7X1U
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![BU of 7x1u by Molmil](/molmil-images/mine/7x1u) | Structure of Thyrotropin-Releasing Hormone Receptor bound with an Endogenous Peptide Agonist TRH. | Descriptor: | Endogenous Peptide Agonist TRH, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Yang, F, Zhang, H.H, Meng, X.Y, Li, Y.G, Zhou, Y.X, Ling, S.L, Liu, L, Shi, P, Tian, C.L. | Deposit date: | 2022-02-24 | Release date: | 2022-08-31 | Last modified: | 2022-09-14 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Structural insights into thyrotropin-releasing hormone receptor activation by an endogenous peptide agonist or its orally administered analogue. Cell Res., 32, 2022
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7XAT
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![BU of 7xat by Molmil](/molmil-images/mine/7xat) | Structure of somatostatin receptor 2 bound with SST14. | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Bo, Q, Yang, F, Li, Y.G, Meng, X.Y, Zhang, H.H, Zhou, Y.X, Ling, S.L, Sun, D.M, Lv, P, Liu, L, Shi, P, Tian, C.L. | Deposit date: | 2022-03-19 | Release date: | 2022-08-31 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Structural insights into the activation of somatostatin receptor 2 by cyclic SST analogues. Cell Discov, 8, 2022
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7XAU
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![BU of 7xau by Molmil](/molmil-images/mine/7xau) | Structure of somatostatin receptor 2 bound with octreotide. | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Bo, Q, Yang, F, Li, Y.G, Meng, X.Y, Zhang, H.H, Zhou, Y.X, Ling, S.L, Sun, D.M, Lv, P, Liu, L, Shi, P, Tian, C.L. | Deposit date: | 2022-03-19 | Release date: | 2022-08-31 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | Structural insights into the activation of somatostatin receptor 2 by cyclic SST analogues. Cell Discov, 8, 2022
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7XAV
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![BU of 7xav by Molmil](/molmil-images/mine/7xav) | Structure of somatostatin receptor 2 bound with lanreotide. | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Bo, Q, Yang, F, Li, Y.G, Meng, X.Y, Zhang, H.H, Zhou, Y.X, Ling, S.L, Sun, D.M, Lv, P, Liu, L, Shi, P, Tian, C.L. | Deposit date: | 2022-03-19 | Release date: | 2022-08-31 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Structural insights into the activation of somatostatin receptor 2 by cyclic SST analogues. Cell Discov, 8, 2022
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7X1T
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![BU of 7x1t by Molmil](/molmil-images/mine/7x1t) | Structure of Thyrotropin-Releasing Hormone Receptor bound with Taltirelin. | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ScFv16, ... | Authors: | Yang, F, Zhang, H.H, Meng, X.Y, Li, Y.G, Zhou, Y.X, Ling, S.L, Liu, L, Shi, P, Tian, C.L. | Deposit date: | 2022-02-24 | Release date: | 2022-08-31 | Last modified: | 2022-09-14 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Structural insights into thyrotropin-releasing hormone receptor activation by an endogenous peptide agonist or its orally administered analogue. Cell Res., 32, 2022
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8J8Q
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![BU of 8j8q by Molmil](/molmil-images/mine/8j8q) | Structure of the four-component Paf1 complex from Saccharomyces eubayanus | Descriptor: | CDC73-like protein, CTR9-like protein, PAF1-like protein, ... | Authors: | Wang, Z, Qin, Y, Zhou, Y, Cao, Y. | Deposit date: | 2023-05-02 | Release date: | 2023-05-24 | Last modified: | 2023-06-14 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Structural Basis of the Transcriptional Elongation Factor Paf1 Core Complex from Saccharomyces eubayanus . Int J Mol Sci, 24, 2023
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8J8P
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![BU of 8j8p by Molmil](/molmil-images/mine/8j8p) | Structure of the four-component Paf1 complex from Saccharomyces eubayanus | Descriptor: | CDC73-like protein, CTR9-like protein, PAF1-like protein, ... | Authors: | Wang, Z, Qin, Y, Zhou, Y, Cao, Y. | Deposit date: | 2023-05-02 | Release date: | 2023-05-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Basis of the Transcriptional Elongation Factor Paf1 Core Complex from Saccharomyces eubayanus . Int J Mol Sci, 24, 2023
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5Y2A
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![BU of 5y2a by Molmil](/molmil-images/mine/5y2a) | Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 2 | Descriptor: | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, insect group II chitinase | Authors: | Chen, W, Qu, M.B, Zhou, Y, Yang, Q. | Deposit date: | 2017-07-24 | Release date: | 2018-01-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural analysis of group II chitinase (ChtII) catalysis completes the puzzle of chitin hydrolysis in insects J. Biol. Chem., 293, 2018
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5Y29
