8JT3
| Crystal structure of aminotransferase CrmG from Actinoalloteichus sp. WH1-2216-6 in complex with amino donor L-Arg | 分子名称: | (E)-N~2~-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-arginine, ACETATE ION, CrmG, ... | 著者 | Su, K, Zhang, Y, Xu, J, Liu, J. | 登録日 | 2023-06-21 | 公開日 | 2023-08-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Co-crystal structure provides insights on transaminase CrmG recognition amino donor L-Arg. Biochem.Biophys.Res.Commun., 675, 2023
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3Q2C
| Binding properties to HLA class I molecules and the structure of the leukocyte Ig-like receptor A3 (LILRA3/ILT6/LIR4/CD85e) | 分子名称: | Leukocyte immunoglobulin-like receptor subfamily A member 3 | 著者 | Ryu, M, Chen, Y, Qi, J.X, Liu, J, Shi, Y, Cheng, H, Gao, G.F. | 登録日 | 2010-12-20 | 公開日 | 2011-07-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1/LILRB2: structural evidence Plos One, 6, 2011
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5GW0
| Crystal structure of SNX16 PX-Coiled coil | 分子名称: | Sorting nexin-16 | 著者 | Xu, J, Liu, J. | 登録日 | 2016-09-08 | 公開日 | 2017-09-13 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | SNX16 Regulates the Recycling of E-Cadherin through a Unique Mechanism of Coordinated Membrane and Cargo Binding. Structure, 25, 2017
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5GW1
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4RMZ
| Crystal Structure of IRAK-4 | 分子名称: | 3-nitro-N-[1-phenyl-5-(piperidin-1-ylmethyl)-1H-benzimidazol-2-yl]benzamide, Interleukin-1 receptor-associated kinase 4 | 著者 | Johnstone, S, Sudom, A, Liu, J, Walker, N.P, Wang, Z. | 登録日 | 2014-10-22 | 公開日 | 2016-01-13 | 最終更新日 | 2016-03-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of IRAK-4 kinase in complex with inhibitors: a serine/threonine kinase with tyrosine as a gatekeeper To be Published
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3R02
| The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors | 分子名称: | 7-[(cis-4-aminocyclohexyl)amino]-5-bromo-1-benzofuran-2-carboxylic acid, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase pim-1 | 著者 | Xiang, Y, Hirth, B, Asmussen, G, Biemann, H.-P, Good, A, Fitzgerald, M, Gladysheva, T, Jancsics, K, Liu, J, Metz, M, Papoulis, A, Skerlj, R, Stepp, D.J, Wei, R.R. | 登録日 | 2011-03-07 | 公開日 | 2011-05-11 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
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2GTB
| Crystal structure of SARS coronavirus main peptidase (with an additional Ala at the N-terminus of each protomer) inhibited by an aza-peptide epoxide in the space group P43212 | 分子名称: | (5S,8S,14R)-ETHYL 11-(3-AMINO-3-OXOPROPYL)-8-BENZYL-14-HYDROXY-5-ISOBUTYL-3,6,9,12-TETRAOXO-1-PHENYL-2-OXA-4,7,10,11-TETRAAZAPENTADECAN-15-OATE, 3C-like proteinase, ACETIC ACID | 著者 | Lee, T.-W, Cherney, M.M, Huitema, C, Liu, J, James, K.E, Powers, J.C. | 登録日 | 2006-04-27 | 公開日 | 2006-12-26 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures Reveal an Induced-fit Binding of a Substrate-like Aza-peptide Epoxide to SARS Coronavirus Main Peptidase. J.Mol.Biol., 366, 2007
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2B3K
| Crystal structure of Human Methionine Aminopeptidase Type I in the holo form | 分子名称: | ACETATE ION, COBALT (II) ION, GLYCEROL, ... | 著者 | Addlagatta, A, Hu, X, Liu, J.O, Matthews, B.W. | 登録日 | 2005-09-20 | 公開日 | 2005-11-22 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural Basis for the Functional Differences between Type I and Type II Human Methionine Aminopeptidases(,). Biochemistry, 44, 2005
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4UC3
| Translocator protein 18 kDa (TSPO) from Rhodobacter sphaeroides wild type | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, TRANSLOCATOR PROTEIN TSPO | 著者 | Li, F, Liu, J, Zheng, Y, Garavito, R.M, Ferguson-Miller, S. | 登録日 | 2014-08-13 | 公開日 | 2015-02-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism. Science, 347, 2015
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2GT8
