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PDB: 1158 件

8FLM
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Cryo-EM structure of STING oligomer bound to cGAMP, NVS-STG2 and C53
分子名称: 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide, 4-({[4-(2-tert-butyl-5,5-dimethyl-1,3-dioxan-2-yl)phenyl]methyl}amino)-3-methoxybenzoic acid, Stimulator of interferon genes protein, ...
著者Li, J, Canham, S.M, Zhang, X, Bai, X, Feng, Y.
登録日2022-12-21
公開日2023-11-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Activation of human STING by a molecular glue-like compound.
Nat.Chem.Biol., 20, 2024
1R2Q
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Crystal Structure of Human Rab5a GTPase Domain at 1.05 A resolution
分子名称: GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Terzyan, S, Zhu, G, Li, G, Zhang, X.C.
登録日2003-09-29
公開日2003-12-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Refinement of the structure of human Rab5a GTPase domain at 1.05 A resolution.
Acta Crystallogr.,Sect.D, 60, 2004
4N2A
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Crystal structure of Protein Arginine Deiminase 2 (5 mM Ca2+)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Slade, D.J, Zhang, X, Fang, P, Dreyton, C.J, Zhang, Y, Gross, M.L, Guo, M, Coonrod, S.A, Thompson, P.R.
登録日2013-10-04
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.
Acs Chem.Biol., 10, 2015
4N25
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Crystal structure of Protein Arginine Deiminase 2 (250 uM Ca2+)
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ...
著者Slade, D.J, Zhang, X, Fang, P, Dreyton, C.J, Zhang, Y, Gross, M.L, Guo, M, Coonrod, S.A, Thompson, P.R.
登録日2013-10-04
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.931 Å)
主引用文献Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.
Acs Chem.Biol., 10, 2015
4N2N
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BU of 4n2n by Molmil
Crystal structure of Protein Arginine Deiminase 2 (E354A, 10 mM Ca2+)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Slade, D.J, Zhang, X, Fang, P, Dreyton, C.J, Zhang, Y, Gross, M.L, Guo, M, Coonrod, S.A, Thompson, P.R.
登録日2013-10-05
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.
Acs Chem.Biol., 10, 2015
4N2C
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Crystal structure of Protein Arginine Deiminase 2 (F221/222A, 10 mM Ca2+)
分子名称: CALCIUM ION, Protein-arginine deiminase type-2
著者Slade, D.J, Zhang, X, Fang, P, Dreyton, C.J, Zhang, Y, Gross, M.L, Guo, M, Coonrod, S.A, Thompson, P.R.
登録日2013-10-04
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.022 Å)
主引用文献Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.
Acs Chem.Biol., 10, 2015
4N2K
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Crystal structure of Protein Arginine Deiminase 2 (Q350A, 0 mM Ca2+)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, GLYCEROL, ...
著者Slade, D.J, Zhang, X, Fang, P, Dreyton, C.J, Zhang, Y, Gross, M.L, Guo, M, Coonrod, S.A, Thompson, P.R.
登録日2013-10-05
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.
Acs Chem.Biol., 10, 2015
3MHH
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BU of 3mhh by Molmil
Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module
分子名称: Protein SUS1, SAGA-associated factor 11, SAGA-associated factor 73, ...
著者Samara, N.L, Datta, A.B, Berndsen, C.E, Zhang, X, Yao, T, Cohen, R.E, Wolberger, C.
登録日2010-04-08
公開日2010-04-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural insights into the assembly and function of the SAGA deubiquitinating module.
Science, 328, 2010
5A9G
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Manganese Superoxide Dismutase from Sphingobacterium sp. T2
分子名称: MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE
著者Rashid, G.M.M, Taylor, C.R, Liu, Y, Zhang, X, Rea, D, Fulop, V, Bugg, T.D.H.
登録日2015-07-21
公開日2015-08-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Identification of Manganese Superoxide Dismutase from Sphingobacterium Sp. T2 as a Novel Bacterial Enzyme for Lignin Oxidation.
Acs Chem.Biol., 10, 2015
1PY1
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BU of 1py1 by Molmil
Complex of GGA1-VHS domain and beta-secretase C-terminal phosphopeptide
分子名称: ADP-ribosylation factor binding protein GGA1, Beta-secretase
著者Zhu, G, Zhang, X.C.
登録日2003-07-07
公開日2003-11-04
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Biochemical and structural characterization of the interaction of memapsin 2 (beta-secretase) cytosolic domain with the VHS domain of GGA proteins.
Biochemistry, 42, 2003
3MHS
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BU of 3mhs by Molmil
Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module bound to ubiquitin aldehyde
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Protein SUS1, ...
著者Samara, N.L, Datta, A.B, Berndsen, C.E, Zhang, X, Yao, T, Cohen, R.E, Wolberger, C.
登録日2010-04-08
公開日2010-04-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structural insights into the assembly and function of the SAGA deubiquitinating module.
Science, 328, 2010
4N2F
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BU of 4n2f by Molmil
Crystal structure of Protein Arginine Deiminase 2 (D169A, 0 mM Ca2+)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Slade, D.J, Zhang, X, Fang, P, Dreyton, C.J, Zhang, Y, Gross, M.L, Guo, M, Coonrod, S.A, Thompson, P.R.
登録日2013-10-04
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.
Acs Chem.Biol., 10, 2015
4N24
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Crystal structure of Protein Arginine Deiminase 2 (100 uM Ca2+)
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ...
