7CTF
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![BU of 7ctf by Molmil](/molmil-images/mine/7ctf) | Human origin recognition complex 1-5 State II | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ... | Authors: | Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N. | Deposit date: | 2020-08-18 | Release date: | 2021-01-06 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structural insight into the assembly and conformational activation of human origin recognition complex. Cell Discov, 6, 2020
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7CTE
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![BU of 7cte by Molmil](/molmil-images/mine/7cte) | Human Origin Recognition Complex, ORC2-5 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 2, Origin recognition complex subunit 3, ... | Authors: | Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N. | Deposit date: | 2020-08-18 | Release date: | 2021-01-06 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural insight into the assembly and conformational activation of human origin recognition complex. Cell Discov, 6, 2020
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7CTG
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![BU of 7ctg by Molmil](/molmil-images/mine/7ctg) | Human Origin Recognition Complex, ORC1-5 State I | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ... | Authors: | Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N. | Deposit date: | 2020-08-18 | Release date: | 2021-01-06 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | Structural insight into the assembly and conformational activation of human origin recognition complex. Cell Discov, 6, 2020
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6KG3
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![BU of 6kg3 by Molmil](/molmil-images/mine/6kg3) | |
7DHF
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![BU of 7dhf by Molmil](/molmil-images/mine/7dhf) | Vibrio vulnificus Wzb in complex with benzylphosphonate | Descriptor: | GLYCEROL, PHOSPHATE ION, Protein-tyrosine-phosphatase | Authors: | Ma, Q, Wang, X. | Deposit date: | 2020-11-14 | Release date: | 2021-01-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.211 Å) | Cite: | Wzb of Vibrio vulnificus represents a new group of low-molecular-weight protein tyrosine phosphatases with a unique insertion in the W-loop. J.Biol.Chem., 296, 2021
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7DHE
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![BU of 7dhe by Molmil](/molmil-images/mine/7dhe) | Vibrio vulnificus Wzb in complex with benzylphosphonate | Descriptor: | Protein-tyrosine-phosphatase, benzylphosphonic acid | Authors: | Ma, Q, Wang, X. | Deposit date: | 2020-11-14 | Release date: | 2021-01-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Wzb of Vibrio vulnificus represents a new group of low-molecular-weight protein tyrosine phosphatases with a unique insertion in the W-loop. J.Biol.Chem., 296, 2021
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7D5Z
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![BU of 7d5z by Molmil](/molmil-images/mine/7d5z) | Crystal structure of EBV gH/gL bound with neutralizing antibody 1D8 | Descriptor: | Envelope glycoprotein H, Envelope glycoprotein L, heavy chain of 1D8, ... | Authors: | Zhu, Q, Shan, S, Yu, J, Wang, X, Zhang, L, Zeng, M. | Deposit date: | 2020-09-28 | Release date: | 2021-10-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | A Neutralizing Antibody Targeting a New Site of Vulnerability on Epstein-Barr Virus gH/gL Protects against Dual-Tropic Infection To Be Published
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7DHD
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![BU of 7dhd by Molmil](/molmil-images/mine/7dhd) | Vibrio vulnificus Wzb | Descriptor: | CHLORIDE ION, Protein-tyrosine-phosphatase | Authors: | Ma, Q, Wang, X. | Deposit date: | 2020-11-14 | Release date: | 2021-01-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Wzb of Vibrio vulnificus represents a new group of low-molecular-weight protein tyrosine phosphatases with a unique insertion in the W-loop. J.Biol.Chem., 296, 2021
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6LTH
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![BU of 6lth by Molmil](/molmil-images/mine/6lth) | Structure of human BAF Base module | Descriptor: | AT-rich interactive domain-containing protein 1A, SWI/SNF complex subunit SMARCC2, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, ... | Authors: | He, S, Wu, Z, Tian, Y, Yu, Z, Yu, J, Wang, X, Li, J, Liu, B, Xu, Y. | Deposit date: | 2020-01-22 | Release date: | 2020-02-12 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of nucleosome-bound human BAF complex. Science, 367, 2020
