Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 291 件

3J7V
DownloadVisualize
BU of 3j7v by Molmil
Capsid Expansion Mechanism Of Bacteriophage T7 Revealed By Multi-State Atomic Models Derived From Cryo-EM Reconstructions
分子名称: Major capsid protein 10A
著者Guo, F, Liu, Z, Fang, P.A, Zhang, Q, Wright, E.T, Wu, W, Zhang, C, Vago, F, Ren, Y, Jakata, J, Chiu, W, Serwer, P, Jiang, W.
登録日2014-08-12
公開日2014-10-15
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Capsid expansion mechanism of bacteriophage T7 revealed by multistate atomic models derived from cryo-EM reconstructions.
Proc.Natl.Acad.Sci.USA, 111, 2014
3J7W
DownloadVisualize
BU of 3j7w by Molmil
Capsid Expansion Mechanism Of Bacteriophage T7 Revealed By Multi-State Atomic Models Derived From Cryo-EM Reconstructions
分子名称: Major capsid protein 10A
著者Guo, F, Liu, Z, Fang, P.A, Zhang, Q, Wright, E.T, Wu, W, Zhang, C, Vago, F, Ren, Y, Jakata, J, Chiu, W, Serwer, P, Jiang, W.
登録日2014-08-12
公開日2014-10-15
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Capsid expansion mechanism of bacteriophage T7 revealed by multistate atomic models derived from cryo-EM reconstructions.
Proc.Natl.Acad.Sci.USA, 111, 2014
6NT6
DownloadVisualize
BU of 6nt6 by Molmil
Cryo-EM structure of full-length chicken STING in the apo state
分子名称: Stimulator of interferon genes protein
著者Shang, G, Zhang, C, Chen, Z.J, Bai, X, Zhang, X.
登録日2019-01-28
公開日2019-03-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP.
Nature, 567, 2019
6NT5
DownloadVisualize
BU of 6nt5 by Molmil
Cryo-EM structure of full-length human STING in the apo state
分子名称: Stimulator of interferon protein
著者Shang, G, Zhang, C, Chen, Z.J, Bai, X, Zhang, X.
登録日2019-01-28
公開日2019-03-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP.
Nature, 567, 2019
3J7X
DownloadVisualize
BU of 3j7x by Molmil
Capsid Expansion Mechanism Of Bacteriophage T7 Revealed By Multi-State Atomic Models Derived From Cryo-EM Reconstructions
分子名称: Major capsid protein 10A
著者Guo, F, Liu, Z, Fang, P.A, Zhang, Q, Wright, E.T, Wu, W, Zhang, C, Vago, F, Ren, Y, Jakata, J, Chiu, W, Serwer, P, Jiang, W.
登録日2014-08-12
公開日2014-10-15
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Capsid expansion mechanism of bacteriophage T7 revealed by multistate atomic models derived from cryo-EM reconstructions.
Proc.Natl.Acad.Sci.USA, 111, 2014
6OMM
DownloadVisualize
BU of 6omm by Molmil
Cryo-EM structure of formyl peptide receptor 2/lipoxin A4 receptor in complex with Gi
分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhuang, Y, Liu, H, de Waal, P.W, Zhou, X.E, Wang, L, Meng, X, Zhao, G, Kang, Y, Melcher, K, Xu, H.E, Zhang, C.
登録日2019-04-19
公開日2020-02-26
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Structure of formylpeptide receptor 2-Gicomplex reveals insights into ligand recognition and signaling.
Nat Commun, 11, 2020
6NSQ
DownloadVisualize
BU of 6nsq by Molmil
Crystal structure of BRAF kinase domain bound to the inhibitor 2l
分子名称: 5-[(4-amino-1-ethyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)ethynyl]-N-(4-chlorophenyl)-6-methylisoquinolin-1-amine, Serine/threonine-protein kinase B-raf
著者Maisonneuve, P, Kurinov, I, Assadieskandar, A, Yu, C, Zhang, C, Sicheri, F.
登録日2019-01-25
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Rigidification Dramatically Improves Inhibitor Selectivity for RAF Kinases.
