Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 318 件

7XHQ
DownloadVisualize
BU of 7xhq by Molmil
Small-molecule Allosteric Regulation Mechanism of SHP2
分子名称: 2-[(3S,4R)-4-azanyl-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-5-[2,3-bis(chloranyl)phenyl]-3-methyl-pyrrolo[2,1-f][1,2,4]triazin-4-one, Tyrosine-protein phosphatase non-receptor type 11
著者Luo, Y, Zhu, J, Yu, K, Liu, B.
登録日2022-04-09
公開日2023-02-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of the SHP2 allosteric inhibitor 2-((3R,4R)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl)-5-(2,3-dichlorophenyl)-3-methylpyrrolo[2,1-f][1,2,4] triazin-4(3H)-one.
J Enzyme Inhib Med Chem, 38, 2023
7U08
DownloadVisualize
BU of 7u08 by Molmil
Structure of CD148 fibronectin type III domain 1 and 2
分子名称: PLATINUM (II) ION, Receptor-type tyrosine-protein phosphatase eta
著者Zhou, D, Zhu, J.
登録日2022-02-17
公開日2023-02-22
実験手法X-RAY DIFFRACTION (3.30691743 Å)
主引用文献Structure of CD148 fibronectin type III domain 1 and 2
To Be Published
4JHR
DownloadVisualize
BU of 4jhr by Molmil
An auto-inhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs
分子名称: G-protein-signaling modulator 2
著者Pan, Z, Zhu, J, Shang, Y, Wei, Z, Jia, M, Xia, C, Wen, W, Wang, W, Zhang, M.
登録日2013-03-05
公開日2013-06-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献An autoinhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs
Structure, 21, 2013
7U01
DownloadVisualize
BU of 7u01 by Molmil
Structure of CD148 fibronectin type III domain 2
分子名称: Receptor-type tyrosine-protein phosphatase eta
著者Zhou, D, Zhu, J.
登録日2022-02-17
公開日2023-02-22
実験手法X-RAY DIFFRACTION (2.297079 Å)
主引用文献Structure of CD148 fibronectin type III domain 1 and 2
To Be Published
4G5S
DownloadVisualize
BU of 4g5s by Molmil
Structure of LGN GL3/Galphai3 complex
分子名称: CITRIC ACID, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ...
著者Jia, M, Li, J, Zhu, J, Wen, W, Zhang, M, Wang, W.
登録日2012-07-18
公開日2012-09-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.62 Å)
主引用文献Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
7W5E
DownloadVisualize
BU of 7w5e by Molmil
Oxidase ChaP D49L mutant
分子名称: ChaP, FE (III) ION
著者Wang, Y, Zheng, W, Meng, Z, Jin, Y, Zhu, J, Tan, R.
登録日2021-11-30
公開日2022-10-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Alteration of the Catalytic Reaction Trajectory of a Vicinal Oxygen Chelate Enzyme by Directed Evolution.
Angew.Chem.Int.Ed.Engl., 61, 2022
6UYD
DownloadVisualize
BU of 6uyd by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2mc3-v1 redesigned core from genotype 1a bound to broadly neutralizing antibody AR3C
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Tzarum, N, Wilson, I.A, Zhu, J.
登録日2019-11-13
公開日2020-04-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.897 Å)
主引用文献Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines.
Sci Adv, 6, 2020
6UYM
DownloadVisualize
BU of 6uym by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2mc3-v6 redesigned core from genotype 1a bound to broadly neutralizing antibody AR3C
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Tzarum, N, Wilson, I.A, Zhu, J.
登録日2019-11-13
公開日2020-04-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.848 Å)
主引用文献Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines.
Sci Adv, 6, 2020
7WB2
DownloadVisualize
BU of 7wb2 by Molmil
Oxidase ChaP-D49L/Y109F mutant
分子名称: ChaP, FE (III) ION
著者Zong, Y, Zheng, W, Wang, Y, Zhu, J, Tan, R.
登録日2021-12-15
公開日2022-05-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Alteration of the Catalytic Reaction Trajectory of a Vicinal Oxygen Chelate Enzyme by Directed Evolution.
Angew.Chem.Int.Ed.Engl., 61, 2022
6UYG
DownloadVisualize
BU of 6uyg by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2c3 core from genotype 6a bound to broadly neutralizing antibody AR3A and non neutralizing antibody E1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Tzarum, N, Wilson, I.A, Zhu, J.
登録日2019-11-13
公開日2020-04-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.375 Å)
主引用文献Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines.
Sci Adv, 6, 2020
6UYF
DownloadVisualize
BU of 6uyf by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2mc3-v1 redesigned core from genotype 6a bound to broadly neutralizing antibody AR3B
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Tzarum, N, Wilson, I.A, Zhu, J.
登録日2019-11-13
公開日2020-04-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines.
Sci Adv, 6, 2020
6VYP
DownloadVisualize
BU of 6vyp by Molmil
Crystal structure of the LSD1/CoREST histone demethylase bound to its nucleosome substrate
分子名称: DNA (191-MER), FLAVIN-ADENINE DINUCLEOTIDE, Histone H2A type 1, ...
著者Kim, S, Zhu, J, Eek, P, Yennawar, N, Song, T.
登録日2020-02-27
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.99 Å)
主引用文献Crystal Structure of the LSD1/CoREST Histone Demethylase Bound to Its Nucleosome Substrate.
