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PDB: 824 件
1MVX
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structure of the SET domain histone lysine methyltransferase Clr4
分子名称: CRYPTIC LOCI REGULATOR 4, NICKEL (II) ION, SULFATE ION, ...
著者Min, J.R, Zhang, X, Cheng, X.D, Grewal, S.I.S, Xu, R.-M.
登録日2002-09-26
公開日2002-10-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the SET domain histone lysine methyltransferase Clr4.
Nat.Struct.Biol., 9, 2002
1MVH
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structure of the SET domain histone lysine methyltransferase Clr4
分子名称: Cryptic loci regulator 4, NICKEL (II) ION, SULFATE ION, ...
著者Min, J.R, Zhang, X, Cheng, X.D, Grewal, S.I.S, Xu, R.-M.
登録日2002-09-25
公開日2002-10-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the SET domain histone lysine methyltransferase Clr4.
Nat.Struct.Biol., 9, 2002
2L6K
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Solution Structure of a Nonphosphorylated Peptide Recognizing Domain
分子名称: Tensin-like C1 domain-containing phosphatase
著者Dai, K, Liao, S, Zhang, J, Zhang, X, Tu, X.
登録日2010-11-22
公開日2011-10-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of Tensin2 SH2 domain and its phosphotyrosine-independent interaction with DLC-1
Plos One, 6, 2011
6IPO
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Ferritin mutant C90A/C102A/C130A/D144C
分子名称: Ferritin heavy chain, MAGNESIUM ION
著者Zang, J, Chen, H, Zhang, X, Zhao, G.
登録日2018-11-03
公開日2019-03-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.998 Å)
主引用文献Disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages.
Nat Commun, 10, 2019
3F8I
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Mouse UHRF1 SRA domain bound with hemi-methylated CpG, crystal structure in space group P21
分子名称: 5'-D(*DCP*DCP*DAP*DTP*DGP*(5CM)P*DGP*DCP*DTP*DGP*DAP*DC)-3', 5'-D(*DGP*DTP*DCP*DAP*DGP*DCP*DGP*DCP*DAP*DTP*DGP*DG)-3', E3 ubiquitin-protein ligase UHRF1
著者Hashimoto, H, Horton, J.R, Zhang, X, Cheng, X.
登録日2008-11-12
公開日2009-01-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications.
Epigenetics, 4, 2009
3FDE
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Mouse UHRF1 SRA domain bound with hemi-methylated CpG DNA, crystal structure in space group C222(1) at 1.4 A resolution
分子名称: 1,2-ETHANEDIOL, 5'-D(*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3', 5'-D(*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3', ...
著者Hashimoto, H, Horton, J.R, Zhang, X, Cheng, X.
登録日2008-11-25
公開日2009-01-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications.
Epigenetics, 4, 2009
3F8J
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Mouse UHRF1 SRA domain bound with hemi-methylated CpG, crystal structure in space group C222(1)
分子名称: 5'-D(*DCP*DCP*DAP*DTP*DGP*(5CM)P*DGP*DCP*DTP*DGP*DAP*DC)-3', 5'-D(*DGP*DTP*DCP*DAP*DGP*DCP*DGP*DCP*DAP*DTP*DGP*DG)-3', E3 ubiquitin-protein ligase UHRF1, ...
著者Hashimoto, H, Horton, J.R, Zhang, X, Cheng, X.
登録日2008-11-12
公開日2009-01-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications.
Epigenetics, 4, 2009
6GSB
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Sphingobacterium sp. T2 manganese superoxide dismutase catalyses the oxidative demethylation of polymeric lignin via generation of hydroxyl radical
分子名称: MANGANESE (II) ION, Superoxide dismutase
著者Rashid, G.M, Zhang, X, Wilkinson, R.C, Fulop, V, Cottyn, B, Baumberger, S, Bugg, D.H.
登録日2018-06-13
公開日2018-10-03
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Sphingobacterium sp. T2 Manganese Superoxide Dismutase Catalyzes the Oxidative Demethylation of Polymeric Lignin via Generation of Hydroxyl Radical.
