Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 149 results

1BXL
DownloadVisualize
BU of 1bxl by Molmil
STRUCTURE OF BCL-XL/BAK PEPTIDE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: BAK PEPTIDE, BCL-XL
Authors:Sattler, M, Liang, H, Nettesheim, D, Meadows, R.P, Harlan, J.E, Eberstadt, M, Yoon, H, Shuker, S.B, Chang, B.S, Minn, A.J, Thompson, C.B, Fesik, S.W.
Deposit date:1996-10-16
Release date:1997-10-29
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis.
Science, 275, 1997
2MJN
DownloadVisualize
BU of 2mjn by Molmil
Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1
Descriptor: Nucleolysin TIA-1 isoform p40
Authors:Sattler, M, Wang, I.
Deposit date:2014-01-13
Release date:2014-04-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1.
Nucleic Acids Res., 42, 2014
8B8S
DownloadVisualize
BU of 8b8s by Molmil
Solution structure of tandem RRM1 and RRM2 domains of yeast NPL3
Descriptor: Serine/arginine (SR)-type shuttling mRNA binding protein NPL3
Authors:Kachariya, N, Sattler, M, Keil, P, Strasser, K.
Deposit date:2022-10-04
Release date:2022-11-09
Last modified:2024-06-19
Method:SOLUTION NMR, SOLUTION SCATTERING
Cite:Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Nucleic Acids Res., 51, 2023
6DCL
DownloadVisualize
BU of 6dcl by Molmil
Crystal structure of UP1 bound to pri-miRNA-18a terminal loop
Descriptor: 1,2-ETHANEDIOL, Heterogeneous nuclear ribonucleoprotein A1, RNA (5'-R(*AP*GP*UP*AP*GP*AP*UP*UP*AP*GP*C)-3')
Authors:Kooshapur, H, Sattler, M.
Deposit date:2018-05-07
Release date:2018-06-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1.
Nat Commun, 9, 2018
4EL6
DownloadVisualize
BU of 4el6 by Molmil
Crystal structure of IPSE/alpha-1 from Schistosoma mansoni eggs
Descriptor: IL-4-inducing protein
Authors:Mayerhofer, H, Meyer, H, Tripsianes, K, Barths, D, Blindow, S, Bade, S, Madl, T, Frey, A, Haas, H, Sattler, M, Schramm, G, Mueller-Dieckmann, J.
Deposit date:2012-04-10
Release date:2013-04-10
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Structure and functional analysis of IPSE/alpha-1, an IL-4-inducing factor secreted from Schistosoma mansoni eggs, reveals an IgE-binding crystallin fold
To be Published
6TR0
DownloadVisualize
BU of 6tr0 by Molmil
Solution structure of U2AF2 RRM1,2
Descriptor: Splicing factor U2AF 65 kDa subunit
Authors:Kang, H.-S, Sattler, M.
Deposit date:2019-12-17
Release date:2020-05-06
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2.
Proc.Natl.Acad.Sci.USA, 117, 2020
8POI
DownloadVisualize
BU of 8poi by Molmil
Molecular Docking of SPF30 Tudor domain with synthetic inhibitor 4-(pyridin-2-yl)thiazol-2-amine
Descriptor: 4-pyridin-2-yl-1,3-thiazol-2-amine, Survival of motor neuron-related-splicing factor 30
Authors:Borggraefe, J, Gaussmann, S, Sattler, M.
Deposit date:2023-07-04
Release date:2023-08-23
Last modified:2023-08-30
Method:SOLUTION NMR
Cite:Pharmacological perturbation of the phase-separating protein SMNDC1.
Nat Commun, 14, 2023
1FHO
DownloadVisualize
BU of 1fho by Molmil
Solution Structure of the PH Domain from the C. Elegans Muscle Protein UNC-89
Descriptor: UNC-89
Authors:Blomberg, N, Baraldi, E, Sattler, M, Saraste, M, Nilges, M.
Deposit date:2000-08-02
Release date:2000-10-04
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of a PH domain from the C. elegans muscle protein UNC-89 suggests a novel function.
