6X1A
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![BU of 6x1a by Molmil](/molmil-images/mine/6x1a) | Non peptide agonist PF-06882961, bound to Glucagon-Like peptide-1 (GLP-1) Receptor | Descriptor: | 2-[(4-{6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-{[(2S)-oxetan-2-yl]methyl}-1H-benzimidazole-6-carboxylic acid, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Belousoff, M.J, Zhang, X, Danev, R. | Deposit date: | 2020-05-18 | Release date: | 2020-09-09 | Last modified: | 2020-11-18 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists. Mol.Cell, 80, 2020
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8KD3
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![BU of 8kd3 by Molmil](/molmil-images/mine/8kd3) | Rpd3S in complex with nucleosome with H3K36MLA modification, H3K9Q mutation and 187bp DNA | Descriptor: | 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ... | Authors: | Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J. | Deposit date: | 2023-08-09 | Release date: | 2023-09-13 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex. Cell Res., 33, 2023
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8KD6
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![BU of 8kd6 by Molmil](/molmil-images/mine/8kd6) | Rpd3S in complex with nucleosome with H3K36MLA modification and 187bp DNA, class3 | Descriptor: | 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ... | Authors: | Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J. | Deposit date: | 2023-08-09 | Release date: | 2023-09-13 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex. Cell Res., 33, 2023
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8KD4
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![BU of 8kd4 by Molmil](/molmil-images/mine/8kd4) | Rpd3S in complex with nucleosome with H3K36MLA modification and 187bp DNA, class1 | Descriptor: | 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ... | Authors: | Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J. | Deposit date: | 2023-08-09 | Release date: | 2023-09-13 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex. Cell Res., 33, 2023
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8KD2
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![BU of 8kd2 by Molmil](/molmil-images/mine/8kd2) | Rpd3S in complex with 187bp nucleosome | Descriptor: | 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ... | Authors: | Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J. | Deposit date: | 2023-08-09 | Release date: | 2023-09-13 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex. Cell Res., 33, 2023
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4EVV
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![BU of 4evv by Molmil](/molmil-images/mine/4evv) | mouse MBD4 glycosylase domain in complex with a G:T mismatch | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*CP*CP*AP*TP*GP*TP*GP*CP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3'), ... | Authors: | Hashimoto, H, Zhang, X, Cheng, X. | Deposit date: | 2012-04-26 | Release date: | 2012-07-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Excision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: structural basis and implications for active DNA demethylation. Nucleic Acids Res., 40, 2012
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6K5G
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![BU of 6k5g by Molmil](/molmil-images/mine/6k5g) | |
6K8P
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![BU of 6k8p by Molmil](/molmil-images/mine/6k8p) | |
4EW4
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![BU of 4ew4 by Molmil](/molmil-images/mine/4ew4) | mouse MBD4 glycosylase domain in complex with DNA containing a ribose sugar | Descriptor: | DNA (5'-D(*CP*CP*AP*TP*GP*(3DR)P*GP*CP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3'), Methyl-CpG-binding domain protein 4, ... | Authors: | Hashimoto, H, Zhang, X, Cheng, X. | Deposit date: | 2012-04-26 | Release date: | 2012-07-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.791 Å) | Cite: | Excision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: structural basis and implications for active DNA demethylation. Nucleic Acids Res., 40, 2012
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5E6P
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![BU of 5e6p by Molmil](/molmil-images/mine/5e6p) | |
4DHJ
