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PDB: 1846 results

8AQV
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BA.2.12.1 SARS-CoV-2 Spike bound to mouse ACE2 (local)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2,Ig gamma-2A chain C region, ...
Authors:Lau, K, Ni, D, Beckert, B, Nazarov, S, Myasnikov, A, Pojer, F, Stahlberg, H, Uchikawa, E.
Deposit date:2022-08-13
Release date:2023-03-01
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Cryo-EM structures and binding of mouse and human ACE2 to SARS-CoV-2 variants of concern indicate that mutations enabling immune escape could expand host range.
Plos Pathog., 19, 2023
7FJC
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Crystal structure of SARS-CoV-2 Beta RBD complexed with P36-5D2 Fab
Descriptor: P36-5D2 heavy chain, P36-5D2 light chain, Spike protein S1, ...
Authors:Zhang, L.Q, Wang, X.Q, Shan, S.S, Lan, J.
Deposit date:2021-08-03
Release date:2022-08-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Crystal structure of SARS-CoV-2 Beta RBD complexed with P36-5D2 Fab
To Be Published
7MW2
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Structure of the SARS-CoV-2 Spike trimer with all RBDs down in complex with the Fab fragment of human neutralizing antibody clone 6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab of antibody clone 6, ...
Authors:Hu, Y, Xiong, Y.
Deposit date:2021-05-15
Release date:2022-03-16
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617.
Nat Commun, 13, 2022
7L2E
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BU of 7l2e by Molmil
Cryo-EM structure of NTD-directed neutralizing antibody 4-18 in complex with prefusion SARS-CoV-2 spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-18 heavy chain, ...
Authors:Cerutti, G, Shapiro, L.
Deposit date:2020-12-16
Release date:2021-03-24
Last modified:2021-05-26
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.
Cell Host Microbe, 29, 2021
7LAB
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BU of 7lab by Molmil
Structure of SARS-CoV-2 S protein in complex with N-terminal domain antibody DH1052
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1052 heavy chain, ...
Authors:Manne, K, Acharya, P.
Deposit date:2021-01-06
Release date:2021-03-10
Last modified:2021-08-18
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies.
Cell, 184, 2021
7P77
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BU of 7p77 by Molmil
SARS-CoV-2 spike protein in complex with sybody#15 and sybody#68 in a 3up conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(5-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Walter, J.D, Hutter, C.A.J, Garaeva, A.A, Scherer, M, Zimmermann, I, Wyss, M, Rheinberger, J, Ruedin, Y, Earp, J.C, Egloff, P, Sorgenfrei, M, Huerlimann, L.M, Gonda, I, Meier, G, Remm, S, Thavarasah, S, Zimmer, G, Slotboom, D.J, Paulino, C, Plattet, P, Seeger, M.A.
Deposit date:2021-07-19
Release date:2021-08-04
Last modified:2022-04-20
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance.
Embo Rep., 23, 2022
7WLZ
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BU of 7wlz by Molmil
Cryo-EM structure of the Omicron S in complex with 35B5 Fab(1 down-, 1 up- and 1 invisible RBDs)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ...
Authors:Wang, X, Zhu, Y.
Deposit date:2022-01-14
Release date:2022-05-25
Last modified:2022-06-22
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:35B5 antibody potently neutralizes SARS-CoV-2 Omicron by disrupting the N-glycan switch via a conserved spike epitope.
Cell Host Microbe, 30, 2022
8HFX
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BU of 8hfx by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron BA.1 spike protein in complex with white-tailed deer ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ...
Authors:Han, P, Meng, Y.M, Qi, J.X.
Deposit date:2022-11-13
Release date:2023-08-30
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Structural basis of white-tailed deer, Odocoileus virginianus , ACE2 recognizing all the SARS-CoV-2 variants of concern with high affinity.
J.Virol., 97, 2023
7B0B
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BU of 7b0b by Molmil
Fab HbnC3t1p1_C6 bound to SARS-CoV-2 RBD
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, IGK@ protein, ...
Authors:Borenstein-Katz, A, Diskin, R.
Deposit date:2020-11-19
Release date:2021-12-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Somatic hypermutation introduces bystander mutations that prepare SARS-CoV-2 antibodies for emerging variants.
Immunity, 56, 2023
8Y16
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BU of 8y16 by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron JN.1 spike protein in complex with human ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Li, L.J, Gu, Y.H, Qi, J.X, Gao, G.F.
Deposit date:2024-01-23
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Spike structures, receptor binding and immune escape of SARS-CoV-2 Omicron recently-circulating BA.2.86.1, JN.1, EG.5, EG.5.1 and HV.1 sub-variants
To Be Published
7XDA
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Cryo-EM structure of SARS-CoV-2 Delta RBD in complex with BA7208 and BA7125 fab (local refinement)
Descriptor: BA7125 fab, BA7208 fab, Spike glycoprotein
Authors:Liu, Z, Liu, S, Liu, S.
Deposit date:2022-03-26
Release date:2023-03-01
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Biparatopic antibody BA7208/7125 effectively neutralizes SARS-CoV-2 variants including Omicron BA.1-BA.5.
Cell Discov, 9, 2023
7YD1
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BU of 7yd1 by Molmil
Local refinement of SARS-CoV-2 Omicron S trimer complexed with XG005
Descriptor: Spike protein S1, XG005-VH, XG005-VL
Authors:Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L.
Deposit date:2022-07-02
