5X0X
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![BU of 5x0x by Molmil](/molmil-images/mine/5x0x) | Complex of Snf2-Nucleosome complex with Snf2 bound to position +6 of the nucleosome | 分子名称: | DNA (167-MER), Histone H2A, Histone H2B 1.1, ... | 著者 | Li, M, Liu, X, Xia, X, Chen, Z, Li, X. | 登録日 | 2017-01-23 | 公開日 | 2017-04-19 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.97 Å) | 主引用文献 | Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure. Nature, 544, 2017
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5X0Y
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![BU of 5x0y by Molmil](/molmil-images/mine/5x0y) | Complex of Snf2-Nucleosome complex with Snf2 bound to SHL2 of the nucleosome | 分子名称: | DNA (167-MER), Histone H2A, Histone H2B 1.1, ... | 著者 | Li, M, Liu, X, Xia, X, Chen, Z, Li, X. | 登録日 | 2017-01-23 | 公開日 | 2017-04-19 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.69 Å) | 主引用文献 | Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure. Nature, 544, 2017
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2L8S
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![BU of 2l8s by Molmil](/molmil-images/mine/2l8s) | |
5X4I
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![BU of 5x4i by Molmil](/molmil-images/mine/5x4i) | Pyrococcus furiosus RecJ (D83A, Mn-soaking) | 分子名称: | CHLORIDE ION, MANGANESE (II) ION, Uncharacterized protein | 著者 | Li, M.J, Yi, G.S, Yu, F, Zhou, H, Chen, J.N, Xu, C.Y, Wang, F.P, Xiao, X, He, J.H, Liu, X.P. | 登録日 | 2017-02-13 | 公開日 | 2018-02-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.092 Å) | 主引用文献 | The crystal structure of Pyrococcus furiosus RecJ implicates it as an ancestor of eukaryotic Cdc45. Nucleic Acids Res., 45, 2017
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8HD8
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![BU of 8hd8 by Molmil](/molmil-images/mine/8hd8) | Crystal structure of TMPRSS2 in complex with 212-148 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, CALCIUM ION, ... | 著者 | Wang, H, Liu, X, Sun, L, Yang, H. | 登録日 | 2022-11-03 | 公開日 | 2023-12-13 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry. Nat Commun, 14, 2023
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6JBZ
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![BU of 6jbz by Molmil](/molmil-images/mine/6jbz) | |
5ZCJ
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![BU of 5zcj by Molmil](/molmil-images/mine/5zcj) | Crystal structure of complex | 分子名称: | TP53-binding protein 1, Tudor-interacting repair regulator protein | 著者 | Wang, J, Yuan, Z, Cui, Y, Xie, R, Wang, M, Ma, Y, Yu, X, Liu, X. | 登録日 | 2018-02-17 | 公開日 | 2018-06-27 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.004 Å) | 主引用文献 | Crystal structure of complex To Be Published
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5Z3L
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![BU of 5z3l by Molmil](/molmil-images/mine/5z3l) | Structure of Snf2-nucleosome complex in apo state | 分子名称: | DNA (167-MER), Histone H2A, Histone H2B 1.1, ... | 著者 | Li, M, Xia, X, Liu, X, Li, X, Chen, Z. | 登録日 | 2018-01-08 | 公開日 | 2019-04-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.31 Å) | 主引用文献 | Mechanism of DNA translocation underlying chromatin remodelling by Snf2. Nature, 567, 2019
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5Z3V
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![BU of 5z3v by Molmil](/molmil-images/mine/5z3v) | Structure of Snf2-nucleosome complex at shl-2 in ADP BeFx state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (167-MER), ... | 著者 | Li, M, Xia, X, Liu, X, Li, X, Chen, Z. | 登録日 | 2018-01-08 | 公開日 | 2019-05-22 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.22 Å) | 主引用文献 | Mechanism of DNA translocation underlying chromatin remodelling by Snf2. Nature, 567, 2019
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5Z3O
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![BU of 5z3o by Molmil](/molmil-images/mine/5z3o) | Structure of Snf2-nucleosome complex in ADP state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (167-MER), Histone H2A, ... | 著者 | Li, M, Xia, X, Liu, X, Li, X, Chen, Z. | 登録日 | 2018-01-08 | 公開日 | 2019-04-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | 主引用文献 | Mechanism of DNA translocation underlying chromatin remodelling by Snf2. Nature, 567, 2019
