7X84

Cryo-EM structure of the TMEM106B fibril from Parkinson's disease dementia

Summary for 7X84

Entry DOI	10.2210/pdb7x84/pdb
EMDB information	33055
Descriptor	Transmembrane protein 106B (1 entity in total)
Functional Keywords	protein fibril, amyloid
Biological source	Homo sapiens (human)
Total number of polymer chains	3
Total formula weight	46508.04
Authors	Zhao, Q.Y.,Xia, W.C.,Fan, Y.,Sun, Y.P.,Tao, Y.Q.,Liu, C. (deposition date: 2022-03-11, release date: 2022-06-15, Last modification date: 2024-11-06)
Primary citation	Fan, Y.,Zhao, Q.,Xia, W.,Tao, Y.,Yu, W.,Chen, M.,Liu, Y.,Zhao, J.,Shen, Y.,Sun, Y.,Si, C.,Zhang, S.,Zhang, Y.,Li, W.,Liu, C.,Wang, J.,Li, D. Generic amyloid fibrillation of TMEM106B in patient with Parkinson's disease dementia and normal elders. Cell Res., 32:585-588, 2022 Cited by PubMed: 35477998 DOI: 10.1038/s41422-022-00665-3 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3 Å)

Structure validation