Acs Med.Chem.Lett., 10, 2019
4IH1
DownloadVisualize
BU of 4ih1 by Molmil
Crystal structure of Karrikin Insensitive 2 (KAI2) from Arabidopsis thaliana
分子名称: Hydrolase, alpha/beta fold family protein
著者Zhou, X.E, Zhao, L.-H, Wu, Z.-S, Yi, W, Li, S, Li, Y, Xu, Y, Xu, T.-H, Liu, Y, Chen, R.-Z, Kovach, A, Kang, Y, Hou, L, He, Y, Zhang, C, Melcher, K, Xu, H.E.
登録日2012-12-18
公開日2013-01-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.
Cell Res., 23, 2013
4IH9
DownloadVisualize
BU of 4ih9 by Molmil
Crystal structure of rice DWARF14 (D14)
分子名称: Dwarf 88 esterase
著者Zhou, X.E, Zhao, L.-H, Wu, Z.-S, Yi, W, Li, S, Li, Y, Xu, Y, Xu, T.-H, Liu, Y, Chen, R.-Z, Kovach, A, Kang, Y, Hou, L, He, Y, Zhang, C, Melcher, K, Xu, H.E.
登録日2012-12-18
公開日2013-01-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.
Cell Res., 23, 2013
4IHA
DownloadVisualize
BU of 4iha by Molmil
Crystal structure of rice DWARF14 (D14) in complex with a GR24 hydrolysis intermediate
分子名称: (2R,3R)-2,4,4-trihydroxy-3-methylbutanal, Dwarf 88 esterase
著者Zhou, X.E, Zhao, L.-H, Wu, Z.-S, Yi, W, Li, S, Li, Y, Xu, Y, Xu, T.-H, Liu, Y, Chen, R.-Z, Kovach, A, Kang, Y, Hou, L, He, Y, Zhang, C, Melcher, K, Xu, H.E.
登録日2012-12-18
公開日2013-01-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.
Cell Res., 23, 2013
4IH4
DownloadVisualize
BU of 4ih4 by Molmil
Crystal structure of Arabidopsis DWARF14 orthologue, AtD14
分子名称: AT3g03990/T11I18_10
著者Zhou, X.E, Zhao, L.-H, Wu, Z.-S, Yi, W, Li, S, Li, Y, Xu, Y, Xu, T.-H, Liu, Y, Chen, R.-Z, Kovach, A, Kang, Y, Hou, L, He, Y, Zhang, C, Melcher, K, Xu, H.E.
登録日2012-12-18
公開日2013-01-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.
Cell Res., 23, 2013
5FBH
DownloadVisualize
BU of 5fbh by Molmil
Crystal structure of the extracellular domain of human calcium sensing receptor with bound Gd3+
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, CHLORIDE ION, ...
著者Zhang, T, Zhang, C, Miller, C.L, Zou, J, Moremen, K.W, Brown, E.M, Yang, J.J, Hu, J.
登録日2015-12-14
公開日2016-06-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist.
Sci Adv, 2, 2016
8G4G
DownloadVisualize
BU of 8g4g by Molmil
Crystal Engineering with One 8-mer DNA
分子名称: DNA (5'-D(*AP*TP*CP*GP*G)-3'), DNA (5'-D(*AP*TP*CP*GP*GP*CP*CP*G)-3'), DNA (5'-D(P*CP*CP*G)-3')
著者Zhao, J, Zhang, C, Lu, B, Seeman, N.C, Noinaj, N, Sha, R, Mao, C.
登録日2023-02-09
公開日2023-05-10
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Divergence and Convergence: Complexity Emerges in Crystal Engineering from an 8-mer DNA.
J.Am.Chem.Soc., 145, 2023
6CAD
DownloadVisualize
BU of 6cad by Molmil
Crystal structure of RAF kinase domain bound to the inhibitor 2a
分子名称: 1-(propan-2-yl)-3-({3-[3-(trifluoromethyl)phenyl]isoquinolin-8-yl}ethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Serine/threonine-protein kinase B-raf
著者Maisonneuve, P, Kurinov, I, Assadieskandar, A, Yu, C, Liu, X, Chen, Y.-C, Prakash, G.K.S, Zhang, C, SIcheri, F.
