8P25

Solution structure of a chimeric U2AF2 RRM2 / FUBP1 N-Box

Summary for 8P25

• Entry DOI: 10.2210/pdb8p25/pdb
• NMR Information: BMRB: 34816
• Descriptor: Splicing factor U2AF 65 kDa subunit,Far upstream element-binding protein 1 (1 entity in total)
• Functional Keywords: splicing, regulation, protein-protein interaction, rrm
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 1
• Total formula weight: 16296.17

Authors

Hipp, C.,Sattler, M. (deposition date: 2023-05-14, release date: 2023-07-26, Last modification date: 2023-08-16)

• Primary citation: Ebersberger, S.,Hipp, C.,Mulorz, M.M.,Buchbender, A.,Hubrich, D.,Kang, H.S.,Martinez-Lumbreras, S.,Kristofori, P.,Sutandy, F.X.R.,Llacsahuanga Allcca, L.,Schonfeld, J.,Bakisoglu, C.,Busch, A.,Hanel, H.,Tretow, K.,Welzel, M.,Di Liddo, A.,Mockel, M.M.,Zarnack, K.,Ebersberger, I.,Legewie, S.,Luck, K.,Sattler, M.,Konig, J.; FUBP1 is a general splicing factor facilitating 3' splice site recognition and splicing of long introns.; Mol.Cell, 83:2653-, 2023; PubMed: 37506698; DOI: 10.1016/j.molcel.2023.07.002

Experimental method

SOLUTION NMR