Structure Fold.Des., 8, 2000
3DXB
DownloadVisualize
BU of 3dxb by Molmil
Structure of the UHM domain of Puf60 fused to thioredoxin
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, thioredoxin N-terminally fused to Puf60(UHM)
Authors:Corsini, L, Hothorn, M, Scheffzek, K, Stier, G, Sattler, M.
Deposit date:2008-07-24
Release date:2008-10-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Dimerization and Protein Binding Specificity of the U2AF Homology Motif of the Splicing Factor Puf60.
J.Biol.Chem., 284, 2009
8P25
DownloadVisualize
BU of 8p25 by Molmil
Solution structure of a chimeric U2AF2 RRM2 / FUBP1 N-Box
Descriptor: Splicing factor U2AF 65 kDa subunit,Far upstream element-binding protein 1
Authors:Hipp, C, Sattler, M.
Deposit date:2023-05-14
Release date:2023-07-26
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:FUBP1 is a general splicing factor facilitating 3' splice site recognition and splicing of long introns.
Mol.Cell, 83, 2023
8PXX
DownloadVisualize
BU of 8pxx by Molmil
Structure of the WW domain tandem of PRPF40A in complex with SF1
Descriptor: Pre-mRNA-processing factor 40 homolog A, Splicing factor 1
Authors:Martinez-Lumbreras, S, Sattler, M.
Deposit date:2023-07-24
Release date:2024-04-03
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Intramolecular autoinhibition regulates the selectivity of PRPF40A tandem WW domains for proline-rich motifs.
Nat Commun, 15, 2024
8PXW
DownloadVisualize
BU of 8pxw by Molmil
Structure of the WW domain tandem of PRPF40A
Descriptor: Pre-mRNA-processing factor 40 homolog A
Authors:Martinez-Lumbreras, S, Sattler, M.
Deposit date:2023-07-24
Release date:2024-04-03
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Intramolecular autoinhibition regulates the selectivity of PRPF40A tandem WW domains for proline-rich motifs.
Nat Commun, 15, 2024
2JW6
DownloadVisualize
BU of 2jw6 by Molmil
Solution structure of the DEAF1 MYND domain
Descriptor: Deformed epidermal autoregulatory factor 1 homolog, ZINC ION
Authors:Spadaccini, R, Perrin, H, Bottomley, M, Ansieu, S, Sattler, M.
Deposit date:2007-10-08
Release date:2007-12-25
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Retraction notice to "Structure and functional analysis of the MYND domain" [J. Mol. Biol. (2006) 358, 498-508].
J.Mol.Biol., 376, 2008
1D8B
DownloadVisualize
BU of 1d8b by Molmil
NMR STRUCTURE OF THE HRDC DOMAIN FROM SACCHAROMYCES CEREVISIAE RECQ HELICASE
Descriptor: SGS1 RECQ HELICASE
Authors:Liu, Z, Macias, M.J, Bottomley, M.J, Stier, G, Linge, J.P, Nilges, M, Bork, P, Sattler, M.
Deposit date:1999-10-21
Release date:2000-01-10
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The three-dimensional structure of the HRDC domain and implications for the Werner and Bloom syndrome proteins.
Structure Fold.Des., 7, 1999
5L87
DownloadVisualize
BU of 5l87 by Molmil
Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases.
Descriptor: 1,2-ETHANEDIOL, 5-(1~{H}-indol-3-ylmethyl)-1-methyl-~{N}-(naphthalen-1-ylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide, Peroxin 14
Authors:Dawidowski, M, Emmanouilidis, L, Sattler, M, Popowicz, G.M.
Deposit date:2016-06-07
Release date:2017-03-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (0.87 Å)
Cite:Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites.
Science, 355, 2017
2JXC
DownloadVisualize
BU of 2jxc by Molmil
Structure of the EPS15-EH2 Stonin2 Complex
Descriptor: CALCIUM ION, Epidermal growth factor receptor substrate 15, Stonin-2
Authors:Rumpf, J, Simon, B, Jung, N, Maritzen, T, Haucke, V, Sattler, M, Groemping, Y.
Deposit date:2007-11-12
Release date:2008-01-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of the Eps15-stonin2 complex provides a molecular explanation for EH-domain ligand specificity.