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7EB2
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![BU of 7eb2 by Molmil](/molmil-images/mine/7eb2) | Cryo-EM structure of human GABA(B) receptor-Gi protein complex | Descriptor: | (3S)-5,7-ditert-butyl-3-oxidanyl-3-(trifluoromethyl)-1-benzofuran-2-one, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, ... | Authors: | Shen, C, Mao, C, Xu, C, Jin, N, Zhang, H, Shen, D, Shen, Q, Wang, X, Hou, T, Rondard, P, Chen, Z, Pin, J, Zhang, Y, Liu, J. | Deposit date: | 2021-03-08 | Release date: | 2021-05-05 | Last modified: | 2021-07-07 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of GABA B receptor-G i protein coupling. Nature, 594, 2021
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6J11
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![BU of 6j11 by Molmil](/molmil-images/mine/6j11) | MERS-CoV spike N-terminal domain and 7D10 scFv complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-terminal domain of Spike glycoprotein, ... | Authors: | Zhou, H, Zhang, S, Zhang, S, Tang, W, Wang, X. | Deposit date: | 2018-12-27 | Release date: | 2019-07-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein. Nat Commun, 10, 2019
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6LTJ
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![BU of 6ltj by Molmil](/molmil-images/mine/6ltj) | Structure of nucleosome-bound human BAF complex | Descriptor: | AT-rich interactive domain-containing protein 1A, Actin, cytoplasmic 1, ... | Authors: | He, S, Wu, Z, Tian, Y, Yu, Z, Yu, J, Wang, X, Li, J, Liu, B, Xu, Y. | Deposit date: | 2020-01-22 | Release date: | 2020-02-12 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of nucleosome-bound human BAF complex. Science, 367, 2020
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6MEP
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![BU of 6mep by Molmil](/molmil-images/mine/6mep) | Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC3437 | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Tyrosine-protein kinase Mer, ... | Authors: | Da, C, Zhang, D, Stashko, M.A, Cheng, A, Hunter, D, Norris-Drouin, J, Graves, L, Machius, M, Miley, M.J, DeRyckere, D, Earp, H.S, Graham, D.K, Frye, S.V, Wang, X, Kireev, D. | Deposit date: | 2018-09-06 | Release date: | 2019-09-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.893 Å) | Cite: | Data-Driven Construction of Antitumor Agents with Controlled Polypharmacology. J.Am.Chem.Soc., 141, 2019
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7E3N
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![BU of 7e3n by Molmil](/molmil-images/mine/7e3n) | Crystal structure of Isocitrate dehydrogenase D252N mutant from Trypanosoma brucei in complexed with NADP+, alpha-ketoglutarate, and ca2+ | Descriptor: | CALCIUM ION, ISOCITRIC ACID, Isocitrate dehydrogenase [NADP], ... | Authors: | Arai, N, Shiba, T, Inaoka, D.K, Kita, K, Wang, X, Otani, M, Matsushiro, S, Kojima, C. | Deposit date: | 2021-02-09 | Release date: | 2022-02-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of Isocitrate dehydrogenase from Trypanosoma brucei. To Be Published
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6KH2
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![BU of 6kh2 by Molmil](/molmil-images/mine/6kh2) | |
7VRW
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![BU of 7vrw by Molmil](/molmil-images/mine/7vrw) | VAS5 Spike (3 RBD down) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Zhen, C, Wang, X. | Deposit date: | 2021-10-25 | Release date: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | VAS5 Spike (3-RBD down) To Be Published
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7XD9
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![BU of 7xd9 by Molmil](/molmil-images/mine/7xd9) | Crystal Structure of Dengue Virus serotype 2 (DENV2) Polymerase Elongation Complex (CTP Form) | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Wu, J, Wang, X, Gong, P. | Deposit date: | 2022-03-26 | Release date: | 2022-12-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Structural basis of transition from initiation to elongation in de novo viral RNA-dependent RNA polymerases. Proc.Natl.Acad.Sci.USA, 120, 2023
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7XD8
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![BU of 7xd8 by Molmil](/molmil-images/mine/7xd8) | Crystal Structure of Dengue Virus Serotype 2 (DENV2) Polymerase Elongation Complex (Native Form) | Descriptor: | GLYCEROL, NS5, RNA (30-mer), ... | Authors: | Wu, J, Wang, X, Gong, P. | Deposit date: | 2022-03-26 | Release date: | 2022-12-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural basis of transition from initiation to elongation in de novo viral RNA-dependent RNA polymerases. Proc.Natl.Acad.Sci.USA, 120, 2023
