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7E3N

Crystal structure of Isocitrate dehydrogenase D252N mutant from Trypanosoma brucei in complexed with NADP+, alpha-ketoglutarate, and ca2+

Summary for 7E3N
Entry DOI10.2210/pdb7e3n/pdb
DescriptorIsocitrate dehydrogenase [NADP], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CALCIUM ION, ... (5 entities in total)
Functional Keywordstrypanosoma brucei, glycosome, metabolism, isocitrate dehydrogenase, oxidoreductase
Biological sourceTrypanosoma brucei brucei (strain 927/4 GUTat10.1)
Total number of polymer chains1
Total formula weight47766.21
Authors
Arai, N.,Shiba, T.,Inaoka, D.K.,Kita, K.,Wang, X.,Otani, M.,Matsushiro, S.,Kojima, C. (deposition date: 2021-02-09, release date: 2022-02-16, Last modification date: 2023-11-29)
Primary citationArai, N.,Shiba, T.,Inaoka, D.K.,Kita, K.,Wang, X.,Otani, M.,Matsushiro, S.,Kojima, C.
Crystal structure of Isocitrate dehydrogenase from Trypanosoma brucei.
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

218853

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