Mol.Cell, 78, 2020
5J97
DownloadVisualize
BU of 5j97 by Molmil
Dimerization domain of cytoplasmic activation/proliferation-associated protein-2 (caprin-2)
分子名称: Caprin-2
著者Wu, Y, Zhu, J, Huang, X, Du, Z.
登録日2016-04-08
公開日2017-08-09
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Dimerization domain of cytoplasmic activation/proliferation-associated protein-2 (caprin-2)
To Be Published
7EP7
DownloadVisualize
BU of 7ep7 by Molmil
The complex structure of Gpsm2 and Whirlin
分子名称: G-protein-signaling modulator 2, Whirlin
著者Lin, L, Shi, Y, Wang, C, Zhu, J.
登録日2021-04-26
公開日2022-05-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Promotion of row 1-specific tip complex condensates by Gpsm2-G alpha i provides insights into row identity of the tallest stereocilia.
Sci Adv, 8, 2022
4G5R
DownloadVisualize
BU of 4g5r by Molmil
Structure of LGN GL4/Galphai3 complex
分子名称: CITRIC ACID, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ...
著者Jia, M, Li, J, Zhu, J, Wen, W, Zhang, M, Wang, W.
登録日2012-07-18
公開日2012-09-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.481 Å)
主引用文献Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
4G5Q
DownloadVisualize
BU of 4g5q by Molmil
Structure of LGN GL4/Galphai1 complex
分子名称: CITRIC ACID, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ...
著者Jia, M, Li, J, Zhu, J, Wen, W, Zhang, M, Wang, W.
登録日2012-07-18
公開日2012-09-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
7JPI
DownloadVisualize
BU of 7jpi by Molmil
Crystal structure of EBOV glycoprotein with modified HR2 stalk at 2.3A resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, ...
著者Chaudhary, A, Stanfield, R.L, Wilson, I.A, Zhu, J.
登録日2020-08-08
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines.
Nat Commun, 12, 2021
7JPH
DownloadVisualize
BU of 7jph by Molmil
Crystal structure of EBOV glycoprotein with modified HR1c and HR2 stalk at 3.2 A resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, ...
著者Chaudhary, A, Stanfield, R.L, Wilson, I.A, Zhu, J.
登録日2020-08-08
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.195 Å)
主引用文献Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines.
Nat Commun, 12, 2021
4H6J
DownloadVisualize
BU of 4h6j by Molmil
Identification of Cys 255 in HIF-1 as a novel site for development of covalent inhibitors of HIF-1 /ARNT PasB domain protein-protein interaction.
分子名称: ARYL HYDROCARBON NUCLEAR TRANSLOCATOR, HYPOXIA INDUCIBLE FACTOR 1-ALPHA
著者Cardoso, R, Love, R.A, Nilsson, C, Bergqvist, S, Nowlin, D, Yan, J, Liu, K, Zhu, J, Chen, P, Deng, Y.-L, Dyson, H.J, Greig, M.J, Brooun, A.
登録日2012-09-19
公開日2012-12-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Identification of Cys255 in HIF-1 alpha as a novel site for development of covalent inhibitors of HIF-1 alpha /ARNT PasB domain protein-protein interaction.
Protein Sci., 21, 2012
7K5W
DownloadVisualize
BU of 7k5w by Molmil
Cryo-EM structure of heterologous protein complex loaded Thermotoga maritima encapsulin capsid
分子名称: Maritimacin
著者Xiong, X, Sun, C, Vago, F.S, Klose, T, Zhu, J, Jiang, W.
登録日2020-09-17
公開日2020-10-07
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.87 Å)
主引用文献Cryo-EM Structure of Heterologous Protein Complex Loaded Thermotoga Maritima Encapsulin Capsid.
Biomolecules, 10, 2020
4HK5
DownloadVisualize
BU of 4hk5 by Molmil
Crystal structure of Cordyceps militaris IDCase in apo form
分子名称: Uracil-5-carboxylate decarboxylase, ZINC ION
著者Xu, S, Zhu, J, Ding, J.
登録日2012-10-15
公開日2013-09-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4HK7
DownloadVisualize
BU of 4hk7 by Molmil
Crystal structure of Cordyceps militaris IDCase in complex with uracil
分子名称: URACIL, Uracil-5-carboxylate decarboxylase, ZINC ION
著者Xu, S, Zhu, J, Ding, J.
登録日2012-10-15
公開日2013-09-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.189 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4G5O
DownloadVisualize
BU of 4g5o by Molmil
Structure of LGN GL4/Galphai3(Q147L) complex
分子名称: CITRIC ACID, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ...
著者Jia, M, Li, J, Zhu, J, Wen, W, Zhang, M, Wang, W.
登録日2012-07-18
公開日2012-09-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
4HK6
DownloadVisualize
BU of 4hk6 by Molmil
Crystal structure of Cordyceps militaris IDCase in complex with 5-nitro-uracil
分子名称: 5-nitrouracil, Uracil-5-carboxylate decarboxylase, ZINC ION
著者Xu, S, Zhu, J, Ding, J.
登録日2012-10-15
公開日2013-09-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4HJW
DownloadVisualize
BU of 4hjw by Molmil
Crystal structure of Metarhizium anisopliae IDCase in apo form
分子名称: Uracil-5-carboxylate decarboxylase, ZINC ION
著者Xu, S, Zhu, J, Ding, J.
登録日2012-10-14
公開日2013-09-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013

222926

件を2024-07-24に公開中

PDB statisticsPDBj update infoContact PDBjnumon