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PDB: 73 件

8EAQ
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Structure of the full-length IP3R1 channel determined at high Ca2+
分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, CALCIUM ION, Inositol 1,4,5-trisphosphate receptor type 1, ...
著者Fan, G, Baker, M.R, Terry, L.E, Arige, V, Chen, M, Seryshev, A.B, Baker, M.L, Ludtke, S.J, Yule, D.I, Serysheva, I.I.
登録日2022-08-29
公開日2022-11-23
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Conformational motions and ligand-binding underlying gating and regulation in IP 3 R channel.
Nat Commun, 13, 2022
8EAR
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BU of 8ear by Molmil
Structure of the full-length IP3R1 channel determined in the presence of Calcium/IP3/ATP
分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ...
著者Fan, G, Baker, M.R, Terry, L.E, Arige, V, Chen, M, Seryshev, A.B, Baker, M.L, Ludtke, S.J, Yule, D.I, Serysheva, I.I.
登録日2022-08-29
公開日2022-11-23
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Conformational motions and ligand-binding underlying gating and regulation in IP 3 R channel.
Nat Commun, 13, 2022
3JAV
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BU of 3jav by Molmil
Structure of full-length IP3R1 channel in the apo-state determined by single particle cryo-EM
分子名称: Inositol 1,4,5-trisphosphate receptor type 1
著者Fan, G, Baker, M.L, Wang, Z, Baker, M.R, Sinyagovskiy, P.A, Chiu, W, Ludtke, S.J, Serysheva, I.I.
登録日2015-06-30
公開日2015-10-07
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Gating machinery of InsP3R channels revealed by electron cryomicroscopy.
Nature, 527, 2015
7OAE
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Cryo-EM structure of the plectasin fibril (double strands)
分子名称: Fungal defensin plectasin
著者Effantin, G.
登録日2021-04-19
公開日2022-04-27
最終更新日2022-11-16
実験手法ELECTRON MICROSCOPY (2 Å)
主引用文献pH- and concentration-dependent supramolecular assembly of a fungal defensin plectasin variant into helical non-amyloid fibrils.
Nat Commun, 13, 2022
7OAG
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Cryo-EM structure of the plectasin fibril (single strand)
分子名称: Fungal defensin plectasin
著者Effantin, G.
登録日2021-04-19
公開日2022-04-27
最終更新日2022-11-16
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献pH- and concentration-dependent supramolecular assembly of a fungal defensin plectasin variant into helical non-amyloid fibrils.
Nat Commun, 13, 2022
7OZ4
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BU of 7oz4 by Molmil
Mature capsid of bacteriophage phiRSA1
分子名称: p2 family phage major capsid protein
著者Effantin, G, Fujiwara, A, Kawsaki, T, Yamada, T, Schoehn, G.
登録日2021-06-25
公開日2021-11-17
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献High Resolution Structure of the Mature Capsid of Ralstonia solanacearum Bacteriophage phi RSA1 by Cryo-Electron Microscopy.
Int J Mol Sci, 22, 2021
7K78
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antibody and nucleosome complex
分子名称: Cse4, DNA (136-MER), Histone H2A.1, ...
著者Ruifang, G, Yawen, B.
登録日2020-09-22
公開日2021-03-31
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation.
Nat Commun, 12, 2021
7K7G
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BU of 7k7g by Molmil
nucleosome and Gal4 complex
分子名称: Centromere DNA-binding protein complex CBF3 subunit B, DNA (147-MER), Histone H2A.1, ...
著者Ruifang, G, Yawen, B.
登録日2020-09-22
公開日2021-03-31
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation.
Nat Commun, 12, 2021
6QNT
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BU of 6qnt by Molmil
Human Adenovirus type 3 fiber knob in complex with one copy of Desmoglein-2
分子名称: Desmoglein-2, Fiber protein
著者Effantin, G.
登録日2019-02-12
公開日2019-03-27
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献CryoEM structure of adenovirus type 3 fibre with desmoglein 2 shows an unusual mode of receptor engagement.
