4M6Q
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![BU of 4m6q by Molmil](/molmil-images/mine/4m6q) | Identification of Amides Derived From 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic Acid as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT) | Descriptor: | 1-(5-O-phosphono-beta-D-ribofuranosyl)-N-(4-{[3-(trifluoromethyl)phenyl]sulfonyl}benzyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION, ... | Authors: | Giannetti, A.M, Zheng, X, Skelton, N, Wang, W, Bravo, B, Feng, Y, Gunzner-Toste, J, Ho, Y, Hua, R, Wang, C, Zhao, Q, Liederer, B.M, Liu, Y, O'Brien, T, Oeh, J, Sampath, D, Shen, Y, Wang, L, Wu, H, Xiao, Y, Yuen, P, Zak, M, Zhao, G, Dragovich, P.S. | Deposit date: | 2013-08-10 | Release date: | 2013-09-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.406 Å) | Cite: | Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). Bioorg.Med.Chem.Lett., 23, 2013
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4M6P
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![BU of 4m6p by Molmil](/molmil-images/mine/4m6p) | Identification of Amides Derived From 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic Acid as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT) | Descriptor: | N-[4-(phenylsulfonyl)benzyl]-2H-pyrazolo[3,4-b]pyridine-5-carboxamide, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION | Authors: | Giannetti, A.M, Zheng, X, Skelton, N, Wang, W, Bravo, B, Feng, Y, Gunzner-Toste, J, Ho, Y, Hua, R, Wang, C, Zhao, Q, Liederer, B.M, Liu, Y, O'Brien, T, Oeh, J, Sampath, D, Shen, Y, Wang, L, Wu, H, Xiao, Y, Yuen, P, Zak, M, Zhao, G, Dragovich, P.S. | Deposit date: | 2013-08-10 | Release date: | 2013-09-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). Bioorg.Med.Chem.Lett., 23, 2013
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4LVB
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![BU of 4lvb by Molmil](/molmil-images/mine/4lvb) | Fragment-based Identification of Amides Derived From trans-2-(Pyridin-3-yl)cyclopropanecarboxylic Acid as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT) | Descriptor: | 1,2-ETHANEDIOL, N-[4-(acetylamino)phenyl]cyclopropanecarboxamide, Nicotinamide phosphoribosyltransferase, ... | Authors: | Giannetti, A.M, Zheng, X, Skelton, N, Wang, W, Bravo, B, Feng, Y, Gunzner-Toste, J, Ho, Y, Hua, R, Wang, C, Zhao, Q, Liederer, B.M, Liu, Y, O'Brien, T, Oeh, J, Sampath, D, Shen, Y, Wang, L, Wu, H, Xiao, Y, Yuen, P, Zak, M, Zhao, G, Dragovich, P.S. | Deposit date: | 2013-07-26 | Release date: | 2013-09-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.836 Å) | Cite: | Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). Bioorg.Med.Chem.Lett., 23, 2013
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6SKM
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![BU of 6skm by Molmil](/molmil-images/mine/6skm) | Structure of the native full-length HIV-1 capsid protein A92E in helical assembly (-13,12) | Descriptor: | Gag protein | Authors: | Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P. | Deposit date: | 2019-08-16 | Release date: | 2020-08-26 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A. Nat.Struct.Mol.Biol., 27, 2020
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6SLQ
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![BU of 6slq by Molmil](/molmil-images/mine/6slq) | Structure of the native full-length HIV-1 capsid protein A92E in helical assembly (-12,11) | Descriptor: | Gag protein | Authors: | Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P. | Deposit date: | 2019-08-20 | Release date: | 2020-09-09 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A. Nat.Struct.Mol.Biol., 27, 2020
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6SLU
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![BU of 6slu by Molmil](/molmil-images/mine/6slu) | Structure of the native full-length HIV-1 capsid protein A92E in helical assembly (-13,11) | Descriptor: | Gag protein | Authors: | Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P. | Deposit date: | 2019-08-20 | Release date: | 2020-09-09 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A. Nat.Struct.Mol.Biol., 27, 2020
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6SMU
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![BU of 6smu by Molmil](/molmil-images/mine/6smu) | Structure of the native full-length HIV-1 capsid protein in helical assembly (-13,12) | Descriptor: | Gag protein | Authors: | Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P. | Deposit date: | 2019-08-22 | Release date: | 2020-09-09 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A. Nat.Struct.Mol.Biol., 27, 2020