ACS Chem. Biol., 13, 2018
6GSC
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Sphingobacterium sp. T2 manganese superoxide dismutase catalyses the oxidative demethylation of polymeric lignin via generation of hydroxyl radical
分子名称: MANGANESE (II) ION, Superoxide dismutase
著者Rashid, G.M.M, Zhang, X, Wilkinson, R.C, Fulop, V, Cottyn, B, Baumberger, S, Bugg, T.D.H.
登録日2018-06-13
公開日2018-10-03
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献Sphingobacterium sp. T2 Manganese Superoxide Dismutase Catalyzes the Oxidative Demethylation of Polymeric Lignin via Generation of Hydroxyl Radical.
ACS Chem. Biol., 13, 2018
4V40
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BETA-GALACTOSIDASE
分子名称: BETA-GALACTOSIDASE, MAGNESIUM ION
著者Jacobson, R.H, Zhang, X, Dubose, R.F, Matthews, B.W.
登録日1994-07-18
公開日2014-07-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Three-dimensional structure of beta-galactosidase from E. coli.
Nature, 369, 1994
5OAF
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Human Rvb1/Rvb2 heterohexamer in INO80 complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
著者Aramayo, R.J, Bythell-Douglas, R, Ayala, R, Willhoft, O, Wigley, D, Zhang, X.
登録日2017-06-21
公開日2017-12-13
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.06 Å)
主引用文献Cryo-EM structures of the human INO80 chromatin-remodeling complex.
Nat. Struct. Mol. Biol., 25, 2018
1WE1
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Crystal structure of heme oxygenase-1 from cyanobacterium Synechocystis sp. PCC6803 in complex with heme
分子名称: CHLORIDE ION, Heme oxygenase 1, ISOPROPYL ALCOHOL, ...
著者Sugishima, M, Migita, C.T, Zhang, X, Yoshida, T, Fukuyama, K.
登録日2004-05-21
公開日2004-12-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of heme oxygenase-1 from cyanobacterium Synechocystis sp. PCC 6803 in complex with heme
Eur.J.Biochem., 271, 2004
8EQB
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FAM46C/BCCIPalpha/Nanobody complex
分子名称: Isoform 2 of BRCA2 and CDKN1A-interacting protein, Synthetic nanobody 1, Terminal nucleotidyltransferase 5C
著者Liu, S, Chen, H, Yin, Y, Bai, X, Zhang, X.
登録日2022-10-07
公開日2023-03-15
最終更新日2023-04-26
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Inhibition of FAM46/TENT5 activity by BCCIP alpha adopting a unique fold.
Sci Adv, 9, 2023
5OQ4
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PQR309 - a Potent, Brain-Penetrant, Orally Bioavailable, pan-Class I PI3K/mTOR Inhibitor as Clinical Candidate in Oncology
分子名称: 5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION
著者Williams, R.L, Zhang, X.
登録日2017-08-10
公開日2017-09-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献5-(4,6-Dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine (PQR309), a Potent, Brain-Penetrant, Orally Bioavailable, Pan-Class I PI3K/mTOR Inhibitor as Clinical Candidate in Oncology.
J. Med. Chem., 60, 2017
5J6P
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Crystal Structure of Mis18(17-118) from Schizosaccharomyces pombe
分子名称: Kinetochore protein mis18, ZINC ION
著者Wang, C, Shao, C, Zhang, M, Zhang, X, Zang, J.
登録日2016-04-05
公開日2017-11-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of Mis18(17-118) from Schizosaccharomyces pombe
To Be Published
190D
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BU of 190d by Molmil
Crystal structure of a four-stranded intercalated DNA: d(C4)
分子名称: DNA (5'-D(*CP*CP*CP*C)-3')
著者Chen, L, Cai, L, Zhang, X, Rich, A.
登録日1994-09-02
公開日1995-02-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a four-stranded intercalated DNA: d(C4).
Biochemistry, 33, 1994
2NYD
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Crystal structure of Staphylococcus aureus hypothetical protein SA1388
分子名称: UPF0135 protein SA1388, ZINC ION
著者Singh, K.S, Zhang, X, Zhang, H.
登録日2006-11-20
公開日2007-01-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of a conserved hypothetical protein SA1388 from S. aureus reveals a capped hexameric toroid with two PII domain lids and a dinuclear metal center.
