Silva, L.A, Hochwagen, A, Corbett, K.D.
Deposit date:2022-05-19
Release date:2023-06-07
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (2.74 Å)
Cite:Chromatin binding by HORMAD proteins regulates meiotic recombination initiation.
Embo J., 43, 2024
3LJA
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BU of 3lja by Molmil
Using Soft X-Rays for a Detailed Picture of Divalent Metal Binding in the Nucleosome
Descriptor: 147mer DNA, Histone H2A, Histone H2B 1.1, ...
Authors:Wu, B, Davey, C.A.
Deposit date:2010-01-26
Release date:2010-04-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Using soft X-rays for a detailed picture of divalent metal binding in the nucleosome
J.Mol.Biol., 398, 2010
1P3O
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BU of 1p3o by Molmil
Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants
Descriptor: Histone H2A, Histone H2B, Histone H3, ...
Authors:Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K.
Deposit date:2003-04-17
Release date:2004-02-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
5ONG
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BU of 5ong by Molmil
X-Ray crystal structure of a nucleosome core particle with its DNA site-specifically crosslinked to the histone octamer
Descriptor: CHLORIDE ION, DNA (147-MER), Histone H2A, ...
Authors:Frouws, T.D, Barth, P.D, Richmond, T.J.
Deposit date:2017-08-03
Release date:2017-11-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.797 Å)
Cite:Site-Specific Disulfide Crosslinked Nucleosomes with Enhanced Stability.
J. Mol. Biol., 430, 2018
6WZ9
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BU of 6wz9 by Molmil
Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin
Descriptor: DNA, Histone H2A, Histone H2B 1.1, ...
Authors:Halic, M, Bilokapic, S.
Deposit date:2020-05-13
Release date:2020-09-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin.
Nature, 585, 2020
5MLU
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BU of 5mlu by Molmil
Crystal structure of the PFV GAG CBS bound to a mononucleosome
Descriptor: DNA (145-MER), Histone H2A type 1, Histone H2B, ...
Authors:Pye, V.E, Maskell, D.P, Lesbats, P, Cherepanov, P.
Deposit date:2016-12-07
Release date:2017-05-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for spumavirus GAG tethering to chromatin.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7YI1
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BU of 7yi1 by Molmil
Cryo-EM structure of Eaf3 CHD bound to H3K36me3 nucleosome
Descriptor: Chromatin modification-related protein EAF3, Histone H2A, Histone H2B 1.1, ...
Authors:Li, H.T, Yan, C.Y, Guan, H.P, Wang, P.
Deposit date:2022-07-14
Release date:2023-06-14
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.
Nature, 620, 2023

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