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5ZMU
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![BU of 5zmu by Molmil](/molmil-images/mine/5zmu) | Crystal structure of a cis-epoxysuccinate hydrolase producing D(-)-tartaric acids | 分子名称: | Cis-epoxysuccinate hydrolase, ZINC ION | 著者 | Dong, S, Liu, X, Wang, X, Feng, Y. | 登録日 | 2018-04-06 | 公開日 | 2018-08-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural insight into the catalytic mechanism of a cis-epoxysuccinate hydrolase producing enantiomerically pure d(-)-tartaric acid. Chem. Commun. (Camb.), 54, 2018
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8IOD
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![BU of 8iod by Molmil](/molmil-images/mine/8iod) | Cryo-EM structure of the PG-901-bound human melanocortin receptor 5 (MC5R)-Gs complex | 分子名称: | CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1,HiBiT, ... | 著者 | Feng, W.B, Zhou, Q.T, Chen, X.Y, Dai, A.T, Cai, X.Q, Liu, X, Zhao, F.H, Chen, Y, Ye, C.Y, Xu, Y.N, Cong, Z.T, Li, H, Lin, S, Yang, D.H, Wang, M.W. | 登録日 | 2023-03-10 | 公開日 | 2023-09-20 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | 主引用文献 | Structural insights into ligand recognition and subtype selectivity of the human melanocortin-3 and melanocortin-5 receptors. Cell Discov, 9, 2023
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8INR
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![BU of 8inr by Molmil](/molmil-images/mine/8inr) | Cryo-EM structure of the alpha-MSH-bound human melanocortin receptor 5 (MC5R)-Gs complex | 分子名称: | CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1,HiBiT, ... | 著者 | Feng, W.B, Zhou, Q.T, Chen, X.Y, Dai, A.T, Cai, X.Q, Liu, X, Zhao, F.H, Chen, Y, Ye, C.Y, Xu, Y.N, Cong, Z.T, Li, H, Lin, S, Yang, D.H, Wang, M.W. | 登録日 | 2023-03-10 | 公開日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | 主引用文献 | Structural insights into ligand recognition and subtype selectivity of the human melanocortin-3 and melanocortin-5 receptors. Cell Discov, 9, 2023
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8IOC
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![BU of 8ioc by Molmil](/molmil-images/mine/8ioc) | Cryo-EM structure of the gamma-MSH-bound human melanocortin receptor 3 (MC3R)-Gs complex | 分子名称: | CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1,HiBiT, ... | 著者 | Feng, W.B, Zhou, Q.T, Chen, X.Y, Dai, A.T, Cai, X.Q, Liu, X, Zhao, F.H, Chen, Y, Ye, C.Y, Xu, Y.N, Cong, Z.T, Li, H, Lin, S. | 登録日 | 2023-03-10 | 公開日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Structural insights into ligand recognition and subtype selectivity of the human melanocortin-3 and melanocortin-5 receptors. Cell Discov, 9, 2023
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5WH1
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![BU of 5wh1 by Molmil](/molmil-images/mine/5wh1) | |
5Z3U
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![BU of 5z3u by Molmil](/molmil-images/mine/5z3u) | Structure of Snf2-nucleosome complex at shl2 in ADP BeFx state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (167-MER), ... | 著者 | Li, M, Xia, X, Liu, X, Li, X, Chen, Z. | 登録日 | 2018-01-08 | 公開日 | 2019-05-22 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.31 Å) | 主引用文献 | Mechanism of DNA translocation underlying chromatin remodelling by Snf2. Nature, 567, 2019
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5X4J
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![BU of 5x4j by Molmil](/molmil-images/mine/5x4j) | The crystal structure of Pyrococcus furiosus RecJ (Zn-soaking) | 分子名称: | CHLORIDE ION, Uncharacterized protein, ZINC ION | 著者 | Li, M.J, Yi, G.S, Yu, F, Zhou, H, Chen, J.N, Xu, C.Y, Wang, F.P, Xiao, X, He, J.H, Liu, X.P. | 登録日 | 2017-02-13 | 公開日 | 2018-02-14 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | The crystal structure of Pyrococcus furiosus RecJ implicates it as an ancestor of eukaryotic Cdc45. Nucleic Acids Res., 45, 2017
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5X4K
