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PDB: 288 件

8W6P
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Crystal structure of dimeric murine SMPDL3A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3a, ...
著者Zhang, C, Liu, P, Fan, S, Hou, Y.
登録日2023-08-29
公開日2023-12-20
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing.
Immunity, 56, 2023
8W6R
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murine SMPDL3A bound to sulfate
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3a, ...
著者Zhang, C, Liu, P, Fan, S.
登録日2023-08-29
公開日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing.
Immunity, 56, 2023
8EPD
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Engineering Crystals with Tunable Symmetries from 14- or 16-Base-Long DNA Strands
分子名称: DNA (5'-D(*CP*GP*AP*CP*G)-3'), DNA (5'-D(P*CP*GP*TP*TP*CP*C)-3'), DNA (5'-D(P*GP*GP*AP*GP*C)-3')
著者Zhang, C, Zhao, J, Lu, B, Sha, R, Seeman, N.C, Noinaj, N, Mao, C.
登録日2022-10-05
公開日2023-03-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Engineering DNA Crystals toward Studying DNA-Guest Molecule Interactions.
J.Am.Chem.Soc., 145, 2023
8EPG
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Engineering Crystals with Tunable Symmetries from 14- or 16-Base-Long DNA Strands
分子名称: DNA (5'-D(*CP*GP*AP*CP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*C)-3'), DNA (5'-D(P*GP*CP*CP*GP*C)-3')
著者Zhang, C, Zhao, J, Lu, B, Sha, R, Seeman, N.C, Noinaj, N, Mao, C.
登録日2022-10-05
公開日2023-03-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Engineering DNA Crystals toward Studying DNA-Guest Molecule Interactions.
J.Am.Chem.Soc., 145, 2023
8F40
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Engineering Crystals with Tunable Symmetries from 14- or 16-Base-Long DNA Strands
分子名称: DNA (5'-D(*CP*GP*CP*TP*T)-3'), DNA (5'-D(P*AP*AP*GP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*GP*C)-3')
著者Zhang, C, Zhao, J, Lu, B, Sha, R, Seeman, N.C, Noinaj, N, Mao, C.
登録日2022-11-10
公開日2023-03-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Engineering DNA Crystals toward Studying DNA-Guest Molecule Interactions.
J.Am.Chem.Soc., 145, 2023
8EPE
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Engineering Crystals with Tunable Symmetries from 14- or 16-Base-Long DNA Strands
分子名称: DNA (5'-D(*CP*GP*AP*CP*G)-3'), DNA (5'-D(P*CP*CP*CP*GP*C)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*G)-3')
著者Zhang, C, Zhao, J, Lu, B, Sha, R, Seeman, N.C, Noinaj, N, Mao, C.
登録日2022-10-05
公開日2023-03-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Engineering DNA Crystals toward Studying DNA-Guest Molecule Interactions.
J.Am.Chem.Soc., 145, 2023
8EP8
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Engineering Crystals with Tunable Symmetries from 14- or 16-Base-Long DNA Strands
分子名称: DNA (5'-D(*CP*GP*AP*CP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*A)-3'), DNA (5'-D(P*TP*CP*CP*GP*C)-3')
著者Zhang, C, Zhao, J, Lu, B, Sha, R, Seeman, N.C, Noinaj, N, Mao, C.
登録日2022-10-05
公開日2023-03-08
最終更新日2023-03-15
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Engineering DNA Crystals toward Studying DNA-Guest Molecule Interactions.
J.Am.Chem.Soc., 145, 2023
8EPB
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Engineering Crystals with Tunable Symmetries from 14- or 16-Base-Long DNA Strands
分子名称: DNA (5'-D(*CP*GP*CP*TP*GP*GP*TP*GP*GP*TP*TP*CP*GP*A)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*GP*CP*CP*GP*AP*AP*CP*CP*T)-3')
著者Zhang, C, Zhao, J, Lu, B, Sha, R, Seeman, N.C, Noinaj, N, Mao, C.
登録日2022-10-05
公開日2023-03-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Engineering DNA Crystals toward Studying DNA-Guest Molecule Interactions.
