7T6U

Structure of the human FPR2-Gi complex with CGEN-855A

Summary for 7T6U

• Entry DOI: 10.2210/pdb7t6u/pdb
• EMDB information: 25728
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• Functional Keywords: gpcr, membrane protein, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 157924.84

Authors

Zhuang, Y.W. (deposition date: 2021-12-14, release date: 2022-03-30, Last modification date: 2022-10-19)

• Primary citation: Zhuang, Y.,Wang, L.,Guo, J.,Sun, D.,Wang, Y.,Liu, W.,Xu, H.E.,Zhang, C.; Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2.; Nat Commun, 13:1054-1054, 2022; PubMed: 35217703; DOI: 10.1038/s41467-022-28586-0

Experimental method

ELECTRON MICROSCOPY (2.9 Å)