Crystal structure of the human ETF E165betaA mutant

Summary for 2A1U

Related1EFV 1T9G 2A1T
DescriptorElectron transfer flavoprotein alpha-subunit, mitochondrial precursor, Electron transfer flavoprotein beta-subunit, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total)
Functional Keywordselectron transfer, mobile domain, conformational sampling, electron transport
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight64081.89
Toogood, H.S.,Van Thiel, A.,Scrutton, N.S.,Leys, D. (deposition date: 2005-06-21, release date: 2005-07-05, Last modification date: 2018-10-03)
Primary citation
Toogood, H.S.,van Thiel, A.,Scrutton, N.S.,Leys, D.
Stabilization of Non-productive Conformations Underpins Rapid Electron Transfer to Electron-transferring Flavoprotein
J.Biol.Chem., 280:30361-30366, 2005
PubMed: 15975918 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M505562200
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24950.2%3.9%1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report