Nat Commun, 10, 2019
6QNU
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Human Adenovirus type 3 fiber knob in complex with two copies of Desmoglein-2
分子名称: Desmoglein-2, Fiber protein
著者Effantin, G.
登録日2019-02-12
公開日2019-03-27
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献CryoEM structure of adenovirus type 3 fibre with desmoglein 2 shows an unusual mode of receptor engagement.
Nat Commun, 10, 2019
7AGF
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HAd7 knob in complex with 3 EC2-EC3 modules of DSG-2
分子名称: Desmoglein-2, Fiber
著者Effantin, G, Vassal-Stermann, E, Fender, P.
登録日2020-09-22
公開日2020-10-14
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Binding Mechanism Elucidation of the Acute Respiratory Disease Causing Agent Adenovirus of Serotype 7 to Desmoglein-2.
Viruses, 12, 2020
7AGG
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BU of 7agg by Molmil
HAd7 knob in complex with 2 EC2-EC3 modules of DSG-2
分子名称: Desmoglein-2, Fiber
著者Effantin, G, Vassal-Stermann, E, Fender, P.
登録日2020-09-22
公開日2020-10-14
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Binding Mechanism Elucidation of the Acute Respiratory Disease Causing Agent Adenovirus of Serotype 7 to Desmoglein-2.
Viruses, 12, 2020
8QK3
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BU of 8qk3 by Molmil
Human Adenovirus type 11 fiber knob in complex with its cell receptors, Desmoglein-2 and CD46
分子名称: Desmoglein-2, Fiber protein, Membrane cofactor protein
著者Effantin, G.
登録日2023-09-14
公開日2023-11-01
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Toward the understanding of DSG2 and CD46 interaction with HAdV-11 fiber, a super-complex analysis.
J.Virol., 97, 2023
8QJX
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BU of 8qjx by Molmil
Human Adenovirus type 11 fiber knob in complex with two copies of its cell receptor, Desmoglein-2
分子名称: Desmoglein-2, Fiber protein
著者Effantin, G.
登録日2023-09-14
公開日2023-11-01
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Toward the understanding of DSG2 and CD46 interaction with HAdV-11 fiber, a super-complex analysis.
J.Virol., 97, 2023
8QJY
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BU of 8qjy by Molmil
Human Adenovirus type 11 fiber knob in complex with two copies of its cell receptor, Desmoglein-2
分子名称: Desmoglein-2, Fiber protein
著者Effantin, G.
登録日2023-09-14
公開日2023-11-01
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Toward the understanding of DSG2 and CD46 interaction with HAdV-11 fiber, a super-complex analysis.
J.Virol., 97, 2023
7K79
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BU of 7k79 by Molmil
CBF3
分子名称: Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, Suppressor of kinetochore protein 1
著者Ruifang, G, Yawen, B.
登録日2020-09-22
公開日2021-03-31
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation.
Nat Commun, 12, 2021
5NG5
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BU of 5ng5 by Molmil
multi-drug efflux; membrane transport; RND superfamily; Drug resistance
分子名称: 6-[2-(3,4-dimethoxyphenyl)ethylsulfanyl]-8-[4-(2-methoxyethyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile, Multidrug efflux pump accessory protein AcrZ, Multidrug efflux pump subunit AcrA, ...
著者Wang, Z, Fan, G, Hryc, C.F, Blaza, J.N, Serysheva, I.I, Schmid, M.F, Chiu, W, Luisi, B.F, Du, D.
登録日2017-03-16
公開日2017-04-19
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump.
Elife, 6, 2017
6MU1
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BU of 6mu1 by Molmil
Structure of full-length IP3R1 channel bound with Adenophostin A
分子名称: Adenophostin A, Inositol 1,4,5-trisphosphate receptor type 1
著者Serysheva, I.I, Fan, G, Baker, M.R, Wang, Z, Seryshev, A, Ludtke, S.J, Baker, M.L.