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![BU of 5x4k by Molmil](/molmil-images/mine/5x4k) | The complex crystal structure of Pyrococcus furiosus RecJ and CMP | 分子名称: | CYTIDINE-5'-MONOPHOSPHATE, Uncharacterized protein, ZINC ION | 著者 | Li, M.J, Yi, G.S, Yu, F, Zhou, H, Chen, J.N, Xu, C.Y, Wang, F.P, Xiao, X, He, J.H, Liu, X.P. | 登録日 | 2017-02-13 | 公開日 | 2018-02-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.749 Å) | 主引用文献 | The crystal structure of Pyrococcus furiosus RecJ implicates it as an ancestor of eukaryotic Cdc45. Nucleic Acids Res., 45, 2017
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5X4H
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![BU of 5x4h by Molmil](/molmil-images/mine/5x4h) | The crystal structure of Pyrococcus furiosus RecJ (wild-type) | 分子名称: | MAGNESIUM ION, Uncharacterized protein | 著者 | Li, M.J, Yi, G.S, Yu, F, Zhou, H, Chen, J.N, Xu, C.Y, Wang, F.P, Xiao, X, He, J.H, Liu, X.P. | 登録日 | 2017-02-13 | 公開日 | 2018-02-14 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | 主引用文献 | The crystal structure of Pyrococcus furiosus RecJ implicates it as an ancestor of eukaryotic Cdc45. Nucleic Acids Res., 45, 2017
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5YH1
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![BU of 5yh1 by Molmil](/molmil-images/mine/5yh1) | |
5WFU
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![BU of 5wfu by Molmil](/molmil-images/mine/5wfu) | |
6KGT
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![BU of 6kgt by Molmil](/molmil-images/mine/6kgt) | Crystal structure of Penicillin binding protein 3 (PBP3) from Mycobacterium tuerculosis, complexed with faropenem | 分子名称: | (2R)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-5-[(2R)-oxolan-2-yl]-2,3-dihydro-1,3-thiazole-4-carboxylic acid, COBALT (II) ION, Penicillin-binding protein PbpB | 著者 | Lu, Z.K, Zhang, A.L, Liu, X, Guddat, L, Yang, H.T, Rao, Z.H. | 登録日 | 2019-07-12 | 公開日 | 2020-03-11 | 実験手法 | X-RAY DIFFRACTION (2.308 Å) | 主引用文献 | Structures ofMycobacterium tuberculosisPenicillin-Binding Protein 3 in Complex with Fivebeta-Lactam Antibiotics Reveal Mechanism of Inactivation. Mol.Pharmacol., 97, 2020
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6KGU
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![BU of 6kgu by Molmil](/molmil-images/mine/6kgu) | Crystal structure of Penicillin binding protein 3 (PBP3) from Mycobacterium tuerculosis, complexed with aztreonam | 分子名称: | 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-oxo-2-{[(2S,3S)-1-oxo-3-(sulfoamino)butan-2-yl]amino}ethylidene]amino}oxy)-2-methylpropanoic acid, COBALT (II) ION, Penicillin-binding protein PbpB | 著者 | Lu, Z.K, Zhang, A.L, Liu, X, Guddat, L, Yang, H.T, Rao, Z.H. | 登録日 | 2019-07-12 | 公開日 | 2020-03-11 | 実験手法 | X-RAY DIFFRACTION (2.106 Å) | 主引用文献 | Structures ofMycobacterium tuberculosisPenicillin-Binding Protein 3 in Complex with Fivebeta-Lactam Antibiotics Reveal Mechanism of Inactivation. Mol.Pharmacol., 97, 2020
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5WFD
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![BU of 5wfd by Molmil](/molmil-images/mine/5wfd) | Humanized mutant of the Chaetomium thermophilum Polycomb Repressive Complex 2 bound to the inhibitor GSK126 | 分子名称: | 1-[(2S)-butan-2-yl]-N-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-3-methyl-6-[6-(piperazin-1-yl)pyridin-3-yl]-1H-indole-4-carboxamide, Histone-lysine-N-methyltransferase EZH2, Polycomb protein SUZ12 chimera, ... | 著者 | Bratkowski, M.A, Liu, X. | 登録日 | 2017-07-11 | 公開日 | 2018-06-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.654 Å) | 主引用文献 | An Evolutionarily Conserved Structural Platform for PRC2 Inhibition by a Class of Ezh2 Inhibitors. Sci Rep, 8, 2018
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5WF7
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![BU of 5wf7 by Molmil](/molmil-images/mine/5wf7) | Chaetomium thermophilum Polycomb Repressive Complex 2 bound to GSK126 | 分子名称: | 1-[(2S)-butan-2-yl]-N-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-3-methyl-6-[6-(piperazin-1-yl)pyridin-3-yl]-1H-indole-4-carboxamide, Histone-lysine-N-methyltransferase EZH2, Polycomb protein SUZ12 chimera, ... | 著者 | Bratkowski, M.A, Liu, X. | 登録日 | 2017-07-11 | 公開日 | 2018-06-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | An Evolutionarily Conserved Structural Platform for PRC2 Inhibition by a Class of Ezh2 Inhibitors. Sci Rep, 8, 2018
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