4NE1

Human MHF1 MHF2 DNA complexes

Summary for 4NE1

Related4NDY
DescriptorDNA (26-MER), Centromere protein S, Centromere protein X, ... (4 entities in total)
Functional Keywordshistone fold, dna repair, genome maintenance, fanconi anemia, fancm, nucleus, dna binding protein-dna complex, dna binding protein/dna
Biological sourceHomo sapiens (human)
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Total number of polymer chains48
Total molecular weight473664.81
Authors
Zhao, Q.,Saro, D.,Sachpatzidis, A.,Sung, P.,Xiong, Y. (deposition date: 2013-10-28, release date: 2014-01-22, Last modification date: 2020-01-29)
Primary citation
Zhao, Q.,Saro, D.,Sachpatzidis, A.,Singh, T.R.,Schlingman, D.,Zheng, X.F.,Mack, A.,Tsai, M.S.,Mochrie, S.,Regan, L.,Meetei, A.R.,Sung, P.,Xiong, Y.
The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
Nat Commun, 5:2987-2987, 2014
PubMed: 24390579 (PDB entries with the same primary citation)
DOI: 10.1038/ncomms3987
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (6.499 Å)
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Structure validation

RfreeRamachandran outliersSidechain outliers 0.320 0.0% 8.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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171916
PDB entries from 2020-12-02