Embo J., 27, 2008
5AGQ
DownloadVisualize
BU of 5agq by Molmil
Solution structure of the TAM domain of human TIP5 BAZ2A involved in epigenetic regulation of rRNA genes
Descriptor: BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2A
Authors:Anosova, I, Melnik, S, Tripsianes, K, Kateb, F, Grummt, I, Sattler, M.
Deposit date:2015-02-03
Release date:2015-05-06
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:A Novel RNA Binding Surface of the Tam Domain of Tip5/Baz2A Mediates Epigenetic Regulation of Rrna Genes.
Nucleic Acids Res., 43, 2015
6Y91
DownloadVisualize
BU of 6y91 by Molmil
Crystal structure of malate dehydrogenase from Plasmodium Falciparum in complex with NADH
Descriptor: Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Romero, A.R, Calderone, V, Gentili, M, Lunev, S, Groves, M, Popowicz, G, Domling, A, Sattler, M.
Deposit date:2020-03-06
Release date:2021-03-31
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A fragment-based approach identifies an allosteric pocket that impacts malate dehydrogenase activity.
Commun Biol, 4, 2021
1T2R
DownloadVisualize
BU of 1t2r by Molmil
Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain
Descriptor: 5'-R(*CP*UP*CP*AP*C)-3', Argonaute 2
Authors:Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
Deposit date:2004-04-22
Release date:2004-06-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
1T2S
DownloadVisualize
BU of 1t2s by Molmil
Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain
Descriptor: 5'-D(*CP*TP*CP*AP*C)-3', Argonaute 2
Authors:Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
Deposit date:2004-04-22
Release date:2004-06-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
7Z0J
DownloadVisualize
BU of 7z0j by Molmil
human PEX13 SH3 domain in complex with internal FxxxF motif
Descriptor: 1,2-ETHANEDIOL, Peroxisomal membrane protein PEX13
Authors:Gaussmann, S, Zak, K, Kreisz, N, Sattler, M.
Deposit date:2022-02-23
Release date:2023-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Intramolecular autoinhibition of human PEX13 modulates peroxisomal import
Biorxiv, 2022
7Z0K
DownloadVisualize
BU of 7z0k by Molmil
human PEX13 SH3 in complex with PEX5 W4 (WxxxF/Y) motif
Descriptor: Peroxisomal membrane protein PEX13,Peroxisomal targeting signal 1 receptor
Authors:Gaussmann, S, Napolitano, V, sattler, M.
Deposit date:2022-02-23
Release date:2023-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Intramolecular autoinhibition of human PEX13 modulates peroxisomal import
Biorxiv, 2022
7Z0I
DownloadVisualize
BU of 7z0i by Molmil
human PEX13 SH3 domain
Descriptor: 1,2-ETHANEDIOL, Peroxisomal membrane protein PEX13, ZINC ION
Authors:Gaussmann, S, Zak, K, Sattler, M.
Deposit date:2022-02-23
Release date:2023-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Intramolecular autoinhibition of human PEX13 modulates peroxisomal import
Biorxiv, 2022
1SHC
DownloadVisualize
BU of 1shc by Molmil
SHC PTB DOMAIN COMPLEXED WITH A TRKA RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: SHC, TRKA RECEPTOR PHOSPHOPEPTIDE
Authors:Zhou, M.-M, Ravichandran, K.S, Olejniczak, E.T, Petros, A.M, Meadows, R.P, Sattler, M, Harlan, J.E, Wade, W.S, Burakoff, S.J, Fesik, S.W.
Deposit date:1996-03-27
Release date:1997-05-15
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structure and ligand recognition of the phosphotyrosine binding domain of Shc.
Nature, 378, 1995
7AAF
DownloadVisualize
BU of 7aaf by Molmil
Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor LS2
Descriptor: U2 snRNP auxiliary factor large subunit
Authors:Kawale, A.A, Kang, H.S, Sattler, M.
Deposit date:2020-09-04
Release date:2021-10-06
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor LS2
To Be Published

223166

PDB entries from 2024-07-31

PDB statisticsPDBj update infoContact PDBjnumon