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PDB: 107 件

4GWG
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Crystal Structure Analysis of 6-phosphogluconate dehydrogenase apo-form
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-phosphogluconate dehydrogenase, decarboxylating
著者He, C, Zhou, L, Zhang, L.
登録日2012-09-03
公開日2012-11-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.3907 Å)
主引用文献Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth.
Cancer Cell, 22, 2012
4GPZ
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Crystal structure of human B type phosphoglycerate mutase H11 phosphorylated form
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Phosphoglycerate mutase 1
著者He, C, Zhou, L, Zhang, L.
登録日2012-08-22
公開日2013-05-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation.
Nat Commun, 4, 2013
4GWK
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Crystal structure of 6-phosphogluconate dehydrogenase complexed with 3-phosphoglyceric acid
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-PHOSPHOGLYCERIC ACID, 6-phosphogluconate dehydrogenase, ...
著者He, C, Zhou, L, Zhang, L.
登録日2012-09-03
公開日2012-11-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.534 Å)
主引用文献Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth.
Cancer Cell, 22, 2012
3L1L
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Structure of Arg-bound Escherichia coli AdiC
分子名称: ARGININE, Arginine/agmatine antiporter, nonyl beta-D-glucopyranoside
著者Gao, X, Zhou, L, Shi, Y.
登録日2009-12-13
公開日2010-02-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.002 Å)
主引用文献Mechanism of substrate recognition and transport by an amino acid antiporter
Nature, 463, 2010
4JNF
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Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP
分子名称: Hsp70 CHAPERONE DnaK
著者Qi, R, Sarbeng, E.B, Liu, Q, Le, K.Q, Xu, X, Xu, H, Yang, J, Wong, J.L, Vorvis, C, Hendrickson, W.A, Zhou, L, Liu, Q.
登録日2013-03-15
公開日2013-05-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.621 Å)
主引用文献Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP.
Nat.Struct.Mol.Biol., 20, 2013
6TT7
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Ovine ATP synthase 1a state
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ADENOSINE-5'-DIPHOSPHATE, ATP synthase F(0) complex subunit C1, ...
著者Pinke, G, Zhou, L, Sazanov, L.A.
登録日2019-12-23
公開日2020-09-23
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of the entire mammalian F-type ATP synthase.
Nat.Struct.Mol.Biol., 27, 2020
4HBN
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Crystal structure of the human HCN4 channel C-terminus carrying the S672R mutation
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, PHOSPHATE ION, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
著者Xu, X, Marni, F, Wu, X, Su, Z, Musayev, F, Shrestha, S, Xie, C, Gao, W, Liu, Q, Zhou, L.
登録日2012-09-28
公開日2013-01-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Local and Global Interpretations of a Disease-Causing Mutation near the Ligand Entry Path in Hyperpolarization-Activated cAMP-Gated Channel.
Structure, 20, 2012
1G55
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Structure of human DNMT2, an enigmatic DNA methyltransferase homologue
分子名称: BETA-MERCAPTOETHANOL, DNA CYTOSINE METHYLTRANSFERASE DNMT2, GLYCEROL, ...
著者Dong, A, Yoder, J.A, Zhang, X, Zhou, L, Bestor, T.H, Cheng, X.
登録日2000-10-30
公開日2001-01-17
最終更新日2018-06-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA.
Nucleic Acids Res., 29, 2001
3OTF
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Structural basis for the cAMP-dependent gating in human HCN4 channel
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
著者Xu, X, Vysotskaya, Z.V, Liu, Q, Zhou, L.
登録日2010-09-11
公開日2010-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the cAMP-dependent gating in the human HCN4 channel.
J.Biol.Chem., 285, 2010
7XBA
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Glutathione S-transferase bound with a covalent inhibitor
分子名称: 3-[3-[[2-[5-[(3,5-dimethyl-4-nitro-pyrazol-1-yl)methyl]furan-2-yl]-5-(methylcarbamoyl)benzimidazol-1-yl]methyl]azetidin-1-yl]sulfonylbenzenesulfonic acid, GLUTATHIONE, Glutathione S-transferase P
著者Jiang, L.L, Zhou, L.
登録日2022-03-21
公開日2023-09-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Glutathione S-transferase bound with a covalent inhibitor
To Be Published
7XB8
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Phosphoglycerate mutase 1 complexed with a covalent inhibitor
分子名称: 4-(cyclopenten-1-yl)-2-[(3-sulfophenyl)sulfonylamino]benzoic acid, CHLORIDE ION, Phosphoglycerate mutase 1
著者Jiang, L.L, Zhou, L.
登録日2022-03-21
公開日2023-09-27
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Phosphoglycerate mutase 1 complexed with a covalent inhibitor
To Be Published
7XB9
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Phosphoglycerate mutase 1 complexed with a covalent inhibitor
分子名称: 3-[[5-(cyclopenten-1-yl)-2-methoxycarbonyl-phenyl]sulfamoyl]benzenesulfonic acid, CHLORIDE ION, Phosphoglycerate mutase 1
著者Jiang, L.L, Zhou, L.
登録日2022-03-21
公開日2023-09-27
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Phosphoglycerate mutase 1 complexed with a covalent inhibitor
To Be Published
7XB7
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Phosphoglycerate mutase 1 complexed with a covalent inhibitor
分子名称: 3-[[5-(cyclopenten-1-yl)-2-(methylcarbamoyl)phenyl]sulfamoyl]benzenesulfonic acid, CHLORIDE ION, Phosphoglycerate mutase 1
著者Jiang, L.L, Zhou, L.