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1TV4
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![BU of 1tv4 by Molmil](/molmil-images/mine/1tv4) | Crystal structure of the sulfite MtmB complex | Descriptor: | 3-METHYL-5-SULFO-PYRROLIDINE-2-CARBOXYLIC ACID, Monomethylamine methyltransferase mtmB1, SULFATE ION | Authors: | Hao, B, Zhao, G, Kang, P.T, Soares, J.A, Ferguson, T.K, Gallucci, J, Krzycki, J.A, Chan, M.K. | Deposit date: | 2004-06-26 | Release date: | 2004-10-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Reactivity and chemical synthesis of L-pyrrolysine- the 22(nd) genetically encoded amino acid Chem.Biol., 11, 2004
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6SKK
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![BU of 6skk by Molmil](/molmil-images/mine/6skk) | Structure of the native full-length HIV-1 capsid protein in helical assembly (-13,8) | Descriptor: | capsid protein | Authors: | Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P. | Deposit date: | 2019-08-15 | Release date: | 2020-08-26 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A. Nat.Struct.Mol.Biol., 27, 2020
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6JOB
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![BU of 6job by Molmil](/molmil-images/mine/6job) | Ferritin variant with "GMG" motif | Descriptor: | Ferritin heavy chain | Authors: | Zheng, B.W, Zhou, K, Zhang, T, Lv, C, Wang, H, Zhao, G. | Deposit date: | 2019-03-20 | Release date: | 2020-03-25 | Last modified: | 2024-03-27 | Method: | SOLUTION SCATTERING (2.93 Å), X-RAY DIFFRACTION | Cite: | Self-assembly of protein nanocage into designed 2D and 3D networks by grafting amyloidogenic motifs on the exterior surfaces. To Be Published
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6IPC
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![BU of 6ipc by Molmil](/molmil-images/mine/6ipc) | Non-native human ferritin 8-mer | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Ferritin heavy chain | Authors: | Zang, J.C, Chen, H, Zhao, G. | Deposit date: | 2018-11-03 | Release date: | 2019-03-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (4.443 Å) | Cite: | Disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages. Nat Commun, 10, 2019
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6J7G
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![BU of 6j7g by Molmil](/molmil-images/mine/6j7g) | |
6J4A
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![BU of 6j4a by Molmil](/molmil-images/mine/6j4a) | |
6IPO
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![BU of 6ipo by Molmil](/molmil-images/mine/6ipo) | Ferritin mutant C90A/C102A/C130A/D144C | Descriptor: | Ferritin heavy chain, MAGNESIUM ION | Authors: | Zang, J, Chen, H, Zhang, X, Zhao, G. | Deposit date: | 2018-11-03 | Release date: | 2019-03-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.998 Å) | Cite: | Disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages. Nat Commun, 10, 2019
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1TV3
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![BU of 1tv3 by Molmil](/molmil-images/mine/1tv3) | Crystal structure of the N-methyl-hydroxylamine MtmB complex | Descriptor: | 5-(HYDROXY-METHYL-AMINO)-3-METHYL-PYRROLIDINE-2-CARBOXYLIC ACID, Monomethylamine methyltransferase mtmB1 | Authors: | Hao, B, Zhao, G, Kang, P.T, Soares, J.A, Ferguson, T.K, Gallucci, J, Krzycki, J.A, Chan, M.K. | Deposit date: | 2004-06-26 | Release date: | 2004-10-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Reactivity and chemical synthesis of L-pyrrolysine- the 22(nd) genetically encoded amino acid Chem.Biol., 11, 2004
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6J4M
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![BU of 6j4m by Molmil](/molmil-images/mine/6j4m) | Thermal treated soybean seed H-2 ferritin | Descriptor: | Ferritin, MAGNESIUM ION | Authors: | Zhang, X, Zang, J, Chen, H, Zhou, K, Zhao, G. | Deposit date: | 2019-01-09 | Release date: | 2019-09-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.598 Å) | Cite: | Thermostability of protein nanocages: the effect of natural extra peptide on the exterior surface. Rsc Adv, 9, 2019