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![BU of 5y29 by Molmil](/molmil-images/mine/5y29) | Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, insect group II chitinase | Authors: | Chen, W, Qu, M.B, Zhou, Y, Yang, Q. | Deposit date: | 2017-07-24 | Release date: | 2018-01-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural analysis of group II chitinase (ChtII) catalysis completes the puzzle of chitin hydrolysis in insects J. Biol. Chem., 293, 2018
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5Z34
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![BU of 5z34 by Molmil](/molmil-images/mine/5z34) | |
5Y2B
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![BU of 5y2b by Molmil](/molmil-images/mine/5y2b) | Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 1 in complex with HEPTA-N-ACETYLCHITOOCTAOSE (NAG)7 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, insect group II chitinase | Authors: | Chen, W, Qu, M.B, Zhou, Y, Yang, Q. | Deposit date: | 2017-07-24 | Release date: | 2018-01-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural analysis of group II chitinase (ChtII) catalysis completes the puzzle of chitin hydrolysis in insects J. Biol. Chem., 293, 2018
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5Y2C
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![BU of 5y2c by Molmil](/molmil-images/mine/5y2c) | Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 2 E2180L mutant in complex with PENTA-N-ACETYLCHITOOCTAOSE (NAG)5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, insect group II chitinase | Authors: | Chen, W, Qu, M.B, Zhou, Y, Yang, Q. | Deposit date: | 2017-07-24 | Release date: | 2018-01-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural analysis of group II chitinase (ChtII) catalysis completes the puzzle of chitin hydrolysis in insects J. Biol. Chem., 293, 2018
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7JKB
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![BU of 7jkb by Molmil](/molmil-images/mine/7jkb) | 2xVH Fab | Descriptor: | Anti-Her2, Anti-lysozyme | Authors: | Lord, D.M, Zhou, Y.F. | Deposit date: | 2020-07-28 | Release date: | 2020-11-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Bringing the Heavy Chain to Light: Creating a Symmetric, Bivalent IgG-Like Bispecific. Antibodies, 9, 2020
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7E80
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![BU of 7e80 by Molmil](/molmil-images/mine/7e80) | Cryo-EM structure of the flagellar rod with hook and export apparatus from Salmonella | Descriptor: | Flagellar MS ring L1, Flagellar MS ring L2, Flagellar basal body rod protein FlgB, ... | Authors: | Tan, J.X, Chang, S.H, Wang, X.F, Xu, C.H, Zhou, Y, Zhang, X, Zhu, Y.Q. | Deposit date: | 2021-02-28 | Release date: | 2021-04-28 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.67 Å) | Cite: | Structural basis of assembly and torque transmission of the bacterial flagellar motor. Cell, 184, 2021
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7DHR
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![BU of 7dhr by Molmil](/molmil-images/mine/7dhr) | Cryo-EM structure of the full agonist isoprenaline-bound beta2 adrenergic receptor-Gs protein complex. | Descriptor: | Beta-2 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Yang, F, Ling, S.L, Zhou, Y.X, Zhang, Y.N, Lv, P, Liu, S.L, Fang, W, Sun, W.J, Hu, L.Y.A. | Deposit date: | 2020-11-17 | Release date: | 2020-12-16 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Different Conformational Responses of the beta2-Adrenergic Receptor-Gs Complex upon Binding of the Partial Agonist Salbutamol or the Full Agonist Isoprenaline Natl Sci Rev, 2020
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7E81
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![BU of 7e81 by Molmil](/molmil-images/mine/7e81) | Cryo-EM structure of the flagellar MS ring with FlgB-Dc loop and FliE-helix 1 from Salmonella | Descriptor: | Flagellar M-ring protein, FlgB-Dc loop, FliE helix 1 | Authors: | Tan, J.X, Chang, S.H, Wang, X.F, Xu, C.H, Zhou, Y, Zhang, X, Zhu, Y.Q. | Deposit date: | 2021-02-28 | Release date: | 2021-04-28 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural basis of assembly and torque transmission of the bacterial flagellar motor. Cell, 184, 2021
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7E82
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![BU of 7e82 by Molmil](/molmil-images/mine/7e82) | Cryo-EM structure of the flagellar rod with partial hook from Salmonella | Descriptor: | Flagellar MS ring L1, Flagellar MS ring L2, Flagellar basal body rod protein FlgB, ... | Authors: | Tan, J.X, Chang, S.H, Wang, X.F, Xu, C.H, Zhou, Y, Zhang, X, Zhu, Y.Q. | Deposit date: | 2021-02-28 | Release date: | 2021-04-28 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of assembly and torque transmission of the bacterial flagellar motor. Cell, 184, 2021
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8JBP
