3UNP
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![BU of 3unp by Molmil](/molmil-images/mine/3unp) | Structure of human SUN2 SUN domain | Descriptor: | ACETYL GROUP, SUN domain-containing protein 2 | Authors: | Zhou, Z.C, Greene, M.I. | Deposit date: | 2011-11-16 | Release date: | 2011-12-21 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Structure of Sad1-UNC84 homology (SUN) domain defines features of molecular bridge in nuclear envelope J.Biol.Chem., 287, 2012
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4FZA
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![BU of 4fza by Molmil](/molmil-images/mine/4fza) | Crystal structure of MST4-MO25 complex | Descriptor: | Calcium-binding protein 39, GLYCEROL, Serine/threonine-protein kinase MST4 | Authors: | Shi, Z.B, Zhou, Z.C. | Deposit date: | 2012-07-06 | Release date: | 2013-03-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Structure of the MST4 in Complex with MO25 Provides Insights into Its Activation Mechanism Structure, 21, 2013
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3B94
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![BU of 3b94 by Molmil](/molmil-images/mine/3b94) | Crystal structure of human GITRL | Descriptor: | Tumor necrosis factor ligand superfamily member 18 | Authors: | Song, X.M, Zhou, Z.C. | Deposit date: | 2007-11-02 | Release date: | 2008-02-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of human GITRL TO BE PUBLISHED
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3B93
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![BU of 3b93 by Molmil](/molmil-images/mine/3b93) | crystal structure of human GITRL | Descriptor: | Tumor necrosis factor ligand superfamily member 18 | Authors: | Song, X.M, Zhou, Z.C. | Deposit date: | 2007-11-02 | Release date: | 2008-02-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | crystal structure of human GITRL To be Published
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6AKK
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![BU of 6akk by Molmil](/molmil-images/mine/6akk) | Crystal structure of the second Coiled-coil domain of SIKE1 | Descriptor: | GLYCEROL, Suppressor of IKBKE 1 | Authors: | Zhou, L, Chen, M, Zhou, Z.C. | Deposit date: | 2018-09-02 | Release date: | 2019-01-16 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling. Cell Discov, 5, 2019
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6AKL
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![BU of 6akl by Molmil](/molmil-images/mine/6akl) | Crystal structure of Striatin3 in complex with SIKE1 Coiled-coil domain | Descriptor: | Striatin-3, Suppressor of IKBKE 1 | Authors: | Zhou, L, Chen, M, Zhou, Z.C. | Deposit date: | 2018-09-02 | Release date: | 2019-01-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling. Cell Discov, 5, 2019
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6AKM
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![BU of 6akm by Molmil](/molmil-images/mine/6akm) | Crystal structure of SLMAP-SIKE1 complex | Descriptor: | GLYCEROL, Sarcolemmal membrane-associated protein, Suppressor of IKBKE 1 | Authors: | Ma, J, Chen, M, Zhou, Z.C. | Deposit date: | 2018-09-02 | Release date: | 2019-01-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling. Cell Discov, 5, 2019
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5GZB
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![BU of 5gzb by Molmil](/molmil-images/mine/5gzb) | Crystal Structure of Transcription Factor TEAD4 in Complex with M-CAT DNA | Descriptor: | DNA (5'-D(*GP*AP*GP*AP*GP*GP*AP*AP*TP*GP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*CP*AP*TP*TP*CP*CP*TP*CP*TP*C)-3'), GLYCEROL, ... | Authors: | He, F, Shi, Z.B, Zhou, Z.C. | Deposit date: | 2016-09-28 | Release date: | 2017-04-19 | Last modified: | 2017-08-09 | Method: | X-RAY DIFFRACTION (2.704 Å) | Cite: | DNA-binding mechanism of the Hippo pathway transcription factor TEAD4 Oncogene, 36, 2017
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4O27
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![BU of 4o27 by Molmil](/molmil-images/mine/4o27) | Crystal structure of MST3-MO25 complex with WIF motif | Descriptor: | 5-mer peptide from serine/threonine-protein kinase 24, ADENOSINE-5'-DIPHOSPHATE, Calcium-binding protein 39, ... | Authors: | Hao, Q, Feng, M, Zhou, Z.C. | Deposit date: | 2013-12-16 | Release date: | 2014-12-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.185 Å) | Cite: | Structural insights into regulatory mechanisms of MO25-mediated kinase activation. J.Struct.Biol., 186, 2014
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4NZW
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![BU of 4nzw by Molmil](/molmil-images/mine/4nzw) | Crystal Structure of STK25-MO25 Complex | Descriptor: | 5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE, Calcium-binding protein 39, Serine/threonine-protein kinase 25 | Authors: | Feng, M, Hao, Q, Zhou, Z.C. | Deposit date: | 2013-12-13 | Release date: | 2014-12-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.583 Å) | Cite: | Structural insights into regulatory mechanisms of MO25-mediated kinase activation. J.Struct.Biol., 186, 2014
