5KJI
| Crystal structure of an active polycomb repressive complex 2 in the basal state | Descriptor: | Putative uncharacterized protein,Zinc finger domain-containing protein, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... | Authors: | Jiao, L, Liu, X. | Deposit date: | 2016-06-20 | Release date: | 2017-04-19 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Response to Comment on "Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2". Science, 354, 2016
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8B56
| Crystal structure of SARS-CoV-2 main protease (MPro) in complex with the inhibitor GD-9 | Descriptor: | (2~{S})-4-(2-chloranylethanoyl)-1-(3,4-dichlorophenyl)-~{N}-(thiophen-2-ylmethyl)piperazine-2-carboxamide, 3C-like proteinase nsp5, BROMIDE ION, ... | Authors: | Straeter, N, Muller, C.E, Claff, T, Sylvester, K, Weisse, R, Gao, S, Song, L, Liu, X, Zhan, P. | Deposit date: | 2022-09-21 | Release date: | 2023-08-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.823 Å) | Cite: | Discovery and Crystallographic Studies of Nonpeptidic Piperazine Derivatives as Covalent SARS-CoV-2 Main Protease Inhibitors. J.Med.Chem., 65, 2022
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6EG8
| Structure of the GDP-bound Gs heterotrimer | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Hilger, D, Liu, X, Aschauer, P, Kobilka, B.K. | Deposit date: | 2018-08-19 | Release date: | 2019-06-05 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Insights into the Process of GPCR-G Protein Complex Formation. Cell, 177, 2019
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7F05
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5GZO
| Structure of neutralizing antibody bound to Zika envelope protein | Descriptor: | Antibody heavy chain, Antibody light chain, Genome polyprotein | Authors: | Wang, Q, Yang, H, Liu, X, Dai, L, Ma, T, Qi, J, Wong, G, Peng, R, Liu, S, Li, J, Li, S, Song, J, Liu, J, He, J, Yuan, H, Xiong, Y, Liao, Y, Li, J, Yang, J, Tong, Z, Griffin, B, Bi, Y, Liang, M, Xu, X, Cheng, G, Wang, P, Qiu, X, Kobinger, G, Shi, Y, Yan, J, Gao, G.F. | Deposit date: | 2016-09-29 | Release date: | 2017-01-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.755 Å) | Cite: | Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus Sci Transl Med, 8, 2016
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1BIO
| HUMAN COMPLEMENT FACTOR D IN COMPLEX WITH ISATOIC ANHYDRIDE INHIBITOR | Descriptor: | COMPLEMENT FACTOR D, GLYCEROL, ISATOIC ANHYDRIDE | Authors: | Jing, H, Babu, Y.S, Moore, D, Kilpatrick, J.M, Liu, X.-Y, Volanakis, J.E, Narayana, S.V.L. | Deposit date: | 1998-06-18 | Release date: | 1999-06-22 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity. J.Mol.Biol., 282, 1998
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1HFD
| HUMAN COMPLEMENT FACTOR D IN A P21 CRYSTAL FORM | Descriptor: | COMPLEMENT FACTOR D | Authors: | Jing, H, Babu, Y.S, Moore, D, Kilpatrick, J.M, Liu, X.-Y, Volanakis, J.E, Narayana, S.V.L. | Deposit date: | 1998-06-18 | Release date: | 1999-06-22 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity. J.Mol.Biol., 282, 1998
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3JCU
| Cryo-EM structure of spinach PSII-LHCII supercomplex at 3.2 Angstrom resolution | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | Authors: | Wei, X.P, Zhang, X.Z, Su, X.D, Cao, P, Liu, X.Y, Li, M, Chang, W.R, Liu, Z.F. | Deposit date: | 2016-03-10 | Release date: | 2016-05-25 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of spinach photosystem II-LHCII supercomplex at 3.2 A resolution Nature, 534, 2016
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2AIU
| Crystal Structure of Mouse Testicular Cytochrome C at 1.6 Angstrom | Descriptor: | Cytochrome c, testis-specific, PHOSPHATE ION, ... | Authors: | Liu, Z, Ye, S, Lin, H, Rao, Z, Liu, X.J. | Deposit date: | 2005-08-01 | Release date: | 2006-07-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Remarkably high activities of testicular cytochrome c in destroying reactive oxygen species and in triggering apoptosis Proc.Natl.Acad.Sci.Usa, 103, 2006
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5HLH
| Crystal structure of the overoxidized AbfR bound to DNA | Descriptor: | DNA (5'-D(*TP*AP*AP*CP*TP*CP*AP*AP*TP*CP*GP*CP*GP*CP*GP*CP*GP*AP*TP*TP*GP*AP*GP*T)-3'), MarR family transcriptional regulator | Authors: | Liu, G, Liu, X, Gan, J, Yang, C.-G. | Deposit date: | 2016-01-15 | Release date: | 2017-01-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR. J. Am. Chem. Soc., 139, 2017
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3LEH
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5HLI