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![BU of 4dhj by Molmil](/molmil-images/mine/4dhj) | The structure of a ceOTUB1 ubiquitin aldehyde UBC13~Ub complex | Descriptor: | Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ... | Authors: | Wiener, R, Zhang, X, Wang, T, Wolberger, C. | Deposit date: | 2012-01-27 | Release date: | 2012-02-22 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The mechanism of OTUB1-mediated inhibition of ubiquitination. Nature, 483, 2012
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2HMY
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![BU of 2hmy by Molmil](/molmil-images/mine/2hmy) | BINARY COMPLEX OF HHAI METHYLTRANSFERASE WITH ADOMET FORMED IN THE PRESENCE OF A SHORT NONPSECIFIC DNA OLIGONUCLEOTIDE | Descriptor: | PROTEIN (CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI), S-ADENOSYLMETHIONINE | Authors: | O'Gara, M, Zhang, X, Roberts, R.J, Cheng, X. | Deposit date: | 1999-02-08 | Release date: | 1999-03-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structure of a binary complex of HhaI methyltransferase with S-adenosyl-L-methionine formed in the presence of a short non-specific DNA oligonucleotide. J.Mol.Biol., 287, 1999
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6J7G
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![BU of 6j7g by Molmil](/molmil-images/mine/6j7g) | |
8IQ6
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![BU of 8iq6 by Molmil](/molmil-images/mine/8iq6) | Cryo-EM structure of Latanoprost-bound prostaglandin-F2-alpha receptor-miniGq-Nb35 complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Lv, X, Gao, K, Nie, J, Zhang, X, Zhang, S, Ren, Y, Li, Q, Huang, J, Liu, L, Zhang, X, Sun, X, Zhang, W, Liu, X. | Deposit date: | 2023-03-15 | Release date: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of human prostaglandin F 2 alpha receptor reveal the mechanism of ligand and G protein selectivity. Nat Commun, 14, 2023
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8IQ4
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![BU of 8iq4 by Molmil](/molmil-images/mine/8iq4) | Cryo-EM structure of Carboprost-bound prostaglandin-F2-alpha receptor-miniGq-Nb35 complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Lv, X, Gao, K, Nie, J, Zhang, X, Zhang, S, Ren, Y, Li, Q, Huang, J, Liu, L, Zhang, X, Sun, X, Zhang, W, Liu, X. | Deposit date: | 2023-03-15 | Release date: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structures of human prostaglandin F 2 alpha receptor reveal the mechanism of ligand and G protein selectivity. Nat Commun, 14, 2023
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5EWU
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![BU of 5ewu by Molmil](/molmil-images/mine/5ewu) | Crystal structure of the Arabidopsis thaliana C-terminal Chlh at 1.25A | Descriptor: | BENZOIC ACID, MAGNESIUM ION, Magnesium-chelatase subunit ChlH, ... | Authors: | Chen, Z, Zhang, X, Liu, Y, Jiang, L. | Deposit date: | 2015-11-21 | Release date: | 2016-12-07 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Crystal structure of the Arabidopsis thaliana C-terminal Chlh at 1.25A To Be Published
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2I89
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![BU of 2i89 by Molmil](/molmil-images/mine/2i89) | Structure of septuple mutant of Rat Outer Mitochondrial Membrane Cytochrome B5 | Descriptor: | Cytochrome b5 type B, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Terzyan, S, Zhang, X.C, Benson, D.R, Wang, L, Sun, N. | Deposit date: | 2006-09-01 | Release date: | 2006-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A histidine/tryptophan pi-stacking interaction stabilizes the heme-independent folding core of microsomal apocytochrome b5 relative to that of mitochondrial apocytochrome b5. Biochemistry, 45, 2006
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6VXK
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![BU of 6vxk by Molmil](/molmil-images/mine/6vxk) | Cryo-EM Structure of the full-length A39R/PlexinC1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-C1, Semaphorin-like protein 139 | Authors: | Kuo, Y.-C, Chen, H, Shang, G, Uchikawa, E, Tian, H, Bai, X, Zhang, X. | Deposit date: | 2020-02-22 | Release date: | 2020-04-29 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structure of the PlexinC1/A39R complex reveals inter-domain interactions critical for ligand-induced activation. Nat Commun, 11, 2020