Release date:2023-07-12
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:OS-XG005
To be Published
7PS2
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BU of 7ps2 by Molmil
Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-29 and Beta-53 Fabs
Descriptor: Beta-29 Fab heavy chain, Beta-29 Fab light chain, Beta-53 Fab light chain, ...
Authors:Zhou, D, Ren, J, Stuart, D.I.
Deposit date:2021-09-22
Release date:2021-12-15
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants.
Cell Host Microbe, 30, 2022
7E3J
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BU of 7e3j by Molmil
Crystal structure of SARS-CoV-2 RBD binding to dog ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACE2, Spike protein S1, ...
Authors:Zhang, Z, Zhang, Y.
Deposit date:2021-02-08
Release date:2021-04-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:The molecular basis for SARS-CoV-2 binding to dog ACE2.
Nat Commun, 12, 2021
7XH8
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BU of 7xh8 by Molmil
The structure of ZCB11 Fab against SARS-CoV-2 Omicron Spike
Descriptor: Spike glycoprotein, The heavy chain of ZCB11 antibody, The light chain of ZCB11 antibody
Authors:Hang, L, Dang, S.
Deposit date:2022-04-07
Release date:2022-06-29
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:A broadly neutralizing antibody protects Syrian hamsters against SARS-CoV-2 Omicron challenge.
Nat Commun, 13, 2022
9AYW
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BU of 9ayw by Molmil
SARS-CoV-2 Omicron-EG.5.1 3-RBD down Spike Protein Trimer 1 (S-GSAS-Omicron-EG.5.1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Zhang, Q.E, Acharya, P.
Deposit date:2024-03-08
Release date:2024-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:SARS-CoV-2 Omicron-EG.5.1 3-RBD down Spike Protein Trimer 1 (S-GSAS-Omicron-EG.5.1)
To Be Published
9AYX
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SARS-CoV-2 Omicron-EG.5.1 3-RBD down Spike Protein Trimer 2 (S-GSAS-Omicron-EG.5.1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Zhang, Q.E, Acharya, P.
Deposit date:2024-03-08
Release date:2024-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:SARS-CoV-2 Omicron-EG.5.1 3-RBD down Spike Protein Trimer 2 (S-GSAS-Omicron-EG.5.1)
To Be Published
7Y9S
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BU of 7y9s by Molmil
Cryo-EM structure of apo SARS-CoV-2 Omicron spike protein (S-2P-GSAS)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Zhao, Z.N, Xie, Y.F, Qi, J.X, Gao, G.F.
Deposit date:2022-06-26
Release date:2022-08-31
Last modified:2022-09-07
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape.
Nat Commun, 13, 2022
7XU1
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BU of 7xu1 by Molmil
Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-122 Conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ...
Authors:Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G.
Deposit date:2022-05-18
Release date:2022-07-20
Last modified:2022-08-17
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike.
Plos Pathog., 18, 2022
7XU3
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BU of 7xu3 by Molmil
Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Closed Conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ...
Authors:Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G.
Deposit date:2022-05-18
Release date:2022-07-20
Last modified:2022-08-17
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike.
Plos Pathog., 18, 2022
7UHB
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BU of 7uhb by Molmil
SARS-CoV-2 spike in complex with AHB2-2GS-SB175 (local refinement of the RBD and AHB2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Multivalent miniprotein inhibitor AHB2-2GS-SB175, Spike glycoprotein
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2022-03-26
Release date:2022-06-08
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice.
Sci Transl Med, 14, 2022
7C8D
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BU of 7c8d by Molmil
Cryo-EM structure of cat ACE2 and SARS-CoV-2 RBD
Descriptor: Angiotensin-converting enzyme 2, Spike protein S1, ZINC ION
Authors:Gao, G.F, Wang, Q.H, Wu, L.l.
Deposit date:2020-05-29
Release date:2020-09-02
Last modified:2020-12-02
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Broad host range of SARS-CoV-2 and the molecular basis for SARS-CoV-2 binding to cat ACE2.
Cell Discov, 6, 2020
7PBE
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BU of 7pbe by Molmil
Emergence of immune escape at dominant SARS-CoV-2 killer T-cell epitope
Descriptor: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, Human T-cell Receptor YLQ36, ...
Authors:Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A.
Deposit date:2021-08-02
Release date:2022-04-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope.
Cell, 185, 2022
8KHC
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BU of 8khc by Molmil
SARS-CoV-2 Omicron spike in complex with 5817 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 5817 Fab, ...
Authors:Cao, L, Wang, X.
Deposit date:2023-08-21
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain.
Cell Rep, 43, 2024
8CIM
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BU of 8cim by Molmil
BA.2-07 FAB IN COMPLEX WITH SARS-COV-2 BA.2.12.1 SPIKE GLYCOPROTEIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BA.2-07 FAB HEAVY CHAIN, ...
Authors:Duyvesteyn, H.M.E, Ren, J, Stuart, D.I, Fry, E.E.
Deposit date:2023-02-10
Release date:2023-07-05
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Isolation of a pair of potent broadly neutralizing mAb binding to RBD and SD1 domains of SARS-CoV-2
Res Sq, 2023

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PDB entries from 2024-07-10

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