J.Am.Chem.Soc., 145, 2023
8EPI
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Engineering Crystals with Tunable Symmetries from 14- or 16-Base-Long DNA Strands
分子名称: DNA (5'-D(*CP*GP*AP*CP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*A)-3'), DNA (5'-D(P*TP*CP*CP*TP*A)-3')
著者Zhang, C, Zhao, J, Lu, B, Sha, R, Seeman, N.C, Noinaj, N, Mao, C.
登録日2022-10-05
公開日2023-03-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Engineering DNA Crystals toward Studying DNA-Guest Molecule Interactions.
J.Am.Chem.Soc., 145, 2023
8EPF
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Engineering Crystals with Tunable Symmetries from 14- or 16-Base-Long DNA Strands
分子名称: DNA (5'-D(*AP*CP*GP*CP*TP*GP*GP*TP*GP*GP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*GP*TP*AP*CP*CP*AP*GP*CP*CP*GP*AP*AP*CP*CP*TP*G)-3')
著者Zhang, C, Zhao, J, Lu, B, Sha, R, Seeman, N.C, Noinaj, N, Mao, C.
登録日2022-10-05
公開日2023-03-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Engineering DNA Crystals toward Studying DNA-Guest Molecule Interactions.
J.Am.Chem.Soc., 145, 2023
8F42
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Engineering Crystals with Tunable Symmetries from 14- or 16-Base-Long DNA Strands
分子名称: 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*TP*TP*AP*AP*GP*GP*AP*AP*TP*TP*CP*GP*C)-3')
著者Zhang, C, Zhao, J, Lu, B, Sha, R, Seeman, N.C, Noinaj, N, Mao, C.
登録日2022-11-10
公開日2023-03-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Engineering DNA Crystals toward Studying DNA-Guest Molecule Interactions.
J.Am.Chem.Soc., 145, 2023
7RIK
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BU of 7rik by Molmil
Magic-Angle-Spinning NMR Structure of Kinesin-1 Motor Domain Assembled with Microtubules
分子名称: Kinesin-1 heavy chain
著者Zhang, C, Guo, C, Russell, R.W, Quinn, C.M, Li, M, Williams, J.C, Gronenborn, A.M, Polenova, T.
登録日2021-07-20
公開日2022-11-23
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Magic-angle-spinning NMR structure of the kinesin-1 motor domain assembled with microtubules reveals the elusive neck linker orientation
Nat Commun, 13, 2022
7BTA
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BU of 7bta by Molmil
Crystal structure of Rheb D60K mutant bound to GDP
分子名称: GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION
著者Zhang, C, Zhang, T, Ding, J.
登録日2020-03-31
公開日2020-06-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular basis for the functions of dominantly active Y35N and inactive D60K Rheb mutants in mTORC1 signaling.
J Mol Cell Biol, 12, 2020
7BTC
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BU of 7btc by Molmil
Crystal structure of Rheb Y35N mutant bound to GDP
分子名称: GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE
著者Zhang, C, Zhang, T, Ding, J.
登録日2020-04-01
公開日2020-06-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Molecular basis for the functions of dominantly active Y35N and inactive D60K Rheb mutants in mTORC1 signaling.
J Mol Cell Biol, 12, 2020
7BTD
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Crystal structure of Rheb Y35N mutant bound to GppNHp
分子名称: GTP-binding protein Rheb, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Zhang, C, Zhang, T, Ding, J.
登録日2020-04-01
公開日2020-06-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis for the functions of dominantly active Y35N and inactive D60K Rheb mutants in mTORC1 signaling.
J Mol Cell Biol, 12, 2020
6E9F
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EsCas13d-crRNA-target RNA ternary complex
分子名称: EsCas13d, MAGNESIUM ION, RNA (27-MER), ...
著者Zhang, C, Lyumkis, D.
登録日2018-08-01
公開日2018-10-03
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d.
Cell, 175, 2018
6E9E
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EsCas13d-crRNA binary complex
分子名称: EsCas13d, MAGNESIUM ION, crRNA (52-MER)
著者Zhang, C, Lyumkis, D.
登録日2018-08-01
公開日2018-10-03
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d.