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2IBJ
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![BU of 2ibj by Molmil](/molmil-images/mine/2ibj) | Structure of House Fly Cytochrome B5 | Descriptor: | Cytochrome b5, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Terzyan, S, Zhang, X.C, Benson, D.R, Wang, L. | Deposit date: | 2006-09-11 | Release date: | 2007-02-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Comparison of cytochromes b(5) from insects and vertebrates. Proteins, 67, 2007
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5V6T
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![BU of 5v6t by Molmil](/molmil-images/mine/5v6t) | The Plexin D1 intracellular region in complex with GIPC1 | Descriptor: | PDZ domain-containing protein GIPC1, Plexin-D1, SULFATE ION | Authors: | Shang, G, Zhang, X. | Deposit date: | 2017-03-17 | Release date: | 2017-05-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.189 Å) | Cite: | Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex. Elife, 6, 2017
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4F0P
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![BU of 4f0p by Molmil](/molmil-images/mine/4f0p) | MspJI Restriction Endonuclease - P31 Form | Descriptor: | MAGNESIUM ION, Restriction endonuclease | Authors: | Horton, J.R, Mabuchi, M, Cohen-Karni, D, Zhang, X, Griggs, R, Samaranayake, M, Roberts, R.J, Zheng, Y, Cheng, X. | Deposit date: | 2012-05-04 | Release date: | 2012-08-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structure and cleavage activity of the tetrameric MspJI DNA modification-dependent restriction endonuclease. Nucleic Acids Res., 40, 2012
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4F0Q
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![BU of 4f0q by Molmil](/molmil-images/mine/4f0q) | MspJI Restriction Endonuclease - P21 Form | Descriptor: | MAGNESIUM ION, Restriction endonuclease | Authors: | Horton, J.R, Mabuchi, M, Cohen-Karni, D, Zhang, X, Griggs, R, Samaranayake, M, Roberts, R.J, Zheng, Y, Cheng, X. | Deposit date: | 2012-05-04 | Release date: | 2012-08-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.046 Å) | Cite: | Structure and cleavage activity of the tetrameric MspJI DNA modification-dependent restriction endonuclease. Nucleic Acids Res., 40, 2012
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4F5X
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![BU of 4f5x by Molmil](/molmil-images/mine/4f5x) | Location of the dsRNA-dependent polymerase, VP1, in rotavirus particles | Descriptor: | Intermediate capsid protein VP6, RNA-directed RNA polymerase, VP2 protein, ... | Authors: | Estrozi, L.F, Settembre, E.C, Goret, G, McClain, B, Zhang, X, Chen, J.Z, Grigorieff, N, Harrison, S.C. | Deposit date: | 2012-05-13 | Release date: | 2012-10-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (5 Å) | Cite: | Location of the dsRNA-Dependent Polymerase, VP1, in Rotavirus Particles. J.Mol.Biol., 425, 2013
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1SQT
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![BU of 1sqt by Molmil](/molmil-images/mine/1sqt) | Substituted 2-Naphthamidine Inhibitors of Urokinase | Descriptor: | 7-METHOXY-8-[1-(METHYLSULFONYL)-1H-PYRAZOL-4-YL]NAPHTHALENE-2-CARBOXIMIDAMIDE, Urokinase-type plasminogen activator | Authors: | Wendt, M.D, Geyer, A, McClellan, W.J, Rockway, T.W, Weitzberg, M, Zhang, X, Mantei, R, Stewart, K, Nienaber, V, Klinghofer, V, Giranda, V.L. | Deposit date: | 2004-03-19 | Release date: | 2004-04-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Interaction with the S1beta-pocket of urokinase: 8-heterocycle substituted and 6,8-disubstituted 2-naphthamidine urokinase inhibitors. Bioorg.Med.Chem.Lett., 14, 2004
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5BQX
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![BU of 5bqx by Molmil](/molmil-images/mine/5bqx) | Crystal structure of human STING in complex with 3'2'-cGAMP | Descriptor: | 3'2'-cGAMP, Stimulator of interferon genes protein | Authors: | Wu, J, Zhang, X, Chen, Z.J, Chen, C. | Deposit date: | 2015-05-29 | Release date: | 2015-06-24 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis for the specific recognition of the metazoan cyclic GMP-AMP by the innate immune adaptor protein STING. Proc.Natl.Acad.Sci.USA, 112, 2015
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