Bmc Struct.Biol., 6, 2006
1B5M
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RAT OUTER MITOCHONDRIAL MEMBRANE CYTOCHROME B5
分子名称: CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE
著者Rivera, M, White, S.P, Zhang, X.
登録日1996-11-07
公開日1997-03-12
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献13C NMR spectroscopic and X-ray crystallographic study of the role played by mitochondrial cytochrome b5 heme propionates in the electrostatic binding to cytochrome c.
Biochemistry, 35, 1996
1BR0
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THREE DIMENSIONAL STRUCTURE OF THE N-TERMINAL DOMAIN OF SYNTAXIN 1A
分子名称: PROTEIN (SYNTAXIN 1-A)
著者Fernandez, I, Ubach, J, Dubulova, I, Zhang, X, Sudhof, T.C, Rizo, J.
登録日1998-08-25
公開日1998-09-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Three-dimensional structure of an evolutionarily conserved N-terminal domain of syntaxin 1A.
Cell(Cambridge,Mass.), 94, 1998
1C76
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STAPHYLOKINASE (SAK) MONOMER
分子名称: STAPHYLOKINASE
著者Rao, Z, Jiang, F, Liu, Y, Zhang, X, Chen, Y, Bartlam, M, Song, H, Ding, Y.
登録日2000-02-01
公開日2000-08-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal Structure of Staphylokinase Dimer Offers New Clue to Reduction of Immunogenicity
To be published
8B4K
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Rfa1-N-terminal domain in complex with phosphorylated Ddc2
分子名称: Replication factor A protein 1
著者Yates, L.A, Zhang, X.
登録日2022-09-20
公開日2023-09-27
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献A DNA damage-induced phosphorylation circuit enhances Mec1 ATR Ddc2 ATRIP recruitment to Replication Protein A.
Proc.Natl.Acad.Sci.USA, 120, 2023
8B4J
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Rfa1-N-terminal domain in complex with phosphorylated Ddc2
分子名称: 1,2-ETHANEDIOL, DNA damage checkpoint protein LCD1, Replication factor A protein 1, ...
著者Yates, L.A, Zhang, X.
登録日2022-09-20
公開日2023-09-27
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献A DNA damage-induced phosphorylation circuit enhances Mec1 ATR Ddc2 ATRIP recruitment to Replication Protein A.
Proc.Natl.Acad.Sci.USA, 120, 2023
1BM6
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SOLUTION STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN STROMELYSIN-1 COMPLEXED TO A POTENT NON-PEPTIDIC INHIBITOR, NMR, 20 STRUCTURES
分子名称: 1-METHYLOXY-4-SULFONE-BENZENE, 3-METHYLPYRIDINE, CALCIUM ION, ...
著者Li, Y, Zhang, X, Melton, R, Ganu, V, Gonnella, N.C.
登録日1998-07-29
公開日1999-07-29
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the catalytic domain of human stromelysin-1 complexed to a potent, nonpeptidic inhibitor.
Biochemistry, 37, 1998
3KH8
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Crystal structure of MaoC-like dehydratase from Phytophthora Capsici
分子名称: MaoC-like dehydratase
著者Wang, H, Zhang, K, Guo, J, Zhou, Q, Zheng, X, Sun, F, Pang, H, Zhang, X.
登録日2009-10-30
公開日2010-11-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of MaoC-like dehydratase from Phytophthora Capsici
To be Published
4DEN
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Structural insightsinto potent, specific anti-HIV property of actinohivin; Crystal structure of actinohivin in complex with alpha(1-2) mannobiose moiety of high-mannose type glycan of gp120
分子名称: Actinohivin, POTASSIUM ION, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose
著者Hoque, M.M, Suzuki, K, Tsunoda, M, Jiang, J, Zhang, F, Takahashi, A, Naomi, O, Zhang, X, Sekiguchi, T, Tanaka, H, Omura, S, Takenaka, A.
登録日2012-01-20
公開日2012-11-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insights into the specific anti-HIV property of actinohivin: structure of its complex with the alpha(1–2)mannobiose moiety of gp120
Acta Crystallogr.,Sect.D, 68, 2012

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