Human MHF1-MHF2 complex

Summary for 4NE3

Related4NE1 4NDY 4NE5 4NE6
DescriptorCentromere protein S, Centromere protein X (3 entities in total)
Functional Keywordshistone fold, dna repair, genome maintenance, fanconi anemia, fancm, dna binding protein
Biological sourceHomo sapiens (human)
Cellular locationNucleus Q8N2Z9 A8MT69
Total number of polymer chains2
Total molecular weight19185.68
Zhao, Q.,Saro, D.,Sachpatzidis, A.,Sung, P.,Xiong, Y. (deposition date: 2013-10-28, release date: 2013-12-25, Last modification date: 2014-02-12)
Primary citation
Zhao, Q.,Saro, D.,Sachpatzidis, A.,Singh, T.R.,Schlingman, D.,Zheng, X.F.,Mack, A.,Tsai, M.S.,Mochrie, S.,Regan, L.,Meetei, A.R.,Sung, P.,Xiong, Y.
The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
Nat Commun, 5:2987-2987, 2014
PubMed: 24390579 (PDB entries with the same primary citation)
DOI: 10.1038/ncomms3987
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.24813 0.6% 2.1% 13.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-12-02