| Crystal structure of SARS coronavirus main peptidase (with an additional Ala at the N-terminus of each protomer) in the space group P43212 | 分子名称: | 3C-like proteinase | 著者 | Lee, T.-W, Cherney, M.M, Huitema, C, Liu, J, James, K.E, Powers, J.C, Eltis, L.D, James, M.N.G. | 登録日 | 2006-04-27 | 公開日 | 2006-12-26 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures Reveal an Induced-fit Binding of a Substrate-like Aza-peptide Epoxide to SARS Coronavirus Main Peptidase. J.Mol.Biol., 366, 2007
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5ZG9
| Crystal structure of MoSub1-ssDNA complex in phosphate buffer | 分子名称: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*G)-3'), MoSub1, PHOSPHATE ION | 著者 | Zhao, Y, Huang, J, Liu, H, Yi, L, Wang, S, Zhang, X, Liu, J. | 登録日 | 2018-03-08 | 公開日 | 2019-03-27 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | The effect of phosphate ion on the ssDNA binding mode of MoSub1, a Sub1/PC4 homolog from rice blast fungus. Proteins, 87, 2019
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2QGG
| X-Ray structure of the protein Q6F7I0 from Acinetobacter calcoaceticus AmMS 248. Northeast Structural Genomics Consortium target AsR73. | 分子名称: | 16S rRNA-processing protein rimM, POTASSIUM ION, UNKNOWN LIGAND | 著者 | Kuzin, A.P, Su, M, Jayaraman, S, Wang, D, Janjua, H, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-06-28 | 公開日 | 2007-07-17 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | X-Ray structure of the protein Q6F7I0 from Acinetobacter calcoaceticus AmMS 248. To be Published
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3DNO
| Molecular structure for the HIV-1 gp120 trimer in the CD4-bound state | 分子名称: | HIV-1 envelope glycoprotein gp120 | 著者 | Borgnia, M.J, Liu, J, Bartesaghi, A, Sapiro, G, Subramaniam, S. | 登録日 | 2008-07-02 | 公開日 | 2008-08-19 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (20 Å) | 主引用文献 | Molecular architecture of native HIV-1 gp120 trimers. Nature, 455, 2008
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2HEP
| Solution NMR structure of the UPF0291 protein ynzC from Bacillus subtilis. Northeast Structural Genomics target SR384. | 分子名称: | UPF0291 protein ynzC | 著者 | Aramini, J.M, Swapna, G.V.T, Ho, C.K, Shetty, K, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-06-21 | 公開日 | 2006-08-15 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of the SOS response protein YnzC from Bacillus subtilis Proteins, 72, 2008
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3DNN
| Molecular structure for the HIV-1 gp120 trimer in the unliganded state | 分子名称: | HIV-1 envelope glycoprotein gp120 | 著者 | Borgnia, M.J, Liu, J, Bartesaghi, A, Sapiro, G, Subramaniam, S. | 登録日 | 2008-07-02 | 公開日 | 2008-08-19 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (20 Å) | 主引用文献 | Molecular architecture of native HIV-1 gp120 trimers. Nature, 455, 2008
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2V5M
| Structural basis for Dscam isoform specificity | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DSCAM, GLYCEROL | 著者 | Meijers, R, Puettmann-Holgado, R, Skiniotis, G, Liu, J.-H, Walz, T, Schmucker, D, Wang, J.-H. | 登録日 | 2007-07-06 | 公開日 | 2007-09-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural Basis of Dscam Isoform Specificity Nature, 449, 2007
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2V5S
| Structural basis for Dscam isoform specificity | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DSCAM | 著者 | Meijers, R, Puettmann-Holgado, R, Skiniotis, G, Liu, J.-H, Walz, T, Schmucker, D, Wang, J.-H. | 登録日 | 2007-07-09 | 公開日 | 2007-09-11 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis of Dscam Isoform Specificity Nature, 449, 2007
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2GT7
| Crystal structure of SARS coronavirus main peptidase at pH 6.0 in the space group P21 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3C-like proteinase | 著者 | Lee, T.-W, Cherney, M.M, Huitema, C, Liu, J, James, K.E, Powers, J.C, Eltis, L.D, James, M.N.G. | 登録日 | 2006-04-27 | 公開日 | 2006-12-26 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Crystal Structures Reveal an Induced-fit Binding of a Substrate-like Aza-peptide Epoxide to SARS Coronavirus Main Peptidase. J.Mol.Biol., 366, 2007
