6W00

Crystal structure of Fab239 in complex with NPNA2 peptide from circumsporozoite protein

Summary for 6W00

Entry DOI	10.2210/pdb6w00/pdb
Descriptor	Immunoglobulin G-binding protein G, Fab239 light chain, Fab239 heavy chain, ... (5 entities in total)
Functional Keywords	malaria, sporozoite, circumsporozoite protein, antibody, immune system
Biological source	Streptococcus sp. group G More
Total number of polymer chains	4
Total formula weight	54976.14
Authors	Pholcharee, T.,Oyen, D.,Wilson, I.A. (deposition date: 2020-02-28, release date: 2020-07-29, Last modification date: 2024-04-03)
Primary citation	Pholcharee, T.,Oyen, D.,Flores-Garcia, Y.,Gonzalez-Paez, G.,Han, Z.,Williams, K.L.,Volkmuth, W.,Emerling, D.,Locke, E.,Richter King, C.,Zavala, F.,Wilson, I.A. Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum. Nat Commun, 12:1063-1063, 2021 Cited by PubMed: 33594061 DOI: 10.1038/s41467-021-21221-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.853 Å)

Structure validation