7T6U
Structure of the human FPR2-Gi complex with CGEN-855A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 353 | 40313.9 | 1 | UniProt (P63096) Pfam (PF00503) In PDB | Homo sapiens (Human) | Adenylate cyclase-inhibiting G alpha protein |
2 | B | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 353 | 39021.6 | 1 | UniProt (P54311) Pfam (PF00400) In PDB | Rattus | Transducin beta chain 1 |
3 | C | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 67 | 7432.6 | 1 | UniProt (P63212) Pfam (PF00631) In PDB | Bos taurus (Cattle) | G gamma-I |
4 | E | B9-scFv | polymer | 247 | 26323.3 | 1 | Rattus | ||
5 | L | Synthetic peptide | polymer | 8 | 1074.3 | 1 | Homo | ||
6 | R | N-formyl peptide receptor 2 | polymer | 390 | 43246.3 | 1 | UniProt (P25090) Pfam (PF00001) In PDB | Homo sapiens (Human) | FMLP-related receptor I,FMLP-R-I,Formyl peptide receptor-like 1,HM63,Lipoxin A4 receptor,LXA4 receptor,RFP |
7 | R | PALMITIC ACID | non-polymer | 256.4 | 2 | Chemie (PLM) |
Sequence modifications
A: 2 - 354 (UniProt: P63096)
B: 2 - 340 (UniProt: P54311)
R: 1 - 342 (UniProt: P25090)
PDB | External Database | Details |
---|---|---|
Ala 203 | Gly 203 | conflict |
Ser 326 | Ala 326 | conflict |
PDB | External Database | Details |
---|---|---|
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
Met -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
Leu -1 | - | expression tag |
Leu 0 | - | expression tag |
Gln 1 | - | expression tag |
Glu 6 | Gln 6 | conflict |
PDB | External Database | Details |
---|---|---|
Asp -47 | - | expression tag |
Tyr -46 | - | expression tag |
Lys -45 | - | expression tag |
Asp -44 | - | expression tag |
Asp -43 | - | expression tag |
Asp -42 | - | expression tag |
Asp -41 | - | expression tag |
Val -40 | - | expression tag |
Asp -39 | - | expression tag |
Met -38 | - | expression tag |
Gly -37 | - | expression tag |
Gln -36 | - | expression tag |
Pro -35 | - | expression tag |
Gly -34 | - | expression tag |
Asn -33 | - | expression tag |
Gly -32 | - | expression tag |
Ser -31 | - | expression tag |
Ala -30 | - | expression tag |
Phe -29 | - | expression tag |
Leu -28 | - | expression tag |
Leu -27 | - | expression tag |
Ala -26 | - | expression tag |
Pro -25 | - | expression tag |
Asn -24 | - | expression tag |
Gly -23 | - | expression tag |
Ser -22 | - | expression tag |
His -21 | - | expression tag |
Ala -20 | - | expression tag |
Pro -19 | - | expression tag |
Asp -18 | - | expression tag |
His -17 | - | expression tag |
Asp -16 | - | expression tag |
Val -15 | - | expression tag |
Thr -14 | - | expression tag |
Gln -13 | - | expression tag |
Gln -12 | - | expression tag |
Arg -11 | - | expression tag |
Asp -10 | - | expression tag |
Glu -9 | - | expression tag |
Glu -8 | - | expression tag |
Asn -7 | - | expression tag |
Leu -6 | - | expression tag |
Tyr -5 | - | expression tag |
Phe -4 | - | expression tag |
Gln -3 | - | expression tag |
Gly -2 | - | expression tag |
Ala -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 157412.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 512.8 | |
All* | Total formula weight | 157924.8 |