登録日2022-03-21
公開日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Phosphoglycerate mutase 1 complexed with a covalent inhibitor
To Be Published
1F3L
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CRYSTAL STRUCTURE OF THE CONSERVED CORE OF PROTEIN ARGININE METHYLTRANSFERASE PRMT3
分子名称: PROTEIN ARGININE METHYLTRANSFERASE PRMT3, S-ADENOSYL-L-HOMOCYSTEINE
著者Zhang, X, Zhou, L, Cheng, X.
登録日2000-06-05
公開日2001-03-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Crystal structure of the conserved core of protein arginine methyltransferase PRMT3.
EMBO J., 19, 2000
2BW3
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Three-dimensional structure of the Hermes DNA transposase
分子名称: TRANSPOSASE
著者Hickman, A.B, Perez, Z.N, Zhou, L, Musingarimi, P, Ghirlando, R, Hinshaw, J.E, Craig, N.L, Dyda, F.
登録日2005-07-11
公開日2005-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular Architecture of a Eukaryotic DNA Transposase
Nat.Struct.Mol.Biol., 12, 2005
1Q0S
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Binary Structure of T4DAM with AdoHcy
分子名称: DNA adenine methylase, S-ADENOSYL-L-HOMOCYSTEINE
著者Yang, Z, Horton, J.R, Zhou, L, Zhang, X.J, Dong, A, Zhang, X, Schlagman, S.L, Kossykh, V, Hattman, S, Cheng, X.
登録日2003-07-17
公開日2003-09-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the bacteriophage T4 DNA adenine methyltransferase
Nat.Struct.Biol., 10, 2003
1Q0T
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Ternary Structure of T4DAM with AdoHcy and DNA
分子名称: 5'-D(*AP*CP*AP*GP*GP*AP*TP*CP*CP*TP*GP*T)-3', DNA adenine methylase, IODIDE ION, ...
著者Yang, Z, Horton, J.R, Zhou, L, Zhang, X.J, Dong, A, Zhang, X, Schlagman, S.L, Kossykh, V, Hattman, S, Cheng, X.
登録日2003-07-17
公開日2003-09-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of the bacteriophage T4 DNA adenine methyltransferase
Nat.Struct.Biol., 10, 2003
8J0I
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Aldo-keto reductase KmAKR
分子名称: NADPH-dependent alpha-keto amide reductase, SODIUM ION
著者Xu, S.Y, Zhou, L, Xu, Y, Wang, Y.J, Zheng, Y.G.
登録日2023-04-11
公開日2024-04-17
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Aldo-keto reductase KmAKR from Kluyveromyces marxianus
To Be Published
6ZA9
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Fo domain of Ovine ATP synthase
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ATP synthase F(0) complex subunit C1, mitochondrial, ...
著者Pinke, G, Zhou, L, Sazanov, L.A.
登録日2020-06-05
公開日2020-09-23
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.76 Å)
主引用文献Cryo-EM structure of the entire mammalian F-type ATP synthase.
Nat.Struct.Mol.Biol., 27, 2020
3WSQ
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Structure of HER2 with an Fab
分子名称: Antibody Heavy Chain, Antibody Light Chain, Receptor tyrosine-protein kinase erbB-2
著者Fu, W.Y, Wang, Y.X, Zhou, L.J.
登録日2014-03-20
公開日2015-03-25
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Insights into HER2 signaling from step-by-step optimization of anti-HER2 antibodies.
MAbs, 6, 2014
6X89
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Vigna radiata mitochondrial complex I*
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
著者Letts, J.A, Maldonado, M, Padavannil, A, Zhou, L, Guo, F.
登録日2020-06-01
公開日2020-09-02
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Atomic structure of a mitochondrial complex I intermediate from vascular plants.
Elife, 9, 2020
8HGK
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Crystal structure of human ClpP in complex with ZK53
分子名称: 4-[[3,5-bis(fluoranyl)phenyl]methyl]-N-[(4-bromophenyl)methyl]piperazine-1-carboxamide, ATP-dependent Clp protease proteolytic subunit, mitochondrial, ...
著者Yang, C.-G, Gan, J.H, Zhou, L.-L.
登録日2022-11-14
公開日2023-09-27
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma.
Nat Commun, 14, 2023
8FEQ
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16mer self-complementary duplex RNA with two separated s(2)U:s(2)U pairs
分子名称: CALCIUM ION, RNA 16mer with two separated s(2)U
著者Fang, Z, Zhou, L, Szostak, J.W.
登録日2022-12-06
公開日2024-01-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Unusual Base Pair between Two 2-Thiouridines and Its Implication for Nonenzymatic RNA Copying.
J.Am.Chem.Soc., 146, 2024
8FER
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16mer self-complementary duplex RNA with two continuous s(2)U:s(2)U pairs
分子名称: RNA 16mer with two continuous s(2)U
著者Fang, Z, Zhou, L, Szostak, J.W.
登録日2022-12-06
公開日2024-01-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Unusual Base Pair between Two 2-Thiouridines and Its Implication for Nonenzymatic RNA Copying.
J.Am.Chem.Soc., 146, 2024
3QAU
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3-Hydroxy-3-MethylGlutaryl-Coenzyme A Reductase from Streptococcus pneumoniae
分子名称: 3-hydroxy-3-methylglutaryl-coenzyme a reductase, GLYCEROL, SODIUM ION, ...
著者Zhang, L, Feng, L, Zhou, L, Gui, J, Wan, J.
登録日2011-01-11
公開日2011-01-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献3-Hydroxy-3-MethylGlutaryl-Coenzyme A Reductase from Streptococcus pneumoniae
To be Published

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