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4FZF
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![BU of 4fzf by Molmil](/molmil-images/mine/4fzf) | Crystal structure of MST4-MO25 complex with DKI | Descriptor: | 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE, Calcium-binding protein 39, Serine/threonine-protein kinase MST4 | Authors: | Shi, Z.B, Zhou, Z.C. | Deposit date: | 2012-07-06 | Release date: | 2013-03-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.64 Å) | Cite: | Structure of the MST4 in Complex with MO25 Provides Insights into Its Activation Mechanism Structure, 21, 2013
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4GEH
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![BU of 4geh by Molmil](/molmil-images/mine/4geh) | |
4FZD
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![BU of 4fzd by Molmil](/molmil-images/mine/4fzd) | Crystal structure of MST4-MO25 complex with WSF motif | Descriptor: | C-terminal peptide from Serine/threonine-protein kinase MST4, Calcium-binding protein 39, GLYCEROL, ... | Authors: | Shi, Z.B, Zhou, Z.C. | Deposit date: | 2012-07-06 | Release date: | 2013-03-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Structure of the MST4 in Complex with MO25 Provides Insights into Its Activation Mechanism Structure, 21, 2013
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4I1L
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![BU of 4i1l by Molmil](/molmil-images/mine/4i1l) | Structural and Biological Features of FOXP3 Dimerization Relevant to Regulatory T Cell Function | Descriptor: | ACETATE ION, Forkhead box protein P3, MAGNESIUM ION, ... | Authors: | Song, X.M, Greene, M.I, Zhou, Z.C. | Deposit date: | 2012-11-21 | Release date: | 2012-12-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and biological features of FOXP3 dimerization relevant to regulatory T cell function. Cell Rep, 1, 2012
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4HKD
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![BU of 4hkd by Molmil](/molmil-images/mine/4hkd) | |
6A8W
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![BU of 6a8w by Molmil](/molmil-images/mine/6a8w) | |
6IUR
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![BU of 6iur by Molmil](/molmil-images/mine/6iur) | A phosphatase complex STRN3-PP2Aa | Descriptor: | PP2A scaffolding subunit, PROPANE, Striatin-3 | Authors: | Tang, Y, Zhou, Z.C. | Deposit date: | 2018-11-30 | Release date: | 2019-12-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.33 Å) | Cite: | Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer. Cancer Cell, 38, 2020
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4RV0
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![BU of 4rv0 by Molmil](/molmil-images/mine/4rv0) | Crystal structure of TN complex | Descriptor: | Nuclear protein localization protein 4 homolog, SULFATE ION, Transitional endoplasmic reticulum ATPase TER94 | Authors: | Hao, Q, Jiao, S, Shi, Z.B, Zhou, Z.C. | Deposit date: | 2014-11-23 | Release date: | 2015-11-25 | Method: | X-RAY DIFFRACTION (1.998 Å) | Cite: | Crystal structure of TN complex To be Published
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5YF4
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![BU of 5yf4 by Molmil](/molmil-images/mine/5yf4) | A kinase complex MST4-MOB4 | Descriptor: | MOB-like protein phocein, Peptide from Serine/threonine-protein kinase 26, ZINC ION | Authors: | Chen, M, Zhou, Z.C. | Deposit date: | 2017-09-20 | Release date: | 2018-08-15 | Last modified: | 2018-09-26 | Method: | X-RAY DIFFRACTION (1.897 Å) | Cite: | The MST4-MOB4 complex disrupts the MST1-MOB1 complex in the Hippo-YAP pathway and plays a pro-oncogenic role in pancreatic cancer. J. Biol. Chem., 293, 2018
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4NT4
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![BU of 4nt4 by Molmil](/molmil-images/mine/4nt4) | Crystal structure of the kinase domain of Gilgamesh isoform I from Drosophila melanogaster | Descriptor: | GLYCEROL, Gilgamesh, isoform I, ... | Authors: | Chen, C.C, Shi, Z.B, Zhou, Z.C. | Deposit date: | 2013-11-30 | Release date: | 2014-04-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Structure of the kinase domain of Gilgamesh from Drosophila melanogaster Acta Crystallogr.,Sect.F, 70, 2014
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4HK1
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![BU of 4hk1 by Molmil](/molmil-images/mine/4hk1) | |
5XY9
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![BU of 5xy9 by Molmil](/molmil-images/mine/5xy9) | Structure of the MST4 and 14-3-3 complex | Descriptor: | 14-3-3 protein zeta/delta, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, GLYCEROL, ... | Authors: | Shi, Z.B, Zhou, Z.C. | Deposit date: | 2017-07-06 | Release date: | 2018-07-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.303 Å) | Cite: | Structure of the MST4 and 14-3-3 complex To Be Published
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