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7VYV
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![BU of 7vyv by Molmil](/molmil-images/mine/7vyv) | Cryo-EM structure of Depo32, a Klebsiella phage depolymerase targets the K2 serotype K. pneumoniae | Descriptor: | Depolymerase | Authors: | Cai, R, Ren, Z, Zhao, R, Wang, X, Guo, Z, Du, R, Han, W, Ru, H, Gu, J. | Deposit date: | 2021-11-15 | Release date: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (2.32 Å) | Cite: | Depo32, a depolymerase of Klebsiella phage, efficiently controls infection caused by Klebsiella pneumoniae with K2 serotype CPS To Be Published
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7VZ3
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![BU of 7vz3 by Molmil](/molmil-images/mine/7vz3) | Cryo-EM structure of Depo32, a Klebsiella phage depolymerase targets the K2 serotype K. pneumoniae | Descriptor: | Depolymerase | Authors: | Cai, R, Ren, Z, Zhao, R, Wang, X, Guo, Z, Du, R, Han, W, Ru, H, Gu, J. | Deposit date: | 2021-11-15 | Release date: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (2.46 Å) | Cite: | Depo32, a depolymerase of Klebsiella phage, efficiently controls infection caused by Klebsiella pneumoniae with K2 serotype CPS To Be Published
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2K1H
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![BU of 2k1h by Molmil](/molmil-images/mine/2k1h) | Solution NMR structure of SeR13 from Staphylococcus epidermidis. Northeast Structural Genomics Consortium target SeR13 | Descriptor: | Uncharacterized protein SeR13 | Authors: | Lee, H, Wylie, G, Bansal, S, Wang, X, Shastry, R, Jiang, M, Cunningham, K, Ma, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Prestegard, J.H, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-03-05 | Release date: | 2008-03-18 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Solution Structure of SeR13. To be Published
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5X45
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![BU of 5x45 by Molmil](/molmil-images/mine/5x45) | Crystal structure of 2A protease from Human rhinovirus C15 | Descriptor: | ZINC ION, protease 2A | Authors: | Ling, H, Yang, P, Shaw, N, Sun, Y, Wang, X. | Deposit date: | 2017-02-10 | Release date: | 2018-02-21 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.602 Å) | Cite: | Structural view of the 2A protease from human rhinovirus C15. Acta Crystallogr.,Sect.F, 74, 2018
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7XGL
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![BU of 7xgl by Molmil](/molmil-images/mine/7xgl) | Quinolinate Phosphoribosyl Transferase (QAPRTase) from Streptomyces pyridomyceticus NRRL B-2517 in Apo form | Descriptor: | CHLORIDE ION, GLYCEROL, Quinolinate Phosphoribosyl Transferase, ... | Authors: | Zhou, Z, Yang, X, Huang, T, Wang, X, Liang, R, Zheng, J, Dai, S, Lin, S, Deng, Z. | Deposit date: | 2022-04-05 | Release date: | 2023-03-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Bifunctional NadC Homologue PyrZ Catalyzes Nicotinic Acid Formation in Pyridomycin Biosynthesis. Acs Chem.Biol., 18, 2023
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7XGN
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![BU of 7xgn by Molmil](/molmil-images/mine/7xgn) | Quinolinate Phosphoribosyl Transferase (QAPRTase) from Streptomyces pyridomyceticus NRRL B-2517 in complex with Nicotinic Acid (NA) | Descriptor: | CHLORIDE ION, NICOTINIC ACID, Quinolinate Phosphoribosyl Transferase, ... | Authors: | Zhou, Z, Yang, X, Huang, T, Wang, X, Liang, R, Zheng, J, Dai, S, Lin, S, Deng, Z. | Deposit date: | 2022-04-05 | Release date: | 2023-03-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Bifunctional NadC Homologue PyrZ Catalyzes Nicotinic Acid Formation in Pyridomycin Biosynthesis. Acs Chem.Biol., 18, 2023
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7XGM
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![BU of 7xgm by Molmil](/molmil-images/mine/7xgm) | Quinolinate Phosphoribosyl Transferase (QAPRTase) from Streptomyces pyridomyceticus NRRL B-2517 in complex with Quinolinic Acid (QA) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, QUINOLINIC ACID, ... | Authors: | Zhou, Z, Yang, X, Huang, T, Wang, X, Liang, R, Zheng, J, Dai, S, Lin, S, Deng, Z. | Deposit date: | 2022-04-05 | Release date: | 2023-03-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Bifunctional NadC Homologue PyrZ Catalyzes Nicotinic Acid Formation in Pyridomycin Biosynthesis. Acs Chem.Biol., 18, 2023
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