登録日2018-01-30
公開日2018-02-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Effects of rigidity on the selectivity of protein kinase inhibitors.
Eur J Med Chem, 146, 2018
5L6P
DownloadVisualize
BU of 5l6p by Molmil
EphB3 kinase domain covalently bound to an irreversible inhibitor (compound 6)
分子名称: 1,4-DIETHYLENE DIOXIDE, Ephrin type-B receptor 3, ~{N}-(4-phenylazanylquinazolin-7-yl)ethanamide
著者Schimpl, M, Overman, R, Kung, A, Chen, Y.-C, Ni, F, Zhu, J, Turner, M, Molina, H, Zhang, C.
登録日2016-05-30
公開日2016-08-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Development of Specific, Irreversible Inhibitors for a Receptor Tyrosine Kinase EphB3.
J.Am.Chem.Soc., 138, 2016
5L6O
DownloadVisualize
BU of 5l6o by Molmil
EphB3 kinase domain covalently bound to an irreversible inhibitor (compound 3)
分子名称: 1,4-DIETHYLENE DIOXIDE, 1-(4-phenylazanylquinazolin-7-yl)ethanone, Ephrin type-B receptor 3
著者Schimpl, M, Overman, R, Kung, A, Chen, Y.-C, Ni, F, Zhu, J, Turner, M, Molina, H, Zhang, C.
登録日2016-05-30
公開日2016-08-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Development of Specific, Irreversible Inhibitors for a Receptor Tyrosine Kinase EphB3.
J.Am.Chem.Soc., 138, 2016
2LSR
DownloadVisualize
BU of 2lsr by Molmil
Solution structure of harmonin N terminal domain in complex with a exon68 encoded peptide of cadherin23
分子名称: Harmonin, peptide from Cadherin-23
著者Pan, L, Wu, L, Zhang, C, Zhang, M.
登録日2012-05-04
公開日2012-08-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Large protein assemblies formed by multivalent interactions between cadherin23 and harmonin suggest a stable anchorage structure at the tip link of stereocilia.
J.Biol.Chem., 287, 2012
3MA6
DownloadVisualize
BU of 3ma6 by Molmil
Crystal structure of kinase domain of TgCDPK1 in presence of 3BrB-PP1
分子名称: 3-(3-bromobenzyl)-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1
著者Wernimont, A.K, Qiu, W, Amani, M, Artz, J.D, Hassani, A.A, Senisterra, G, Vedadi, M, Sibley, L.D, Lourido, S, Shokat, K, Zhang, C, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Hui, R, Lin, Y.H, Structural Genomics Consortium (SGC)
登録日2010-03-23
公開日2010-07-21
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of kinase domain of TgCDPK1 in presence of 3BrB-PP1
To be Published
7CFN
DownloadVisualize
BU of 7cfn by Molmil
Cryo-EM structure of the INT-777-bound GPBAR-Gs complex
分子名称: (2S,4R)-4-[(3R,5S,6R,7R,8R,9S,10S,12S,13R,14S,17R)-6-ethyl-10,13-dimethyl-3,7,12-tris(oxidanyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-pentanoic acid, CHOLESTEROL, G-protein coupled bile acid receptor 1, ...
著者Yang, F, Mao, C, Guo, L, Lin, J, Ming, Q, Xiao, P, Wu, X, Shen, Q, Guo, S, Shen, D, Lu, R, Zhang, L, Huang, S, Ping, Y, Zhang, C, Ma, C, Zhang, K, Liang, X, Shen, Y, Nan, F, Yi, F, Luca, V, Zhou, J, Jiang, C, Sun, J, Xie, X, Yu, X, Zhang, Y.
登録日2020-06-27
公開日2020-09-09
最終更新日2021-04-07
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of GPBAR activation and bile acid recognition.
