5MWZ
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5NLK
| Crystal structure of CREBBP bromodomain complexd with US13A | 分子名称: | CREB-binding protein, ~{N}-[3-acetamido-5-[(5-ethanoyl-2-ethoxy-phenyl)carbamoyl]phenyl]furan-2-carboxamide | 著者 | Zhu, J, Caflisch, A. | 登録日 | 2017-04-04 | 公開日 | 2018-02-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Chemical Space Expansion of Bromodomain Ligands Guided by in Silico Virtual Couplings (AutoCouple). ACS Cent Sci, 4, 2018
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5O55
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5O5A
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5O97
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5O4S
| Crystal structure of the human BRPF1 bromodomain in complex with BZ135 | 分子名称: | NITRATE ION, Peregrin, ~{N}-[1,4-dimethyl-7-morpholin-4-yl-2,3-bis(oxidanylidene)quinoxalin-6-yl]-5,6,7,8-tetrahydronaphthalene-2-sulfonamide | 著者 | Zhu, J, Caflisch, A. | 登録日 | 2017-05-30 | 公開日 | 2018-06-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure-based discovery of selective BRPF1 bromodomain inhibitors. Eur J Med Chem, 155, 2018
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5O4T
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5O5F
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5O5H
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3WP1
| Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl | 分子名称: | Disks large homolog 4, Lethal(2) giant larvae protein homolog 2, SULFATE ION | 著者 | Zhu, J, Shang, Y, Wan, Q, Xia, Y, Chen, J, Du, Q, Zhang, M. | 登録日 | 2014-01-08 | 公開日 | 2014-03-19 | 最終更新日 | 2014-04-30 | 実験手法 | X-RAY DIFFRACTION (2.804 Å) | 主引用文献 | Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl Cell Res., 24, 2014
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3WP0
| Crystal structure of Dlg GK in complex with a phosphor-Lgl2 peptide | 分子名称: | Disks large homolog 4, GLYCEROL, Lethal(2) giant larvae protein homolog 2 | 著者 | Zhu, J, Shang, Y, Wan, Q, Xia, Y, Chen, J, Du, Q, Zhang, M. | 登録日 | 2014-01-08 | 公開日 | 2014-03-19 | 最終更新日 | 2014-04-30 | 実験手法 | X-RAY DIFFRACTION (2.039 Å) | 主引用文献 | Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl Cell Res., 24, 2014
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3FCU
| Structure of headpiece of integrin aIIBb3 in open conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, CALCIUM ION, ... | 著者 | Zhu, J, Luo, B.-H, Xiao, T, Zhang, C, Nishida, N, Springer, T.A. | 登録日 | 2008-11-22 | 公開日 | 2009-01-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces. Mol.Cell, 32, 2008
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3FCS
| Structure of complete ectodomain of integrin aIIBb3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Zhu, J, Luo, B.-H, Xiao, T, Zhang, C, Nishida, N, Springer, T.A. | 登録日 | 2008-11-22 | 公開日 | 2009-01-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces. Mol.Cell, 32, 2008
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1ZNN
| Structure of the synthase subunit of PLP synthase | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, PLP SYNTHASE, SULFATE ION | 著者 | Zhu, J, Burgner, J.W, Harms, E, Belitsky, B.R, Smith, J.L. | 登録日 | 2005-05-11 | 公開日 | 2005-05-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A New Arrangement of (beta/alpha)8 Barrels in the Synthase Subunit of PLP Synthase. J.Biol.Chem., 280, 2005
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4YLM
| Structure of PvcB, an Fe, alpha-ketoglutarate dependent oxygenase from an isonitrile synthetic pathway | 分子名称: | GLYCEROL, Pyoverdine biosynthesis protein PvcB | 著者 | Zhu, J, Lippa, G.M, Gulick, A.M, Tipton, P.A. | 登録日 | 2015-03-05 | 公開日 | 2015-04-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Examining Reaction Specificity in PvcB, a Source of Diversity in Isonitrile-Containing Natural Products. Biochemistry, 54, 2015
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5YPR
| Crystal Structure of PSD-95 SH3-GK domain in complex with a synthesized inhibitor | 分子名称: | Disks large homolog 4, Synthesized GK inhibitor | 著者 | Zhu, J, Zhou, Q, Shang, Y, Weng, Z, Zhu, R, Zhang, M. | 登録日 | 2017-11-02 | 公開日 | 2018-03-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.349 Å) | 主引用文献 | Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs. Cell Rep, 21, 2017
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4XEJ
| IRES bound to bacterial Ribosome | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Zhu, J, Korostelev, A, Noller, H.F, Donohue, J.P. | 登録日 | 2014-12-23 | 公開日 | 2015-02-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Initiation of translation in bacteria by a structured eukaryotic IRES RNA. Nature, 519, 2015
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6QST
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6JMT
| Crystal structure of GIT/PIX complex | 分子名称: | ARF GTPase-activating protein GIT2, ZINC ION, beta PIX | 著者 | Zhu, J, Lin, L, Xia, Y, Zhang, R, Zhang, M. | 登録日 | 2019-03-13 | 公開日 | 2020-05-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling. Mol.Cell, 79, 2020
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6JMU
| Crystal structure of GIT1/Paxillin complex | 分子名称: | ARF GTPase-activating protein GIT1, Paxillin | 著者 | Zhu, J, Lin, L, Xia, Y, Zhang, R, Zhang, M. | 登録日 | 2019-03-13 | 公開日 | 2020-05-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling. Mol.Cell, 79, 2020
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7TCT
| Integrin alaphIIBbeta3 complex with UR2922 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Zhu, J, Lin, F.-Y, Zhu, J, Springer, T.A. | 登録日 | 2021-12-28 | 公開日 | 2022-08-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7TD8
| Integrin alaphIIBbeta3 complex with Tirofiban | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Zhu, J, Lin, F.-Y, Zhu, J, Springer, T.A. | 登録日 | 2021-12-30 | 公開日 | 2022-08-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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3T3P
| A Novel High Affinity Integrin alphaIIbbeta3 Receptor Antagonist That Unexpectedly Displaces Mg2+ from the beta3 MIDAS | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Zhu, J, Zhu, J, Springer, T.A. | 登録日 | 2011-07-25 | 公開日 | 2012-03-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure-Guided Design of a High-Affinity Platelet Integrin alphaIIbbeta3 Receptor Antagonist That Disrupts Mg2+ Binding to the MIDAS Sci Transl Med, 4, 2012
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3T3M
| A Novel High Affinity Integrin alphaIIbbeta3 Receptor Antagonist That Unexpectedly Displaces Mg2+ from the beta3 MIDAS | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Zhu, J, Zhu, J, Springer, T.A. | 登録日 | 2011-07-25 | 公開日 | 2012-03-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-Guided Design of a High-Affinity Platelet Integrin alphaIIbbeta3 Receptor Antagonist That Disrupts Mg2+ Binding to the MIDAS Sci Transl Med, 4, 2012
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6FQO
| Crystal structure of CREBBP bromodomain complexd with DT29 | 分子名称: | 1,2-ETHANEDIOL, CREB-binding protein, ~{N}-[3-(2,5-dimethyl-3-oxidanylidene-1,2-oxazol-4-yl)-5-(5-ethanoyl-2-ethoxy-phenyl)phenyl]furan-2-carboxamide | 著者 | Zhu, J, Caflisch, A. | 登録日 | 2018-02-14 | 公開日 | 2018-08-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules. ACS Med Chem Lett, 9, 2018
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