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2B3L
| Crystal structure of type I human methionine aminopeptidase in the apo form | 分子名称: | ACETIC ACID, GLYCEROL, Methionine aminopeptidase 1, ... | 著者 | Addlagatta, A, Hu, X, Liu, J.O, Matthews, B.W. | 登録日 | 2005-09-20 | 公開日 | 2005-11-22 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural Basis for the Functional Differences between Type I and Type II Human Methionine Aminopeptidases(,). Biochemistry, 44, 2005
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3R04
| The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors | 分子名称: | 5-{6-[(trans-4-aminocyclohexyl)amino]pyrazin-2-yl}-1-benzofuran-2-carboxylic acid, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase pim-1 | 著者 | Xiang, Y, Hirth, B, Asmussen, G, Biemann, H.-P, Good, A, Fitzgerald, M, Gladysheva, T, Jancsics, K, Liu, J, Metz, M, Papoulis, A, Skerlj, R, Stepp, D.J, Wei, R.R. | 登録日 | 2011-03-07 | 公開日 | 2011-05-11 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
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4FAO
| Specificity and Structure of a high affinity Activin-like 1 (ALK1) signaling complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2B, Growth/differentiation factor 2, ... | 著者 | Townson, S.A, Martinez-Hackert, E, Greppi, C, Lowden, P, Sako, D, Liu, J, Ucran, J.A, Liharska, K, Underwood, K.W, Seehra, J, Kumar, R, Grinberg, A.V. | 登録日 | 2012-05-22 | 公開日 | 2012-06-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.357 Å) | 主引用文献 | Specificity and Structure of a High Affinity Activin Receptor-like Kinase 1 (ALK1) Signaling Complex. J.Biol.Chem., 287, 2012
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3DNL
| Molecular structure for the HIV-1 gp120 trimer in the b12-bound state | 分子名称: | HIV-1 envelope glycoprotein gp120 | 著者 | Borgnia, M.J, Liu, J, Bartesaghi, A, Sapiro, G, Subramaniam, S. | 登録日 | 2008-07-02 | 公開日 | 2008-08-19 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (20 Å) | 主引用文献 | Molecular architecture of native HIV-1 gp120 trimers. Nature, 455, 2008
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3AMQ
| E134C-Cellobiose co-crystal of cellulase 12A from thermotoga maritima | 分子名称: | Endo-1,4-beta-glucanase, beta-D-glucopyranose, beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Cheng, Y.-S, Ko, T.-P, Liu, J.-R, Guo, R.-T. | 登録日 | 2010-08-20 | 公開日 | 2011-03-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure and substrate-binding mode of cellulase 12A from Thermotoga maritima Proteins, 79, 2011
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3RWI
| Rhesus macaque MHC class I molecule Mamu-B*17-GW10 | 分子名称: | Beta-2-microglobulin, Major histocompatibility complex class I, Vif GW10 peptide from Virion infectivity factor | 著者 | Wu, Y, Gao, F, Liu, J, Qi, J.X, Price, D.A, Gao, G.F. | 登録日 | 2011-05-09 | 公開日 | 2012-03-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.009 Å) | 主引用文献 | Structural basis of diverse peptide accommodation by the rhesus macaque MHC class I molecule Mamu-B*17: insights into immune protection from simian immunodeficiency virus J.Immunol., 187, 2011
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3AXE
| The truncated Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase V18Y/W203Y in complex with cellotetraose (cellobiose density was observed) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucanase, CALCIUM ION, ... | 著者 | Huang, J.W, Cheng, Y.S, Ko, T.P, Lin, C.Y, Lai, H.L, Chen, C.C, Ma, Y, Huang, C.H, Zheng, Y, Liu, J.R, Guo, R.T. | 登録日 | 2011-04-04 | 公開日 | 2012-02-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Rational design to improve thermostability and specific activity of the truncated Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase Appl.Microbiol.Biotechnol., 94, 2012
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