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![BU of 8jbp by Molmil](/molmil-images/mine/8jbp) | Crystal structure of triosephosphate isomerase from Leishmania orientalis at 1.45 angstroms resolution with an arsenic atom bound at Cys57 | Descriptor: | ARSENIC, Triosephosphate isomerase | Authors: | Kuaprasert, B, Leartsakulpanich, U, Riangrungroj, P, Pornthanakasem, W, Suginta, W, Robinson, R.C, Zhou, Y, Mungthin, M, Leelayoova, S, Saehlee, S, Choowongkomon, K. | Deposit date: | 2023-05-09 | Release date: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Leishmania orientalis triosephosphate isomerase crystal structure at 1.45 angstroms resolution and its potential specific inhibitors To be published
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7WI6
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![BU of 7wi6 by Molmil](/molmil-images/mine/7wi6) | Cryo-EM structure of LY341495/NAM-bound mGlu3 | Descriptor: | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 3 | Authors: | Fang, W, Yang, F, Xu, C.J, Ling, S.L, Lin, L, Zhou, Y.X, Sun, W.J, Wang, X.M, Liu, P, Rondard, P, Pan, S, Pin, J.P, Tian, C.L, Liu, J.F. | Deposit date: | 2022-01-03 | Release date: | 2022-03-16 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (3.71 Å) | Cite: | Structural basis of the activation of metabotropic glutamate receptor 3. Cell Res., 32, 2022
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7WIH
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![BU of 7wih by Molmil](/molmil-images/mine/7wih) | Cryo-EM structure of LY2794193-bound mGlu3 | Descriptor: | (1S,2S,4S,5R,6S)-2-amino-4-[(3-methoxybenzene-1-carbonyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 3 | Authors: | Fang, W, Yang, F, Xu, C.J, Ling, S.L, Lin, L, Zhou, Y.X, Sun, W.J, Wang, X.M, Liu, P, Rondard, P, Pan, S, Pin, J.P, Tian, C.L, Liu, J.F. | Deposit date: | 2022-01-03 | Release date: | 2022-03-16 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (3.68 Å) | Cite: | Structural basis of the activation of metabotropic glutamate receptor 3. Cell Res., 32, 2022
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7WI8
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![BU of 7wi8 by Molmil](/molmil-images/mine/7wi8) | Cryo-EM structure of inactive mGlu3 bound to LY341495 | Descriptor: | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 3 | Authors: | Fang, W, Yang, F, Xu, C.J, Ling, S.L, Lin, L, Zhou, Y.X, Sun, W.J, Wang, X.M, Liu, P, Rondard, P, Pan, S, Pin, J.P, Tian, C.L, Liu, J.F. | Deposit date: | 2022-01-03 | Release date: | 2022-03-16 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (4.17 Å) | Cite: | Structural basis of the activation of metabotropic glutamate receptor 3. Cell Res., 32, 2022
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7XIN
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![BU of 7xin by Molmil](/molmil-images/mine/7xin) | Crystal structure of DODC from Pseudomonas | Descriptor: | DOPA decarboxylase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Li, X, Zhou, Y.L, Liao, L.J, Liu, X.K, Liu, B, Guo, Y, Feng, Z, Sun, D.Y, Zeng, Z.X. | Deposit date: | 2022-04-13 | Release date: | 2023-04-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of DODC from Pseudomonas To Be Published
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7VUH
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![BU of 7vuh by Molmil](/molmil-images/mine/7vuh) | Cryo-EM structure of a class A orphan GPCR | Descriptor: | 3-chloranyl-N-[2-oxidanylidene-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Liu, Z.J, Hua, T, Zhou, Y.L, Wu, L.J. | Deposit date: | 2021-11-02 | Release date: | 2021-12-29 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Molecular insights into ligand recognition and G protein coupling of the neuromodulatory orphan receptor GPR139. Cell Res., 32, 2022
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7VUJ
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![BU of 7vuj by Molmil](/molmil-images/mine/7vuj) | Cryo-EM structure of a class A orphan GPCR | Descriptor: | 3-chloranyl-N-[2-oxidanylidene-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide, GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Liu, Z.J, Hua, T, Zhou, Y.L, Wu, L.J. | Deposit date: | 2021-11-02 | Release date: | 2021-12-29 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Molecular insights into ligand recognition and G protein coupling of the neuromodulatory orphan receptor GPR139. Cell Res., 32, 2022
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7VUI
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![BU of 7vui by Molmil](/molmil-images/mine/7vui) | Cryo-EM structure of a class A orphan GPCR | Descriptor: | 3-chloranyl-N-[2-oxidanylidene-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide, Chimera of Endo-1,4-beta-xylanase and Probable G-protein coupled receptor 139, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Liu, Z.J, Hua, T, Zhou, Y.L, Wu, L.J. | Deposit date: | 2021-11-02 | Release date: | 2021-12-29 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular insights into ligand recognition and G protein coupling of the neuromodulatory orphan receptor GPR139. Cell Res., 32, 2022
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