Nature, 587, 2020
7CFM
DownloadVisualize
BU of 7cfm by Molmil
Cryo-EM structure of the P395-bound GPBAR-Gs complex
分子名称: 2-(ethylamino)-6-[3-(4-propan-2-ylphenyl)propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide, CHOLESTEROL, G-protein coupled bile acid receptor 1, ...
著者Yang, F, Mao, C, Guo, L, Lin, J, Ming, Q, Xiao, P, Wu, X, Shen, Q, Guo, S, Shen, D, Lu, R, Zhang, L, Huang, S, Ping, Y, Zhang, C, Ma, C, Zhang, K, Liang, X, Shen, Y, Nan, F, Yi, F, Luca, V, Zhou, J, Jiang, C, Sun, J, Xie, X, Yu, X, Zhang, Y.
登録日2020-06-27
公開日2020-09-09
最終更新日2020-12-02
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of GPBAR activation and bile acid recognition.
Nature, 587, 2020
7CX4
DownloadVisualize
BU of 7cx4 by Molmil
Cryo-EM structure of the Evatanepag-bound EP2-Gs complex
分子名称: 2-[3-[[(4-~{tert}-butylphenyl)methyl-pyridin-3-ylsulfonyl-amino]methyl]phenoxy]ethanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Qu, C, Mao, C, Xiao, P, Shen, Q, Zhong, Y, Yang, F, Shen, D, Tao, X, Zhang, H, Yan, X, Zhao, R, He, J, Guan, Y, Zhang, C, Hou, G, Zhang, P, Yu, X, Guan, Y, Sun, J, Zhang, Y.
登録日2020-09-01
公開日2021-05-05
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E 2 receptor EP2 subtype.
Sci Adv, 7, 2021
7CX3
DownloadVisualize
BU of 7cx3 by Molmil
Cryo-EM structure of the Taprenepag-bound EP2-Gs complex
分子名称: 2-[3-[[(4-pyrazol-1-ylphenyl)methyl-pyridin-3-ylsulfonyl-amino]methyl]phenoxy]ethanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Qu, C, Mao, C, Xiao, P, Shen, Q, Zhong, Y, Yang, F, Shen, D, Tao, X, Zhang, H, Yan, X, Zhao, R, He, J, Guan, Y, Zhang, C, Hou, G, Zhang, P, Yu, X, Guan, Y, Sun, J, Zhang, Y.
登録日2020-09-01
公開日2021-05-05
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E 2 receptor EP2 subtype.
Sci Adv, 7, 2021
7CX2
DownloadVisualize
BU of 7cx2 by Molmil
Cryo-EM structure of the PGE2-bound EP2-Gs complex
分子名称: (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Qu, C, Mao, C, Xiao, P, Shen, Q, Zhong, Y, Yang, F, Shen, D, Tao, X, Zhang, H, Yan, X, Zhao, R, He, J, Guan, Y, Zhang, C, Hou, G, Zhang, P, Yu, X, Guan, Y, Sun, J, Zhang, Y.
登録日2020-09-01
公開日2021-05-05
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E 2 receptor EP2 subtype.
Sci Adv, 7, 2021
8J0N
DownloadVisualize
BU of 8j0n by Molmil
cryo-EM structure of human EMC
分子名称: ER membrane protein complex subunit 1, ER membrane protein complex subunit 10, ER membrane protein complex subunit 2, ...
著者Li, M, Zhang, C, Wu, J, Lei, M.
登録日2023-04-11
公開日2024-04-03
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structural insights into human EMC and its interaction with VDAC.
Aging (Albany NY), 16, 2024
8J0O
DownloadVisualize
BU of 8j0o by Molmil
cryo-EM structure of human EMC and VDAC
分子名称: ER membrane protein complex subunit 1, ER membrane protein complex subunit 10, ER membrane protein complex subunit 2, ...
著者Li, M, Zhang, C, Wu, J, Lei, M.
登録日2023-04-11
公開日2024-04-03
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Structural insights into human EMC and its interaction with VDAC.
Aging (Albany NY), 16, 2024

221051

件を2024-06-12に公開中

PDB statisticsPDBj update infoContact PDBjnumon