3CVK
 
 | | Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor | | 分子名称: | N-{3-[1-(3,3-Dimethyl-butyl)-4-hydroxy-2-oxo-1,2,4a,5,6,7-hexahydro-pyrrolo[1,2-b]pyridazin-3-yl]-1,1-dioxo-1,2-dihydro -1lambda6-benzo[1,2,4]thiadiazin-7-yl}-methanesulfonamide, RNA-directed RNA polymerase | | 著者 | Zhao, Q, Showalter, R.E, Han, Q, Kissinger, C.R. | | 登録日 | 2008-04-18 | | 公開日 | 2009-04-21 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Hexahydro-pyrrolo- and hexahydro-1H-pyrido[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase.
Bioorg.Med.Chem.Lett., 18, 2008
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8J7N
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8J7P
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1YDU
 | | Solution NMR structure of At5g01610, an Arabidopsis thaliana protein containing DUF538 domain | | 分子名称: | At5g01610 | | 著者 | Zhao, Q, Cornilescu, C.C, Lee, M.S, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2004-12-26 | | 公開日 | 2005-02-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structure of At5g01610, an Arabidopsis thaliana protein containing DUF538 domain
To be Published
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4NE1
 | | Human MHF1 MHF2 DNA complexes | | 分子名称: | Centromere protein S, Centromere protein X, DNA (26-MER) | | 著者 | Zhao, Q, Saro, D, Sachpatzidis, A, Sung, P, Xiong, Y. | | 登録日 | 2013-10-28 | | 公開日 | 2014-01-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (6.499 Å) | | 主引用文献 | The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
Nat Commun, 5, 2014
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4NDY
 | | Human MHF1-MHF2 DNA complex | | 分子名称: | Centromere protein S, Centromere protein X, DNA (26-MER) | | 著者 | Zhao, Q, Saro, D, Sachpatzidis, A, Sung, P, Xiong, Y. | | 登録日 | 2013-10-28 | | 公開日 | 2014-01-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (6.999 Å) | | 主引用文献 | The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
Nat Commun, 5, 2014
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3D23
 | | Main protease of HCoV-HKU1 | | 分子名称: | 3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE | | 著者 | Zhao, Q, Chen, C, Li, S, Zou, Y. | | 登録日 | 2008-05-07 | | 公開日 | 2008-09-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of the main protease from a global infectious human coronavirus, HCoV-HKU1.
J.Virol., 82, 2008
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4NE5
 | | Human MHF1-MHF2 complex | | 分子名称: | Centromere protein S, Centromere protein X | | 著者 | Zhao, Q, Saro, D, Sachpatzidis, A, Sung, P, Xiong, Y. | | 登録日 | 2013-10-28 | | 公開日 | 2013-12-25 | | 最終更新日 | 2014-02-12 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
Nat Commun, 5, 2014
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4NE6
 | | Human MHF1-MHF2 complex | | 分子名称: | Centromere protein S, Centromere protein X | | 著者 | Zhao, Q, Saro, D, Sachpatzidis, A, Sung, P, Xiong, Y. | | 登録日 | 2013-10-28 | | 公開日 | 2013-12-25 | | 最終更新日 | 2014-02-12 | | 実験手法 | X-RAY DIFFRACTION (2.1001 Å) | | 主引用文献 | The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
Nat Commun, 5, 2014
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4NE3
 | | Human MHF1-MHF2 complex | | 分子名称: | Centromere protein S, Centromere protein X | | 著者 | Zhao, Q, Saro, D, Sachpatzidis, A, Sung, P, Xiong, Y. | | 登録日 | 2013-10-28 | | 公開日 | 2013-12-25 | | 最終更新日 | 2014-02-12 | | 実験手法 | X-RAY DIFFRACTION (1.8007 Å) | | 主引用文献 | The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
Nat Commun, 5, 2014
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2HEM
 | | NMR structure and Mg2+ binding of an RNA segment that underlies the L7/L12 stalk in the E.coli 50S ribosomal subunit. | | 分子名称: | 5'-R(P*GP*GP*GP*AP*AP*GP*GP*CP*GP*CP*UP*UP*CP*GP*GP*CP*GP*UP*CP*GP*GP*CP*CP*C)-3' | | 著者 | Zhao, Q, Nagaswamy, U, Lee, H, Xia, Y, Gao, X, Fox, G. | | 登録日 | 2006-06-21 | | 公開日 | 2006-09-12 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure and Mg2+ binding of an RNA segment that underlies the L7/L12 stalk in the E.coli 50S ribosomal subunit
Nucleic Acids Res., 33, 2005
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2NS2
 | | Crystal Structure of Spindlin1 | | 分子名称: | PHOSPHATE ION, Spindlin-1 | | 著者 | Zhao, Q, Qin, L, Jiang, F, Wu, B, Yue, W, Xu, F, Rong, Z, Yuan, H, Xie, X, Gao, Y, Bai, C, Bartlam, M. | | 登録日 | 2006-11-02 | | 公開日 | 2006-11-28 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of human spindlin1. Tandem tudor-like domains for cell cycle regulation
J.Biol.Chem., 282, 2007
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8KF4
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8KF1
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8KEW
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8KF6
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8KF5
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8KF3
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7YS6
 | | Cryo-EM structure of the Serotonin 6 (5-HT6) receptor-DNGs-scFv16 complex | | 分子名称: | 5-hydroxytryptamine receptor 6, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Zhao, Q.Y, Wang, Y.F, He, L, Wang, S, Cong, Y. | | 登録日 | 2022-08-11 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural insights into constitutive activity of 5-HT 6 receptor.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8K8K
 | | Structure of Klebsiella pneumonia ModA | | 分子名称: | Molybdate transporter periplasmic protein | | 著者 | Zhao, Q, Bartlam, M. | | 登録日 | 2023-07-31 | | 公開日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structural analysis of molybdate binding protein ModA from Klebsiella pneumoniae.
Biochem.Biophys.Res.Commun., 681, 2023
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8K8L
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8K7N
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7F5W
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7X84
 | | Cryo-EM structure of the TMEM106B fibril from Parkinson's disease dementia | | 分子名称: | Transmembrane protein 106B | | 著者 | Zhao, Q.Y, Xia, W.C, Fan, Y, Sun, Y.P, Tao, Y.Q, Liu, C. | | 登録日 | 2022-03-11 | | 公開日 | 2022-06-15 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Generic amyloid fibrillation of TMEM106B in patient with Parkinson's disease dementia and normal elders.
Cell Res., 32, 2022
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4LVF
 | | Fragment-based Identification of Amides Derived From trans-2-(Pyridin-3-yl)cyclopropanecarboxylic Acid as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT) | | 分子名称: | (1S,2S)-2-phenyl-N-(pyridin-4-yl)cyclopropanecarboxamide, 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, ... | | 著者 | Giannetti, A.M, Zheng, X, Skelton, N, Wang, W, Bravo, B, Feng, Y, Gunzner-Toste, J, Ho, Y, Hua, R, Wang, C, Zhao, Q, Liederer, B.M, Liu, Y, O'Brien, T, Oeh, J, Sampath, D, Shen, Y, Wang, L, Wu, H, Xiao, Y, Yuen, P, Zak, M, Zhao, G, Dragovich, P.S. | | 登録日 | 2013-07-26 | | 公開日 | 2013-09-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).
Bioorg.Med.Chem.Lett., 23, 2013
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