1KQ3
| CRYSTAL STRUCTURE OF A GLYCEROL DEHYDROGENASE (TM0423) FROM THERMOTOGA MARITIMA AT 1.5 A RESOLUTION | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ZINC ION, ... | 著者 | Wilson, I.A, Miller, M.D, Joint Center for Structural Genomics (JCSG) | 登録日 | 2002-01-03 | 公開日 | 2002-02-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline Proc.Natl.Acad.Sci.USA, 99, 2002
|
|
1KQ4
| |
5D9Q
| Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122 and scFv NIH45-46 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | 著者 | Julien, J.-P, Stanfield, R.L, Ward, A.B, Wilson, I.A. | 登録日 | 2015-08-18 | 公開日 | 2016-08-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (4.4 Å) | 主引用文献 | Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design. Plos Pathog., 12, 2016
|
|
2VAA
| |
7T1V
| |
8D53
| |
4I78
| |
6W05
| |
6W00
| Crystal structure of Fab239 in complex with NPNA2 peptide from circumsporozoite protein | 分子名称: | Fab239 heavy chain, Fab239 light chain, Immunoglobulin G-binding protein G, ... | 著者 | Pholcharee, T, Oyen, D, Wilson, I.A. | 登録日 | 2020-02-28 | 公開日 | 2020-07-29 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.853 Å) | 主引用文献 | Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum. Nat Commun, 12, 2021
|
|
6WG1
| |
1A3L
| |
1THZ
| Crystal Structure of Avian AICAR Transformylase in Complex with a Novel Inhibitor Identified by Virtual Ligand Screening | 分子名称: | 2-{(E)-[5-HYDROXY-3-METHYL-1-(2-METHYL-4-SULFOPHENYL)-1H-PYRAZOL-4-YL]DIAZENYL}-4-SULFOBENZOIC ACID, Bifunctional purine biosynthesis protein PURH, POTASSIUM ION | 著者 | Xu, L, Li, C, Olson, A.J, Wilson, I.A. | 登録日 | 2004-06-01 | 公開日 | 2004-09-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of avian aminoimidazole-4-carboxamide ribonucleotide transformylase in complex with a novel non-folate inhibitor identified by virtual ligand screening. J.Biol.Chem., 279, 2004
|
|
6W41
| Crystal structure of SARS-CoV-2 receptor binding domain in complex with human antibody CR3022 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CR3022 Fab heavy chain, CR3022 Fab light chain, ... | 著者 | Yuan, M, Wu, N.C, Zhu, X.Y, Wilson, I.A. | 登録日 | 2020-03-09 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.084 Å) | 主引用文献 | A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV. Science, 368, 2020
|
|
2I26
| |
2I25
| |
3ESP
| Human transthyretin (TTR) complexed with N-(3,5-Dibromo-4-hydroxyphenyl)-3,5-dimethyl-4-hydroxybenzamide | 分子名称: | N-(3,5-dibromo-4-hydroxyphenyl)-4-hydroxy-3,5-dimethylbenzamide, Transthyretin | 著者 | Connelly, S, Wilson, I.A. | 登録日 | 2008-10-06 | 公開日 | 2009-04-07 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | 主引用文献 | Toward optimization of the second aryl substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies. J.Med.Chem., 52, 2009
|
|
6CK8
| |
3ESO
| Human transthyretin (TTR) complexed with N-(3,5-Dibromo-4-hydroxyphenyl)-2,5-dichlorobenzamide | 分子名称: | 2,5-dichloro-N-(3,5-dibromo-4-hydroxyphenyl)benzamide, Transthyretin | 著者 | Connelly, S, Wilson, I.A. | 登録日 | 2008-10-06 | 公開日 | 2009-04-07 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | 主引用文献 | Toward optimization of the second aryl substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies. J.Med.Chem., 52, 2009
|
|
3ESN
| Human transthyretin (TTR) complexed with N-(3,5-Dibromo-4-hydroxyphenyl)-2,6-dimethylbenzamide | 分子名称: | N-(3,5-dibromo-4-hydroxyphenyl)-2,6-dimethylbenzamide, Transthyretin | 著者 | Connelly, S, Wilson, I.A. | 登録日 | 2008-10-06 | 公開日 | 2009-04-07 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Toward optimization of the second aryl substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies. J.Med.Chem., 52, 2009
|
|
1JGU
| STRUCTURAL BASIS FOR DISFAVORED ELIMINATION REACTION IN CATALYTIC ANTIBODY 1D4 | 分子名称: | (2-AMINO-3-PHENYL-BICYCLO[2.2.1]HEPT-2-YL)-PHENYL-METHANONE, Antibody Heavy Chain, Antibody Light Chain, ... | 著者 | Larsen, N.A, Heine, A, Crane, L, Cravatt, B.F, Lerner, R.A, Wilson, I.A. | 登録日 | 2001-06-26 | 公開日 | 2001-12-05 | 最終更新日 | 2018-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis for a disfavored elimination reaction in catalytic antibody 1D4. J.Mol.Biol., 314, 2001
|
|
1JGV
| STRUCTURAL BASIS FOR DISFAVORED ELIMINATION REACTION IN CATALYTIC ANTIBODY 1D4 | 分子名称: | Antibody Heavy Chain, Antibody Light Chain | 著者 | Larsen, N.A, Heine, A, Crane, L, Cravatt, B.F, Lerner, R.A, Wilson, I.A. | 登録日 | 2001-06-26 | 公開日 | 2001-12-05 | 最終更新日 | 2018-01-31 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural basis for a disfavored elimination reaction in catalytic antibody 1D4. J.Mol.Biol., 314, 2001
|
|
1JKX
| Unexpected formation of an epoxide-derived multisubstrate adduct inhibitor on the active site of GAR transformylase | 分子名称: | N-[5'-O-PHOSPHONO-RIBOFURANOSYL]-2-[2-HYDROXY-2-[4-[GLUTAMIC ACID]-N-CARBONYLPHENYL]-3-[2-AMINO-4-HYDROXY-QUINAZOLIN-6-YL]-PROPANYLAMINO]-ACETAMIDE, PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE | 著者 | Greasley, S.E, Marsilje, T.H, Cai, H, Baker, S, Benkovic, S.J, Boger, D.L, Wilson, I.A. | 登録日 | 2001-07-13 | 公開日 | 2001-11-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Unexpected formation of an epoxide-derived multisubstrate adduct inhibitor on the active site of GAR transformylase. Biochemistry, 40, 2001
|
|
1JU3
| BACTERIAL COCAINE ESTERASE COMPLEX WITH TRANSITION STATE ANALOG | 分子名称: | PHENYL BORONIC ACID, cocaine esterase | 著者 | Larsen, N.A, Turner, J.M, Stevens, J, Rosser, S.J, Basran, A, Lerner, R.A, Bruce, N.C, Wilson, I.A. | 登録日 | 2001-08-23 | 公開日 | 2001-12-21 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Crystal structure of a bacterial cocaine esterase. Nat.Struct.Biol., 9, 2002
|
|
6PBV
| Crystal structure of Fab668 complex | 分子名称: | 1,2-ETHANEDIOL, Fab668 heavy chain, Fab668 light chain, ... | 著者 | Oyen, D, Wilson, I.A. | 登録日 | 2019-06-14 | 公開日 | 2020-03-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.566 Å) | 主引用文献 | Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein. Plos Pathog., 16, 2020
|
|
6Q1Z
| |