7X84

Cryo-EM structure of the TMEM106B fibril from Parkinson's disease dementia

Summary for 7X84

• Entry DOI: 10.2210/pdb7x84/pdb
• EMDB information: 33055
• Descriptor: Transmembrane protein 106B (1 entity in total)
• Functional Keywords: protein fibril, amyloid
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 46508.04

Authors

Zhao, Q.Y.,Xia, W.C.,Fan, Y.,Sun, Y.P.,Tao, Y.Q.,Liu, C. (deposition date: 2022-03-11, release date: 2022-06-15)

• Primary citation: Fan, Y.,Zhao, Q.,Xia, W.,Tao, Y.,Yu, W.,Chen, M.,Liu, Y.,Zhao, J.,Shen, Y.,Sun, Y.,Si, C.,Zhang, S.,Zhang, Y.,Li, W.,Liu, C.,Wang, J.,Li, D.; Generic amyloid fibrillation of TMEM106B in patient with Parkinson's disease dementia and normal elders.; Cell Res., 32:585-588, 2022; PubMed: 35477998; DOI: 10.1038/s41422-022-00665-3

Experimental method

ELECTRON MICROSCOPY (3 Å)