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1TV2
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![BU of 1tv2 by Molmil](/molmil-images/mine/1tv2) | Crystal structure of the hydroxylamine MtmB complex | Descriptor: | 5-HYDROXYAMINO-3-METHYL-PYRROLIDINE-2-CARBOXYLIC ACID, Monomethylamine methyltransferase mtmB1 | Authors: | Hao, B, Zhao, G, Kang, P.T, Soares, J.A, Ferguson, T.K, Gallucci, J, Krzycki, J.A, Chan, M.K. | Deposit date: | 2004-06-26 | Release date: | 2004-10-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Reactivity and chemical synthesis of L-pyrrolysine- the 22(nd) genetically encoded amino acid Chem.Biol., 11, 2004
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6J4J
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![BU of 6j4j by Molmil](/molmil-images/mine/6j4j) | soybean seed H-2 ferritin | Descriptor: | Ferritin, MAGNESIUM ION | Authors: | Zhang, X, Zang, J, Chen, H, Zhao, G. | Deposit date: | 2019-01-09 | Release date: | 2019-09-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.101 Å) | Cite: | Thermostability of protein nanocages: the effect of natural extra peptide on the exterior surface. Rsc Adv, 9, 2019
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6KH0
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![BU of 6kh0 by Molmil](/molmil-images/mine/6kh0) | |
7CPC
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![BU of 7cpc by Molmil](/molmil-images/mine/7cpc) | |
7CPI
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![BU of 7cpi by Molmil](/molmil-images/mine/7cpi) | |
6CMO
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![BU of 6cmo by Molmil](/molmil-images/mine/6cmo) | Rhodopsin-Gi complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab Heavy chain, Fab light chain, ... | Authors: | Kang, Y, Kuybeda, O, de Waal, P.W, Mukherjee, S, Van Eps, N, Dutka, P, Zhou, X.E, Bartesaghi, A, Erramilli, S, Morizumi, T, Gu, X, Yin, Y, Liu, P, Jiang, Y, Meng, X, Zhao, G, Melcher, K, Earnst, O.P, Kossiakoff, A.A, Subramaniam, S, Xu, H.E. | Deposit date: | 2018-03-05 | Release date: | 2018-06-20 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Cryo-EM structure of human rhodopsin bound to an inhibitory G protein. Nature, 558, 2018
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2A89
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![BU of 2a89 by Molmil](/molmil-images/mine/2a89) | Monomeric Sarcosine Oxidase: Structure of a covalently flavinylated amine oxidizing enzyme | Descriptor: | (N5,C4A)-(ALPHA-HYDROXY-PROPANO)-3,4,4A,5-TETRAHYDRO-FLAVIN-ADENINE DINUCLEOTIDE, CHLORIDE ION, Monomeric sarcosine oxidase, ... | Authors: | Chen, Z.-W, Zhao, G, Martinovic, S, Jorns, M.S, Mathews, F.S. | Deposit date: | 2005-07-07 | Release date: | 2006-01-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure of the sodium borohydride-reduced N-(cyclopropyl)glycine adduct of the flavoenzyme monomeric sarcosine oxidase. Biochemistry, 44, 2005
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7LHG
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![BU of 7lhg by Molmil](/molmil-images/mine/7lhg) | Cryo-EM structure of E. coli P pilus tip assembly intermediate PapC-PapD-PapK-PapG in the first conformation | Descriptor: | Chaperone protein PapD, Fimbrial adapter PapK, P fimbria tip G-adhesin PapG-II, ... | Authors: | Du, M, Yuan, Z, Werneburg, G, Henderson, N, Chauhan, H, Kovach, A, Zhao, G, Johl, J, Li, H, Thanassi, D. | Deposit date: | 2021-01-23 | Release date: | 2021-08-11 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Processive dynamics of the usher assembly platform during uropathogenic Escherichia coli P pilus biogenesis. Nat Commun, 12, 2021
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7LHH
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![BU of 7lhh by Molmil](/molmil-images/mine/7lhh) | Cryo-EM structure of E. coli P pilus tip assembly intermediate PapC-PapD-PapK-PapG in the second conformation | Descriptor: | Chaperone protein PapD, Fimbrial adapter PapK, P fimbria tip G-adhesin PapG-II, ... | Authors: | Du, M, Yuan, Z, Werneburg, G, Henderson, N, Chauhan, H, Kovach, A, Zhao, G, Johl, J, Li, H, Thanassi, D. | Deposit date: | 2021-01-23 | Release date: | 2021-08-11 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (7.2 Å) | Cite: | Processive dynamics of the usher assembly platform during uropathogenic Escherichia coli P pilus biogenesis. Nat Commun, 12, 2021
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