| Structure of Disulfide formed AbfR | Descriptor: | CHLORIDE ION, COPPER (II) ION, MarR family transcriptional regulator | Authors: | Liu, G, Liu, X, Gan, J, Yang, C.-G. | Deposit date: | 2016-01-15 | Release date: | 2017-01-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR. J. Am. Chem. Soc., 139, 2017
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5HLG
| Structure of reduced AbfR bound to DNA | Descriptor: | DNA (5'-D(*TP*AP*AP*CP*TP*CP*AP*AP*TP*CP*GP*CP*GP*CP*GP*CP*GP*AP*TP*TP*GP*AP*GP*T)-3'), MarR family transcriptional regulator | Authors: | Liu, G, Liu, X, Gan, J, Yang, C.G. | Deposit date: | 2016-01-15 | Release date: | 2017-01-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR. J. Am. Chem. Soc., 139, 2017
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5GWZ
| The structure of Porcine epidemic diarrhea virus main protease in complex with an inhibitor | Descriptor: | N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE, PEDV main protease | Authors: | Wang, F, Chen, C, Yang, K, Liu, X, Liu, H, Xu, Y, Chen, X, Liu, X, Cai, Y, Yang, H. | Deposit date: | 2016-09-14 | Release date: | 2017-03-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.444 Å) | Cite: | Michael Acceptor-Based Peptidomimetic Inhibitor of Main Protease from Porcine Epidemic Diarrhea Virus J. Med. Chem., 60, 2017
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8WYF
| Cryo-EM structure of DSR2-DSAD1-NAD+ (partial) complex | Descriptor: | Bacillus phage SPbeta DSAD1 protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2 family protein | Authors: | Zhang, J.T, Jia, N, Liu, X.Y. | Deposit date: | 2023-10-30 | Release date: | 2024-04-10 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system. Nat Commun, 15, 2024
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8WYC
| Cryo-EM structure of DSR2 (H171A)-tube-NAD+ (partial) complex | Descriptor: | Bacillus phage SPR Tube protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2-like domain-containing protein | Authors: | Zhang, J.T, Jia, N, Liu, X.Y. | Deposit date: | 2023-10-30 | Release date: | 2024-04-10 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system. Nat Commun, 15, 2024
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8WYD
| Cryo-EM structure of DSR2-DSAD1 complex | Descriptor: | Bacillus phage SPbeta DSAD1 protein, SIR2 family protein | Authors: | Zhang, J.T, Jia, N, Liu, X.Y. | Deposit date: | 2023-10-30 | Release date: | 2024-04-10 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.56 Å) | Cite: | Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system. Nat Commun, 15, 2024
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8WYE
| Cryo-EM structure of DSR2-DSAD1 (partial) complex | Descriptor: | Bacillus phage SPbeta DSAD1 protein, SIR2 family protein | Authors: | Zhang, J.T, Jia, N, Liu, X.Y. | Deposit date: | 2023-10-30 | Release date: | 2024-04-10 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.49 Å) | Cite: | Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system. Nat Commun, 15, 2024
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8WY9
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8WYA
| Cryo-EM structure of DSR2-tube complex | Descriptor: | Bacillus phage SPbeta tube protein, SIR2 family protein | Authors: | Zhang, J.T, Jia, N, Liu, X.Y. | Deposit date: | 2023-10-30 | Release date: | 2024-04-10 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (3.62 Å) | Cite: | Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system. Nat Commun, 15, 2024
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8WYB
| Cryo-EM structure of DSR2 (H171A)-tube-NAD+ complex | Descriptor: | Bacillus phage SPR Tube protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2-like domain-containing protein | Authors: | Zhang, J.T, Jia, N, Liu, X.Y. | Deposit date: | 2023-10-30 | Release date: | 2024-04-10 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system. Nat Commun, 15, 2024
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8WY8
| Cryo-EM structure of DSR2 apo complex | Descriptor: | SIR2 family protein | Authors: | Zhang, J.T, Jia, N, Liu, X.Y. | Deposit date: | 2023-10-30 | Release date: | 2024-04-10 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system. Nat Commun, 15, 2024
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1C40
| BAR-HEADED GOOSE HEMOGLOBIN (AQUOMET FORM) | Descriptor: | PROTEIN (HEMOGLOBIN (ALPHA CHAIN)), PROTEIN (HEMOGLOBIN (BETA CHAIN)), PROTOPORPHYRIN IX CONTAINING FE | Authors: | Li, S, Liu, X, Jing, H, Hua, Z, Zhang, R, Lu, G. | Deposit date: | 1999-08-03 | Release date: | 1999-08-09 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Avian haemoglobins and structural basis of high affinity for oxygen: structure of bar-headed goose aquomet haemoglobin. Acta Crystallogr.,Sect.D, 57, 2001
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6IG5
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6IGA
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