2A14
| Crystal Structure of Human Indolethylamine N-methyltransferase with SAH | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, indolethylamine N-methyltransferase | Authors: | Dong, A, Wu, H, Zeng, H, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | Deposit date: | 2005-06-17 | Release date: | 2005-06-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Crystal Structure of Human Indolethylamine
N-methyltransferase in complex with SAH. To be Published
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2A15
| X-ray Crystal Structure of RV0760 from Mycobacterium Tuberculosis at 1.68 Angstrom Resolution | Descriptor: | HYPOTHETICAL PROTEIN Rv0760c, NICOTINAMIDE | Authors: | Garen, C.R, Cherney, M.M, James, M.N.G, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2005-06-17 | Release date: | 2005-10-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Crystal structure of Mycobacterium tuberculosis Rv0760c at 1.50 A resolution, a structural homolog of Delta(5)-3-ketosteroid isomerase Biochim.Biophys.Acta, 1784, 2008
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2A18
| carboxysome shell protein ccmK4, crystal form 2 | Descriptor: | AMMONIUM ION, Carbon dioxide concentrating mechanism protein ccmK homolog 4 | Authors: | Kerfeld, C.A, Sawaya, M.R, Tanaka, S, Nguyen, C.V, Phillips, M, Beeby, M, Yeates, T.O. | Deposit date: | 2005-06-18 | Release date: | 2005-08-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Protein structures forming the shell of primitive bacterial organelles Science, 309, 2005
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2A19
| PKR kinase domain- eIF2alpha- AMP-PNP complex. | Descriptor: | Eukaryotic translation initiation factor 2 alpha subunit, Interferon-induced, double-stranded RNA-activated protein kinase, ... | Authors: | Dar, A.C, Dever, T.E, Sicheri, F. | Deposit date: | 2005-06-19 | Release date: | 2005-09-27 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Higher-Order Substrate Recognition of eIF2alpha by the RNA-Dependent Protein Kinase PKR. Cell(Cambridge,Mass.), 122, 2005
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2A1A
| PKR kinase domain-eIF2alpha Complex | Descriptor: | Eukaryotic translation initiation factor 2 alpha subunit, Interferon-induced, double-stranded RNA-activated protein kinase | Authors: | Dar, A.C, Dever, T.E, Sicheri, F. | Deposit date: | 2005-06-19 | Release date: | 2005-09-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Higher-Order Substrate Recognition of eIF2alpha by the RNA-Dependent Protein Kinase PKR. Cell(Cambridge,Mass.), 122, 2005
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2A1B
| Carboxysome shell protein ccmK2 | Descriptor: | Carbon dioxide concentrating mechanism protein ccmK homolog 2 | Authors: | Kerfeld, C.A, Sawaya, M.R, Tanaka, S, Nguyen, C.V, Phillips, M, Beeby, M, Yeates, T.O. | Deposit date: | 2005-06-20 | Release date: | 2005-08-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Protein structures forming the shell of primitive bacterial organelles Science, 309, 2005
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2A1C
| Solution structure of CSP1 | Descriptor: | CSP1 | Authors: | Johnsborg, O, Kristiansen, P.E. | Deposit date: | 2005-06-20 | Release date: | 2006-05-30 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | A Hydrophobic Patch in the Pneumococcal Competence Pheromone CSP is Essential for Specificity and Biological Activity To be Published
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2A1D
| Staphylocoagulase bound to bovine thrombin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, SODIUM ION, ... | Authors: | Friedrich, R, Panizzi, P, Kawabata, S, Bode, W, Bock, P.E, Fuentes-Prior, P. | Deposit date: | 2005-06-20 | Release date: | 2005-09-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural Basis for Reduced Staphylocoagulase-mediated Bovine Prothrombin Activation J.Biol.Chem., 281, 2006
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2A1E
| High resolution structure of HIV-1 PR with TS-126 | Descriptor: | ACETATE ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | Authors: | Demitri, N, Geremia, S, Randaccio, L, Wuerges, J, Benedetti, F, Berti, F, Dinon, F, Campaner, P, Tell, G. | Deposit date: | 2005-06-20 | Release date: | 2006-02-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | A potent HIV protease inhibitor identified in an epimeric mixture by high-resolution protein crystallography. Chemmedchem, 1, 2006
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2A1F
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2A1H
| X-ray crystal structure of human mitochondrial branched chain aminotransferase (BCATm) complexed with gabapentin | Descriptor: | ACETIC ACID, PYRIDOXAL-5'-PHOSPHATE, [1-(AMINOMETHYL)CYCLOHEXYL]ACETIC ACID, ... | Authors: | Goto, M, Miyahara, I, Hirotsu, K, Conway, M, Yennawar, N, Islam, M.M, Hutson, S.M. | Deposit date: | 2005-06-20 | Release date: | 2005-09-06 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin. J.Biol.Chem., 280, 2005
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2A1I