登録日2018-10-22
公開日2018-12-05
最終更新日2019-11-27
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Cryo-EM reveals ligand induced allostery underlying InsP3R channel gating.
Cell Res., 28, 2018
6MU2
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BU of 6mu2 by Molmil
Structure of full-length IP3R1 channel in the Apo-state
分子名称: Inositol 1,4,5-trisphosphate receptor type 1
著者Serysheva, I.I, Fan, G, Baker, M.R, Wang, Z, Seryshev, A, Ludtke, S.J, Baker, M.L.
登録日2018-10-22
公開日2018-12-05
最終更新日2019-11-27
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM reveals ligand induced allostery underlying InsP3R channel gating.
Cell Res., 28, 2018
7LHE
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BU of 7lhe by Molmil
Structure of full-length IP3R1 channel reconstituted into lipid nanodisc in the apo-state
分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, Inositol 1,4,5-trisphosphate receptor type 1, ZINC ION
著者Baker, M.R, Fan, G, Baker, M.L, Serysheva, I.I.
登録日2021-01-22
公開日2021-06-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structure of type 1 IP3R channel in a lipid bilayer
Commun Biol, 4, 2021
7LHF
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Structure of full-length IP3R1 channel solubilized in LNMG & lipid in the apo-state
分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, Inositol 1,4,5-trisphosphate receptor type 1, ZINC ION
著者Baker, M.R, Fan, G, Baker, M.L, Serysheva, I.I.
登録日2021-01-22
公開日2021-06-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.96 Å)
主引用文献Cryo-EM structure of type 1 IP3R channel in a lipid bilayer
Commun Biol, 4, 2021
5V5S
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BU of 5v5s by Molmil
multi-drug efflux; membrane transport; RND superfamily; Drug resistance
分子名称: Multidrug efflux pump subunit AcrA, Multidrug efflux pump subunit AcrB, Outer membrane protein TolC
著者wang, Z, fan, G, Hryc, C.F, Blaza, J.N, Serysheva, I.I, Schmid, M.F, Chiu, W, Luisi, B.F, Du, D.
登録日2017-03-15
公開日2017-04-19
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump.
Elife, 6, 2017
6R8N
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BU of 6r8n by Molmil
STRUCTURE DETERMINATION OF THE TETRAHEDRAL AMINOPEPTIDASE TET2 FROM P. HORIKOSHII BY USE OF COMBINED SOLID-STATE NMR, SOLUTION-STATE NMR AND EM DATA 4.1 A, FOLLOWED BY REAL_SPACE_REFINEMENT AT 4.1 A
分子名称: Tetrahedral aminopeptidase, ZINC ION
著者Colletier, J.-P, Gauto, D, Estrozi, L, Favier, A, Effantin, G, Schoehn, G, Boisbouvier, J, Schanda, P.
登録日2019-04-02
公開日2019-08-14
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (4.1 Å), SOLUTION NMR
主引用文献Integrated NMR and cryo-EM atomic-resolution structure determination of a half-megadalton enzyme complex.
Nat Commun, 10, 2019
7ZCH
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BU of 7zch by Molmil
CHMP2A-CHMP3 heterodimer (410 Angstrom diameter)
分子名称: Charged multivesicular body protein 2a, Charged multivesicular body protein 3
著者Azad, K, Desfosses, A, Effantin, G, Schoehn, G, Weissenhorn, W.
登録日2022-03-28
公開日2023-01-18
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage.
Nat.Struct.Mol.Biol., 30, 2023
7ZCG
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CHMP2A-CHMP3 heterodimer (430 Angstrom diameter)
分子名称: Charged multivesicular body protein 2a, Charged multivesicular body protein 3
著者Azad, K, Desfosses, A, Effantin, G, Schoehn, G, Weissenhorn, W.
登録日2022-03-28
公開日2023-01-18
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage.
Nat.Struct.Mol.Biol., 30, 2023

 

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