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PDB: 391 results
7WVY
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BU of 7wvy by Molmil
Cryo-EM structure of the human formyl peptide receptor 2 in complex with Abeta42 and Gi2
Descriptor: Amyloid-beta A4 protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B.
Deposit date:2022-02-11
Release date:2022-04-13
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin.
Nat Commun, 13, 2022
7WVW
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BU of 7wvw by Molmil
Cryo-EM structure of the human formyl peptide receptor 2 in complex with fMYFINILTL and Gi2
Descriptor: FME-TYR-PHE-ILE-ASN-ILE-LEU-THE-LEU, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B.
Deposit date:2022-02-11
Release date:2022-04-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin.
Nat Commun, 13, 2022
7WVU
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BU of 7wvu by Molmil
Cryo-EM structure of the human formyl peptide receptor 1 in complex with fMLF and Gi1
Descriptor: FME-LEU-PHE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B.
Deposit date:2022-02-11
Release date:2022-04-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin.
Nat Commun, 13, 2022
7WVV
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BU of 7wvv by Molmil
Cryo-EM structure of the human formyl peptide receptor 2 in complex with fMLFII and Gi2
Descriptor: FME-LEU-PHE-ILE-ILE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B.
Deposit date:2022-02-11
Release date:2022-04-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin.
Nat Commun, 13, 2022
7WVX
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BU of 7wvx by Molmil
Cryo-EM structure of the human formyl peptide receptor 2 in complex with fhumanin and Gi2
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-2, ...
Authors:Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B.
Deposit date:2022-02-11
Release date:2022-04-13
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin.
Nat Commun, 13, 2022
7FB3
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BU of 7fb3 by Molmil
SARS-CoV-2 spike protein in one-RBD weak state after CTSL-treatment
Descriptor: Spike glycoprotein
Authors:Zhu, Y, Tai, L.H, Sun, F.
Deposit date:2021-07-08
Release date:2022-07-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Novel sites for Cathepsin L cleavage in SARS-CoV-2 spike guide treatment strategies
To Be Published
7FB0
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BU of 7fb0 by Molmil
SARS-CoV-2 spike protein in closed state
Descriptor: Spike glycoprotein
Authors:Zhu, Y, Tai, L.H, Sun, F.
Deposit date:2021-07-08
Release date:2022-07-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Novel sites for Cathepsin L cleavage in SARS-CoV-2 spike guide treatment strategies
To Be Published
7FB1
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BU of 7fb1 by Molmil
SARS-CoV-2 spike protein in one-RBD open state
Descriptor: Spike glycoprotein
Authors:Zhu, Y, Tai, L.H, Sun, F.
Deposit date:2021-07-08
Release date:2022-07-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Novel sites for Cathepsin L cleavage in SARS-CoV-2 spike guide treatment strategies
To Be Published
7FB4
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BU of 7fb4 by Molmil
SARS-CoV-2 spike protein in two-RBD weak state after CTSL-treatment
Descriptor: Spike glycoprotein
Authors:Zhu, Y, Tai, L.H, Sun, F.
Deposit date:2021-07-08
Release date:2022-07-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Novel sites for Cathepsin L cleavage in SARS-CoV-2 spike guide treatment strategies
To Be Published
7Y37
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BU of 7y37 by Molmil
Structure of a triple-helix region of human collagen type V
Descriptor: A triple-helix region of human collagen type V
Authors:Zhu, Y, Yang, X, Sun, F.
Deposit date:2022-06-10
Release date:2023-07-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of a triple-helix region of human collagen type V
To Be Published
2Q8Y
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BU of 2q8y by Molmil
Structural insight into the enzymatic mechanism of the phophothreonine lyase
Descriptor: 27.5 kDa virulence protein, Mitogen-activated protein kinase 7
Authors:Zhu, Y.-Q, Wang, D.-C, Shao, F.
Deposit date:2007-06-12
Release date:2007-12-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the enzymatic mechanism of the pathogenic MAPK phosphothreonine lyase
Mol.Cell, 28, 2007
2P1W
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BU of 2p1w by Molmil
structure of the phosphothreonine lyase SpvC, the effector protein from Salmonella
Descriptor: 27.5 kDa virulence protein
Authors:Zhu, Y, Wang, D.C, Shao, F.
Deposit date:2007-03-06
Release date:2007-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the enzymatic mechanism of the pathogenic MAPK phosphothreonine lyase.