| Crystal Structure of the Central Domain of Human ERCC1 | Descriptor: | DNA excision repair protein ERCC-1, MERCURY (II) ION | Authors: | Tsodikov, O.V, Enzlin, J.H, Scharer, O.D, Ellenberger, T. | Deposit date: | 2005-06-20 | Release date: | 2005-08-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1. Proc.Natl.Acad.Sci.Usa, 102, 2005
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2A1J
| Crystal Structure of the Complex between the C-Terminal Domains of Human XPF and ERCC1 | Descriptor: | DNA excision repair protein ERCC-1, DNA repair endonuclease XPF, MERCURY (II) ION | Authors: | Tsodikov, O.V, Enzlin, J.H, Scharer, O.D, Ellenberger, T. | Deposit date: | 2005-06-20 | Release date: | 2005-08-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1. Proc.Natl.Acad.Sci.Usa, 102, 2005
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2A1K
| RB69 single-stranded DNA binding protein core domain | Descriptor: | ZINC ION, gp32 single stranded DNA binding protein | Authors: | Sun, S, Geng, L, Shamoo, Y. | Deposit date: | 2005-06-20 | Release date: | 2006-05-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and enzymatic properties of a chimeric bacteriophage RB69 DNA polymerase and single-stranded DNA binding protein with increased processivity. Proteins, 65, 2006
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2A1L
| Rat PITP-Beta Complexed to Phosphatidylcholine | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Phosphatidylinositol transfer protein beta isoform | Authors: | Vordtriede, P.B, Doan, C.N, Tremblay, J.M, Helmkamp, G.M, Yoder, M.D. | Deposit date: | 2005-06-20 | Release date: | 2005-11-29 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Structure of PITPbeta in Complex with Phosphatidylcholine: Comparison of Structure and Lipid Transfer to Other PITP Isoforms. Biochemistry, 44, 2005
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2A1M
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2A1N
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2A1O
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2A1R
| Crystal structure of PARN nuclease domain | Descriptor: | 5'-R(*AP*AP*A)-3', Poly(A)-specific ribonuclease PARN | Authors: | Wu, M, Song, H. | Deposit date: | 2005-06-21 | Release date: | 2005-12-20 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insight into poly(A) binding and catalytic mechanism of human PARN Embo J., 24, 2005
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2A1S
| Crystal structure of native PARN nuclease domain | Descriptor: | Poly(A)-specific ribonuclease PARN | Authors: | Wu, M, Song, H. | Deposit date: | 2005-06-21 | Release date: | 2005-12-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insight into poly(A) binding and catalytic mechanism of human PARN Embo J., 24, 2005
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2A1T
| Structure of the human MCAD:ETF E165betaA complex | Descriptor: | ADENOSINE MONOPHOSPHATE, Acyl-CoA dehydrogenase, medium-chain specific, ... | Authors: | Toogood, H.S, Van Thiel, A, Scrutton, N.S, Leys, D. | Deposit date: | 2005-06-21 | Release date: | 2005-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Stabilization of Non-productive Conformations Underpins Rapid Electron Transfer to Electron-transferring Flavoprotein J.Biol.Chem., 280, 2005
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2A1U
| Crystal structure of the human ETF E165betaA mutant | Descriptor: | ADENOSINE MONOPHOSPHATE, Electron transfer flavoprotein alpha-subunit, mitochondrial precursor, ... | Authors: | Toogood, H.S, Van Thiel, A, Scrutton, N.S, Leys, D. | Deposit date: | 2005-06-21 | Release date: | 2005-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Stabilization of Non-productive Conformations Underpins Rapid Electron Transfer to Electron-transferring Flavoprotein J.Biol.Chem., 280, 2005
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2A1V
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2A1W
| Anti-cocaine antibody 7.5.21, crystal form I | Descriptor: | SULFATE ION, immunoglobulin heavy chain, immunoglobulin light chain kappa | Authors: | Pozharski, E, Hewagama, A, Shanafelt, A, Ringe, D, Petsko, G.A. | Deposit date: | 2005-06-21 | Release date: | 2005-06-28 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Flexibility Of Packing:
Four Crystal Forms Of An Anti-Cocaine Antibody 7.5.21 To be Published
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2A1X
| Human phytanoyl-coa 2-hydroxylase in complex with iron and 2-oxoglutarate | Descriptor: | 2-OXOGLUTARIC ACID, FE (II) ION, Phytanoyl-CoA dioxygenase | Authors: | Kavanagh, K.L, McDonough, M.A, Searles, T, Butler, D, Bunkoczi, G, von Delft, F, Edwards, A, Arrowsmith, C, Sundstrom, M, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC) | Deposit date: | 2005-06-21 | Release date: | 2005-08-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of Human Phytanoyl-CoA 2-Hydroxylase Identifies Molecular Mechanisms of Refsum Disease J.Biol.Chem., 280, 2005
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