Cell, 175, 2018
2DHO
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BU of 2dho by Molmil
Crystal structure of human IPP isomerase I in space group P212121
分子名称: CHLORIDE ION, Isopentenyl-diphosphate delta-isomerase 1, MANGANESE (II) ION, ...
著者Zhang, C, Wei, Z, Gong, W.
登録日2006-03-24
公開日2007-06-05
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of human IPP isomerase: new insights into the catalytic mechanism
J.Mol.Biol., 366, 2007
7BWQ
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Structure of nonstructural protein Nsp9 from SARS-CoV-2
分子名称: Nsp9, SULFATE ION
著者Zhang, C, Chen, Y, Li, L, Su, D.
登録日2020-04-15
公開日2021-07-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.954 Å)
主引用文献Structural basis for the multimerization of nonstructural protein nsp9 from SARS-CoV-2.
Mol Biomed, 1, 2020
3VW7
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Crystal structure of human protease-activated receptor 1 (PAR1) bound with antagonist vorapaxar at 2.2 angstrom
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, Proteinase-activated receptor 1, ...
著者Zhang, C, Srinivasan, Y, Arlow, D.H, Fung, J.J, Palmer, D, Zheng, Y, Green, H.F, Pandey, A, Dror, R.O, Shaw, D.E, Weis, W.I, Coughlin, S.R, Kobilka, B.K.
登録日2012-08-07
公開日2012-12-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献High-resolution crystal structure of human protease-activated receptor 1
Nature, 492, 2012
5ICA
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BU of 5ica by Molmil
Structure of the CTD complex of UTP12, Utp13, Utp1 and Utp21
分子名称: Periodic tryptophan protein 2-like protein, Putative U3 snoRNP protein, Putative uncharacterized protein
著者Zhang, C, Ye, K.
登録日2016-02-23
公開日2016-07-06
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.507 Å)
主引用文献Integrative structural analysis of the UTPB complex, an early assembly factor for eukaryotic small ribosomal subunits
Nucleic Acids Res., 44, 2016
8GH5
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BU of 8gh5 by Molmil
Implementing Logic Gates in DNA Crystal Engineering
分子名称: DNA (5'-D(*AP*GP*AP*CP*G)-3'), DNA (5'-D(*CP*TP*AP*CP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*A)-3'), ...
著者Zhang, C, Paluzzi, V.E, Sha, R, Jonoska, N, Mao, C.
登録日2023-03-09
公開日2023-06-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Implementing Logic Gates by DNA Crystal Engineering.
Adv Mater, 35, 2023
5BOA
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BU of 5boa by Molmil
Crystal Structure of the Meningitis Pathogen Streptococcus suis adhesion Fhb bound to the disaccharide receptor Gb2
分子名称: Translation initiation factor 2 (IF-2 GTPase), alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose
著者Zhang, C, Yu, Y, Yang, M, Jiang, Y.
登録日2015-05-27
公開日2016-05-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.708 Å)
主引用文献Structural basis of the interaction between the meningitis pathogen Streptococcus suis adhesin Fhb and its human receptor.
Febs Lett., 590, 2016
7WL4
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Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor SLP-50
分子名称: Bromodomain-containing protein 4, ~{N}-[2-ethyl-6-(4-methylpiperazin-1-yl)-3-oxidanylidene-2,7-diazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),4,6,8,10-pentaen-9-yl]-2,4-bis(fluoranyl)benzenesulfonamide
著者Zhang, C, Wang, C, Li, W, Zhang, Y, Xu, Y, Sun, L.
登録日2022-01-12
公開日2022-08-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Design, synthesis, and anticancer evaluation of ammosamide B with pyrroloquinoline derivatives as novel BRD4 inhibitors.
Bioorg.Chem., 127, 2022
7BYY
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Crystal structure of bacterial toxin
分子名称: Acetyltransferase
著者Zhang, C, Yashiro, Y, Tomita, K.
登録日2020-04-25
公開日2020-06-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.799 Å)
主引用文献Substrate specificities of Escherichia coli ItaT that acetylates aminoacyl-tRNAs.
Nucleic Acids Res., 48, 2020

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件を2024-05-15に公開中

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