Mol.Cell, 28, 2007
8EF5
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BU of 8ef5 by Molmil
Fentanyl-bound mu-opioid receptor-Gi complex
Descriptor: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E.
Deposit date:2022-09-08
Release date:2022-11-09
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
8EF6
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BU of 8ef6 by Molmil
Morphine-bound mu-opioid receptor-Gi complex
Descriptor: (7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E.
Deposit date:2022-09-08
Release date:2022-11-09
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
8EFO
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BU of 8efo by Molmil
PZM21-bound mu-opioid receptor-Gi complex
Descriptor: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E.
Deposit date:2022-09-08
Release date:2022-11-09
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
8EFL
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BU of 8efl by Molmil
SR17018-bound mu-opioid receptor-Gi complex
Descriptor: 5,6-dichloro-1-{1-[(4-chlorophenyl)methyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E.
Deposit date:2022-09-08
Release date:2022-11-09
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
8EFB
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BU of 8efb by Molmil
Oliceridine-bound mu-opioid receptor-Gi complex
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E.
Deposit date:2022-09-08
Release date:2022-11-09
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
8EFQ
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BU of 8efq by Molmil
DAMGO-bound mu-opioid receptor-Gi complex
Descriptor: DAMGO, ETHANOLAMINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E.
Deposit date:2022-09-08
Release date:2022-11-09
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
6OMM
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BU of 6omm by Molmil
Cryo-EM structure of formyl peptide receptor 2/lipoxin A4 receptor in complex with Gi
Descriptor: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Zhuang, Y, Liu, H, de Waal, P.W, Zhou, X.E, Wang, L, Meng, X, Zhao, G, Kang, Y, Melcher, K, Xu, H.E, Zhang, C.
Deposit date:2019-04-19
Release date:2020-02-26
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Structure of formylpeptide receptor 2-Gicomplex reveals insights into ligand recognition and signaling.
Nat Commun, 11, 2020
7T6S
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BU of 7t6s by Molmil
Structure of the human FPR2-Gi complex with compound C43
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Zhuang, Y.W.
Deposit date:2021-12-14
Release date:2022-03-30
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2.
Nat Commun, 13, 2022
7T6V
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BU of 7t6v by Molmil
Structure of the human FPR2-Gi complex with fMLFII
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Zhuang, Y.W.
Deposit date:2021-12-14
Release date:2022-03-30
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2.
Nat Commun, 13, 2022
7T6U
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BU of 7t6u by Molmil
Structure of the human FPR2-Gi complex with CGEN-855A
Descriptor: B9-scFv, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Zhuang, Y.W.
Deposit date:2021-12-14
Release date:2022-03-30
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2.
Nat Commun, 13, 2022
7T6T
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BU of 7t6t by Molmil
Structure of the human FPR1-Gi complex with fMLFII
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Zhuang, Y.W.
Deposit date:2021-12-14
Release date:2022-03-30
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2.
Nat Commun, 13, 2022
7LJC
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BU of 7ljc by Molmil
Allosteric modulator LY3154207 binding to SKF-81297-bound dopamine receptor 1 in complex with miniGs protein
Descriptor: (1R)-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, ...
Authors:Zhuang, Y, Krumm, B, Zhang, H, Zhou, X.E, Wang, Y, Guo, J, Huang, X.-P, Liu, Y, Wang, L, Cheng, X, Jiang, Y, Jiang, H, Melcher, K, Zhang, C, Yi, W, Roth, B.L, Zhang, Y, Xu, H.E.
Deposit date:2021-01-28
Release date:2021-03-03
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
Cell Res., 31, 2021
7LJD
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BU of 7ljd by Molmil
Allosteric modulator LY3154207 binding to dopamine-bound dopamine receptor 1 in complex with miniGs protein
Descriptor: 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, D(1A) dopamine receptor, ...
Authors:Zhuang, Y, Krumm, B, Zhang, H, Zhou, X.E, Wang, Y, Guo, J, Huang, X.-P, Liu, Y, Wang, L, Cheng, X, Jiang, Y, Jiang, H, Melcher, K, Zhang, C, Yi, W, Roth, B.L, Zhang, Y, Xu, H.E.
Deposit date:2021-01-28
Release date:2021-03-03
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
Cell Res., 31, 2021

224004

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