7WLZ

Cryo-EM structure of the Omicron S in complex with 35B5 Fab(1 down-, 1 up- and 1 invisible RBDs)

Summary for 7WLZ

Entry DOI	10.2210/pdb7wlz/pdb
EMDB information	32595
Descriptor	Spike glycoprotein, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ... (4 entities in total)
Functional Keywords	viral protein, immune system
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	5
Total formula weight	482776.03
Authors	Wang, X.,Zhu, Y. (deposition date: 2022-01-14, release date: 2022-05-25, Last modification date: 2022-06-22)
Primary citation	Wang, X.,Chen, X.,Tan, J.,Yue, S.,Zhou, R.,Xu, Y.,Lin, Y.,Yang, Y.,Zhou, Y.,Deng, K.,Chen, Z.,Ye, L.,Zhu, Y. 35B5 antibody potently neutralizes SARS-CoV-2 Omicron by disrupting the N-glycan switch via a conserved spike epitope. Cell Host Microbe, 30:887-, 2022 Cited by PubMed: 35436443 DOI: 10.1016/j.chom.2022.03.035 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.98 Å)

Structure validation