著者Slade, D.J, Zhang, X, Fang, P, Dreyton, C.J, Zhang, Y, Gross, M.L, Guo, M, Coonrod, S.A, Thompson, P.R.
登録日2013-10-04
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.968 Å)
主引用文献Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.
Acs Chem.Biol., 10, 2015
4N2M
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BU of 4n2m by Molmil
Crystal structure of Protein Arginine Deiminase 2 (E354A, 0 mM Ca2+)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Slade, D.J, Zhang, X, Fang, P, Dreyton, C.J, Zhang, Y, Gross, M.L, Guo, M, Coonrod, S.A, Thompson, P.R.
登録日2013-10-05
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.
Acs Chem.Biol., 10, 2015
4N2G
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BU of 4n2g by Molmil
Crystal structure of Protein Arginine Deiminase 2 (D169A, 10 mM Ca2+)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Slade, D.J, Zhang, X, Fang, P, Dreyton, C.J, Zhang, Y, Gross, M.L, Guo, M, Coonrod, S.A, Thompson, P.R.
登録日2013-10-04
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.
Acs Chem.Biol., 10, 2015
4N28
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Crystal structure of Protein Arginine Deiminase 2 (1 mM Ca2+)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Slade, D.J, Zhang, X, Fang, P, Dreyton, C.J, Zhang, Y, Gross, M.L, Guo, M, Coonrod, S.A, Thompson, P.R.
登録日2013-10-04
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.879 Å)
主引用文献Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.
Acs Chem.Biol., 10, 2015
1L4Z
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BU of 1l4z by Molmil
X-RAY CRYSTAL STRUCTURE OF THE COMPLEX OF MICROPLASMINOGEN WITH ALPHA DOMAIN OF STREPTOKINASE IN THE PRESENCE CADMIUM IONS
分子名称: CADMIUM ION, Plasminogen, Streptokinase
著者Wakeham, N, Terzyan, S, Zhai, P, Loy, J.A, Tang, J, Zhang, X.C.
登録日2002-03-06
公開日2002-12-11
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Effects of deletion of streptokinase residues 48-59 on plasminogen activation.
PROTEIN ENG., 15, 2002
5X5B
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BU of 5x5b by Molmil
Prefusion structure of SARS-CoV spike glycoprotein, conformation 2
分子名称: Spike glycoprotein
著者Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F.
登録日2017-02-15
公開日2017-05-03
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
Nat Commun, 8, 2017
2Z41
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Crystal Structure Analysis of the Ski2-type RNA helicase
分子名称: MAGNESIUM ION, putative ski2-type helicase
著者Nakashima, T, Zhang, X, Kakuta, Y, Yao, M, Tanaka, I, Kimura, M.
登録日2007-06-12
公開日2008-04-08
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.51 Å)
主引用文献Crystal structure of an archaeal Ski2p-like protein from Pyrococcus horikoshii OT3
Protein Sci., 17, 2008
5X5C
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Prefusion structure of MERS-CoV spike glycoprotein, conformation 1
分子名称: S protein
著者Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F.
登録日2017-02-15
公開日2017-05-03
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
Nat Commun, 8, 2017
4DHJ
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BU of 4dhj by Molmil
The structure of a ceOTUB1 ubiquitin aldehyde UBC13~Ub complex
分子名称: Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ...
著者Wiener, R, Zhang, X, Wang, T, Wolberger, C.
登録日2012-01-27
公開日2012-02-22
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The mechanism of OTUB1-mediated inhibition of ubiquitination.
Nature, 483, 2012
5EWU
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BU of 5ewu by Molmil
Crystal structure of the Arabidopsis thaliana C-terminal Chlh at 1.25A
分子名称: BENZOIC ACID, MAGNESIUM ION, Magnesium-chelatase subunit ChlH, ...
著者Chen, Z, Zhang, X, Liu, Y, Jiang, L.
登録日2015-11-21
公開日2016-12-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Crystal structure of the Arabidopsis thaliana C-terminal Chlh at 1.25A
To Be Published
4AU6
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Location of the dsRNA-dependent polymerase, VP1, in rotavirus particles
分子名称: RNA-DEPENDENT RNA POLYMERASE
著者Estrozi, L.F, Settembre, E.C, Goret, G, McClain, B, Zhang, X, Chen, J.Z, Grigorieff, N, Harrison, S.C.
登録日2012-05-14
公開日2012-06-13
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Location of the Dsrna-Dependent Polymerase, Vp1, in Rotavirus Particles.
J.Mol.Biol., 425, 2013
1MVX
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structure of the SET domain histone lysine methyltransferase Clr4
分子名称: CRYPTIC LOCI REGULATOR 4, NICKEL (II) ION, SULFATE ION, ...
著者Min, J.R, Zhang, X, Cheng, X.D, Grewal, S.I.S, Xu, R.-M.
登録日2002-09-26
公開日2002-10-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the SET domain histone lysine methyltransferase Clr4.
Nat.Struct.Biol., 9, 2002
1MVH
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structure of the SET domain histone lysine methyltransferase Clr4
分子名称: Cryptic loci regulator 4, NICKEL (II) ION, SULFATE ION, ...
著者Min, J.R, Zhang, X, Cheng, X.D, Grewal, S.I.S, Xu, R.-M.
登録日2002-09-25
公開日2002-10-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the SET domain histone lysine methyltransferase Clr4.
Nat.Struct.Biol., 9, 2002

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